Skeletal muscle is composed of cylindrical muscle fibers surrounded by connective tissue. Each muscle fiber contains myofibrils which are made of repeating contractile units called sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments that overlap to allow contraction via a sliding filament mechanism. When an action potential reaches the neuromuscular junction, acetylcholine is released causing calcium release within the muscle fiber and allowing myosin to bind to and pull on actin, resulting in sarcomere shortening and muscle contraction.
Skeletal muscle is composed of cylindrical muscle fibers surrounded by connective tissue. Each muscle fiber contains myofibrils which are made of repeating contractile units called sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments that overlap to allow contraction via a sliding filament mechanism. When an action potential reaches the neuromuscular junction, acetylcholine is released causing calcium release within the muscle fiber and allowing myosin to bind to and pull on actin, resulting in sarcomere shortening and muscle contraction.
Skeletal muscle is composed of cylindrical muscle fibers surrounded by connective tissue. Each muscle fiber contains myofibrils which are made of repeating contractile units called sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments that overlap to allow contraction via a sliding filament mechanism. When an action potential reaches the neuromuscular junction, acetylcholine is released causing calcium release within the muscle fiber and allowing myosin to bind to and pull on actin, resulting in sarcomere shortening and muscle contraction.
Skeletal muscle is composed of cylindrical muscle fibers surrounded by connective tissue. Each muscle fiber contains myofibrils which are made of repeating contractile units called sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments that overlap to allow contraction via a sliding filament mechanism. When an action potential reaches the neuromuscular junction, acetylcholine is released causing calcium release within the muscle fiber and allowing myosin to bind to and pull on actin, resulting in sarcomere shortening and muscle contraction.
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CHAPTER 7: Muscular System Each fascicle is surrounded by a
connective tissue covering, termed the
PERIMYSIUM. Types of Muscles Each skeletal muscle cell (fiber) is surrounded by a Skeletal connective tissue covering, termed the attached to bones ENDOMYSIUM. Striated Muscle Fiber Structure voluntarily controlled Muscle Fiber Cardiac - is a single cylindrical cell, with several nuclei Located in he heart located at its periphery. Striated - range in length 1cm to 30cm and are involuntarily controlled generally 0.15 mm in diameter. Smooth Skeletal muscle fibers contain several nuclei that Located in the blood vessels, hollow are located at the periphery of the fiber. organs The sarcolemma (cell membrane) has many Non-striated tubelike inward folds, called transverse tubules, involuntarily controlled or T tubules Functions of Muscular System T tubules, 1. Movement - occur at regular intervals along the muscle 2. Maintain posture fiber and extend into the center of the muscle 3. Respiration fiber. 4. Production of body heat - T tubules are associated with enlarged 5. Communication portions of the smooth endoplasmic reticulum 6. Heart beat called the SARCOPLASMIC RETICULUM 7. Contraction of organs and vessels The enlarged portions are called TERMINAL Properties of Muscles CISTERNAE. Contractility - the ability of muscle to shorten The enlarged portions are called terminal forcefully, or contract cisternae. Excitability - the capacity of muscle to respond to The sarcoplasmic reticulum has a relatively high a stimulus concentration of Ca2 + , which plays a major role Extensibility - the ability to be stretched beyond it in muscle contraction. normal resting length and still be able to contract SARCOPLASM Elasticity - the ability of the muscle to recoil to its - Cytoplasm of a muscle fiber original resting length after it has been stretched - contains many bundles of protein Skeletal Muscle Structure filaments. Skeletal Muscle or striated muscle MYOFIBRILS With its associated connective tissue - bundles of protein filaments Constitutes approximately 40% of body weight. - Consist of: Skeletal muscle is so named because many of the o Myofilaments, Actin, Myosin muscles are attached to the skeletal system. The Sarcomere Skeletal muscle is also called striated muscle SARCOMERE because transverse bands, or striations can be - basic structural and functional unit of a seen in the muscle under the microscope. skeletal muscle because it is the smallest Individual skeletal muscles/Complete