Epidermal growth factor receptor pathway substrate 15 (Q21105896)

http://www.ebi.ac.uk/interpro/protein/P42566

EF-hand domain, protein family

1 reference

EH domain, protein family

1 reference

Ubiquitin interacting motif, protein family

1 reference

EF-Hand 1, calcium-binding site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

SH3 domain binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

polyubiquitin modification-dependent protein binding

1 reference

8 April 2019

K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

protein binding

13 references

8 April 2019

Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 μ homology domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Characterization of the EFC/F-BAR domain protein, FCHO2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

The UBL domain of PLIC-1 regulates aggresome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

FCHo proteins are nucleators of clathrin-mediated endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Charting the molecular network of the drug target Bcr-Abl

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

cadherin binding

1 reference

17 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42566&geneProductId=UniProtKB:P42566

identical protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

cargo receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

cadherin binding

HDA

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

HDA

cell component

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

clathrin coat of coated pit

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

early endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

intracellular membrane-bounded organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

aggresome

1 reference

8 April 2019

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

ciliary membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

clathrin-coated pit

Cloning, expression, and localization of a novel gamma-adaptin-like molecule

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

AP-2 adaptor complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

clathrin-coated vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

basal plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

apical plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

early endosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

cytosol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

postsynapse

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

negative regulation of epidermal growth factor receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

epidermal growth factor receptor signaling pathway

1 reference

1 January 2018

The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

vesicle organization

1 reference

8 April 2019

Cloning, expression, and localization of a novel gamma-adaptin-like molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

Golgi to endosome transport

1 reference

8 April 2019

K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

clathrin coat assembly

1 reference

8 April 2019

Eps15 homology domain-NPF motif interactions regulate clathrin coat assembly during synaptic vesicle recycling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

viral entry into host cell

1 reference

8 April 2019

Ebola virus uses clathrin-mediated endocytosis as an entry pathway

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

receptor-mediated endocytosis of virus by host cell

1 reference

8 April 2019

The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

cell population proliferation

1 reference

1 January 2018

The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

positive regulation of receptor recycling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

membrane organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

viral process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

1 reference

8 April 2019

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42566&geneProductId=UniProtKB:P42566

1 reference

17 October 2017

postsynaptic neurotransmitter receptor internalization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42566

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016