(WWW - Medipdf.in) - 3rd Semester Blurprint B Pharm
(WWW - Medipdf.in) - 3rd Semester Blurprint B Pharm
(WWW - Medipdf.in) - 3rd Semester Blurprint B Pharm
KARNATAKA BENGALURU-560041
This subject deals with general methods of preparation and reactions of some organic
compounds. Reactivity of organic compounds are also studied here. The syllabus
emphasizes on mechanisms and orientation of reactions. Chemistry of fats and oils are
also included in the syllabus.
Course learning objectives: Upon completion of the course the student shall be able to
To provide the information about to write the structure, name, type of isomerism
of the organic compound
To provide basics of organic chemistry including writing the reaction,
mechanism, name the reaction and understand orientation of reactions
To provide adequate knowledge regarding principles of organic chemistry in the
field of reactivity,/stability of organic compounds,
Provide the information about the various techniques through demonstrations
involving synthesis of the organic compounds
Students are trained to purify and identify/confirm the organic compound
Learning Outcomes:
By applying examples they are able to define aromaticity, Orbital picture, resonance in
benzene, aromatic characters, Huckel‘s rule
Students are able to know different elecrtophillic reactions of benzene wise nitration,
sulphonation, halogenations, Friedel crafts alkylation- reactivity, limitations, Friedel
crafts acylation identify the nomenclature and type of organic reactions.
Students are able to know acidity of phenols, effect of substituents on acidity,
qualitative tests, Structure and uses of phenol, cresols, resorcinol, naphthols.
Students are able to know about Aromatic Amines, basicity of amines, effect of
substituents on basicity, and synthetic uses of aryl diazonium salts.
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Students are able to know about fats and oils wise their synthesis and reactions like
Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils. Students
are able to know Analytical constants of fats and oils like Acid value, Saponification
value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value –
significance and principle involved in their determination.
Students are able to know about synthesis and reactions of Polynuclear hydrocarbons
including their structure and medicinal uses.
Students are able to know the preparation of cycloalkanes and concepts of Bayer's strain
theory, theory of stainless ring and molecular orbital concept of cycloalkanes.
3. Annual objectives (for each year, if the subject is spread over different years): NA
2
4. Content distribution as per the list of topics, time allotted for each topic, distribution for ‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and
the probable weightage. The following table can also be a reference frame for continuous and formative assessment of learning. If the curriculum
management is scheduled as per the tabulation, there can be clarity for both learners and teachers to take stock of the mastery achieved in each
objective. This will also help for professional excellence that goes beyond the examination process.
3
2. Phenols* - Acidity of 10 Acidity of phenols, effect of Definition of acidity, --- 22
phenols, effect of substituent on acidity of phenols. acidity constant, chemistry of
substituent’s on acidity, qualitative tests, phenols.
qualitative tests, Structure Structure and uses of phenol,
and uses of phenol, cresols, cresols, resorcinol, naphthols
resorcinol, naphthols
Aromatic Amines* - Basicity of Amines, effect of
Basicity of amines, effect of substituent’s on basicity of aliphatic
substituents on basicity and and aromatic amines. Definition of basicity, basicity
synthetic uses of aryl Diazotisation and its mechanism, constant, chemistry of aromatic
diazonium salts. coupling reaction of Diazonium amines.
salts. Synthetic uses of aryl
diazonium salts.
Aromatic acids: acidity, acidity, effect of substituents on
effect of substituents on acidity and important reactions of
acidity and important benzoic acid
reactions of benzoic acid.
3. Fats and Oils 10 Definition, Properties and reactions . definition, chemistry, reactions, --- 21
of fats and oils with emphasis to
a. Fatty acids – reactions. classification, composition
Hydrolysis, hydrogenation,
b.Hydrolysis, hydrogenation, Saponification and Rancidity of
oils, Drying oils.
Saponification and Rancidity
Analytical constants – Acid value,
of oils, Drying oils. Saponification value, Ester value,
Iodine value, Acetyl value, Reichert
c. Analytical constants –
Meissl (RM) value – significance
Acid value, Saponification
and principle involved in their
value, Ester value, Iodine
determination
value, Acetyl value, Reichert
Meissl (RM) value –
significance and principle
involved in their
determination
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4. Polynuclear hydrocarbons: Definition, classification, Methods Definition, medicinal uses of ---
8 of synthesis Properties and polynuclear hydrocarbons and 16
a. Synthesis, reactions
Reaction of Poly nuclear derivatives.
b. Structure and medicinal
hydrocarbons Such as Naphthalene,
uses of Naphthalene,
Anthracene and Phenanthrene.
Phenanthrene, Anthracene,
Diphenylmethane,
Triphenylmethane and their
derivatives.
5. Cyclo alkanes* Preparation of cycloalkanes, Definition, anglestrain, reactions ---
Bayer's strain theory and its
Stabilities Baeyer‘s strain 7 limitations. Molecular orbital
theory, limitation of
concept. Coulson and Moffitt‘s
Baeyer‘s strain theory, 14
modification, Sache Mohr‘s theory
Coulson and Moffitt‘s
(Theory of strainless rings),
modification, Sache Mohr‘s
reactions of cyclopropane and
theory (Theory of
cyclobutane.
strainless rings), reactions of
cyclopropane and
cyclobutane only
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THIRD SEMESTER B PHARM- PHARMACEUTICAL ORGANIC CHEMISTRY-II
SHORT ANSWERS
SHORT ANSWE-
SHORT ESSAYS
SHORT ESSAYS
WEIGHTAGE OF
LONG ESSAYS
LONG ESSAYS
RS
MARKS
Unit No. TOPIC TITLE
HOURS
(10x3) (5x8) (2x4) (10x0) (5x1) (2x6)
NOTE: 1) the question paper must be prepared based on the individual blue print which is based on the weightage of
marks fixed for each chapter/unit
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Rajiv Gandhi University of Health Sciences, Karnataka
4th T Block Jayanagar, Bengaluru
Curriculum design, continuous and formative assessment evaluation of B. Pharm. course of
Semester IIIw.e.f Academic year 2018-19
SEMESTER-III
BP 302 T:Physical Pharmaceutics-I
5. Departmental objectives (what the learners will be able to perform after completing the subject):
A. Learning Objectives:
1. Understand various physicochemical properties of drug molecules in the designing the dosage
form
2. Know the principles of chemical kinetics & to use them in assigning expiry date for
Formulation
6. Content distribution as per the list of topics, time allotted for each topic, distribution for ‘Must
know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.
The following table can also be a reference frame for continuous and formative assessment of
learning. If the curriculum management is scheduled as per the tabulation, there can be clarity for
both learners and teachers to take stock of the mastery achieved in each objective. This will also
help for professional excellence that goes beyond the examination process.
7
Nice to know BCS Classification of drugs
8
Desirable to Buffers in pharmaceutical and biological systems, buffered isotonic
know solutions
Nice to know Importance of buffers in dissolution study
Blueprint of question paper for each QP. This shows the weightage given to each chapter in the
summative assessment. This improves the content validity by distributing the assessment of learners
in the competencies that are represented by learning objectives under each chapter.
LE SE SA LE SE SA of marks
(10X3) (5X8) (2X5) (10X0) (5X1) (2X5)
Unit-I 10 1 1 1 _ 1 - 22
Unit-II 10 1 1 1 _ 1 19
Unit-III 10 1 2 - _ 1 22
Unit-IV 08 - 2 2 _ 1 16
Unit-V 07 - 2 1 _ - 2 16
Total 45 30 40 10 - 5 10 95
80 15 95
__________________________
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Rajiv Gandhi University of Health Sciences, Karnataka
4th T Block Jayanagar, Bengaluru
Curriculum design, continuous and formative assessment evaluation of B.
Pharm. course of Semester 1 & 2 w.e.f Academic year 2018-19
SEMESTER-III
BP303T:Pharmaceutical Microbiology
8. Content distribution as per the list of topics, time allotted for each topic,
distribution for ‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the
probable weightage.
The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of
the mastery achieved in each objective. This will also help for professional
excellence that goes beyond the examination process.
10
-Special features of important culture media,
-Synchronous and diauxic growth.
-Classification of bacteria on physical factors affecting growth
-Industrially important preservation techniques.
Nice to know Scope of Pharmaceutically important branches of Microbiology
Accessory electronic gadgets.
-Example gram positive and negative pathogens.
-Medically important anaerobes.
-Endospores.
-Antibacterial agents used in their control.
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Nice to know -Pathogenic and opportunistic fungi and virus.
-Antiviral and antifungal agents used in their control.
-Standards for disinfectant fluids as per Schedule O of The drugs and
cosmetics act.
Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by
distributing the assessment of learners in the competencies that are represented by
learning objectives under each chapter.
12
BLUE PRINT OF MODEL QUESTION PAPER
BP303T: Pharmaceutical Microbiology
TIME: 3 HOURS MAX. MARKS: 75
__________________________
13
Rajiv Gandhi University of Health Sciences, Karnataka
4th T Block Jayanagar, Bengaluru
Curriculum delivery design of B. Pharm. course of Semester III System
w.e.f Academic year 2018-19
SEMESTER-III
BP 304 T. PHARMACEUTICAL ENGINEERING
14
10. Content distribution as per the list of topics, time allotted for each topic,
distribution for ‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the
probable weightage.
The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of
the mastery achieved in each objective. This will also help for professional
excellence that goes beyond the examination process.
15
Learning Evaporation
content
distribution
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UNIT-IV Hours: 8 Weightage: 14 Marks
Learning Topics
content
Filtration
distribution
Must know Principle, Construction, Working, Uses, Merits and demerits of
plate & frame filter, filter leaf, rotary drum filter, Meta filter &
Cartridge filter, membrane filters and Seidtz filter. Theories of
filtration
Desirable to Objectives, applications, Factors influencing filtration, filter aids,
know filter media.
Nice to know Latest filters available other than mentioned in the syllabus
Learning Centrifugation
content
distribution
17
Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by
distributing the assessment of learners in the competencies that are represented by
learning objectives under each chapter.
LE SE SA LE SE SA e of
(10X3) (5X8) (2X5) (10X0) (5X1) (2X5) marks
Unit-I 10 1 2 1 1 24
Unit-II 10 1 1 1 1 1 24
Unit-III 08 1 1 1 1 19
Unit-IV 08 2 1 1 14
Unit-V 09 2 1 1 14
Total 45 30 40 10 - 5 10 95
80 15 95
Question paper layout to show which question number will represent
which chapter (s)
Long Essay: 2X 10 = 20 Marks
1 Unit I (Must Know)
2 Unit II (Must Know)
3 Unit III (Must Know)
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