organs: portion of a skeletal muscle capable of Brachii and biceps. Result of being compromised contracting. of several tissues: muscle, nerve, and connective Z DISKS tissue. - form a network of protein fibers that both Connective Tissue Coverings serve as an anchor for actin myofilaments EPIMYSIUM- connective tissue sheath and separate one sarcomere from the surrounding each skeletal muscle. next. A sarcomere extends from one Z A skeletal muscle is subdivided into groups of disk to the next Z disk. A sarcomere muscle cells, termed FASCICLES. extends from one Z disk to the next Z disk. The Sarcomere POSTSYNAPTIC MEMBRANE The organization of actin and myosin - is the muscle fiber membrane myofilaments gives skeletal muscle its striated (sarcolemma). appearance and gives it the ability to contract SYNAPTIC VESICLE The myofilaments slide past each other, causing - e is a vesicle in the presynaptic terminal the sarcomeres to shorten. that stores and releases neurotransmitter Each sarcomere consists of two light-staining chemicals. bands separated by a dark-staining band. NEUROTRANSMITTERS Light Bands - are chemicals that stimulate or inhibit - consist only of actin, and are called I postsynaptic cells. bands that extends toward the center of ACETYLCHOLINE the sarcomere to the ends of the myosin - is the neurotransmitter that stimulates myofilaments. skeletal muscles Dark Staining Bands/A bands Muscle Contraction - that extend the length of the myosin 1. An action potential travels down motor neuron to myofilaments. presynaptic terminal causing Ca2+ channels to Actin and myosin myofilaments overlap for some open. distance on both ends of the A band; this overlap 2. 2. Ca2+ causes synaptic vesicles to release causes the contraction acetylcholine into synaptic cleft. ACTIN MYOFILAMENTS 3. Acetylcholine binds to receptor sites on Na+ - are made up of three components: actin, channels, Na+ channels open, and Na+ rushes troponin, and tropomyosin. into postsynaptic terminal (depolarization) TROPONIN 4. 4. Na+ causes sarcolemma and t-tubules to o molecules have binding sites for increase the permeability of sarcoplasmic Ca2 + and reticulum which releases stored calcium o TROPOMYOSIN FILAMENTS, block 5. Ca2+ binds to troponin which is attached to actin. the myosin myofilament binding 6. Ca2+ binding to troponin causes tropomyosin to sites on the actin myofilaments. move exposing attachment sites for myosin. MYOSIN MYOFILAMENTS 7. Myosin heads bind to actin. - thick myofilaments 8. ATP is released from myosin heads and heads - resemble bundles of tiny golf clubs. bend toward center of sarcomere. - resemble bundles of tiny golf clubs. 9. Bending forces actin to slide over myosin. Nerve Supply 10. Acetylcholinesterase (enzyme breaks down MOTOR NEURON acetylcholine) is released, Na+ channels close, - is a nerve cell stimulates muscle cells. and muscle contraction stops. NEUROMUSCULAR JUNSTION ATP and Muscle Contractions - is a synapse where a the fiber of a nerve Energy for muscle contractions is supplied by connects with a muscle fiber. ATP SYNAPSE Energy is released as ATP → ADP + P - refers to the cell-to-cell junction between ATP is stored in myosin heads a nerve cell and either another nerve cell ATP help form cross-bridge formation or an effector cell, such as in a muscle or a between myosin and actin gland. New ATP must bind to myosin before MOTOR UNIT crossbridge is released - is a group of muscle fibers that a motor Rigor mortis will occur when a person dies neuron stimulates. and no ATP is available to release cross- PRESYNAPTIC TERMINAL bridges - is the end of a neuron cell axon fiber. SYNAPTIC CLEFT - is the space between the presynaptic terminal and postsynaptic membrane. Types of Contraction SKELETAL MUSCLES Two types of muscle contractions: Anterior Isometric 1. Facial Muscles Isotonic 2. Sternocle ISOMETRIC 3. Trapezius - contraction has an increase in muscle 4. Deltoid tension, but no change in length. 5. Biceps brachii ISOTONIC 6. Linea alba - contraction has a change in muscle length 7. Brachioradialis with no change in tension 8. Retinaculum CONCENTRIC CONTRACTIONS 9. Pectoralis major - are isotonic contractions in which muscle 10. Serratus anterior tension increases as the muscle shortens. 11. Rectus Abdominis ECCENTRIC CONTRACTIONS 12. External abdominal oblique - are isotonic contractions in which tension 13. Flexors of wrist and fingers is maintained in a muscle, but the 14. Tensor fasciae latae opposing resistance causes the muscle to 15. Adductor Longus lengthen. 16. Gracilis Muscle Tone 17. Sartorius Muscle tone is the constant tension produced by 18. Patellar Tendon body muscles over long periods of time. 19. Patella Muscle tone is responsible for keeping the back 20. Gastrocnemius and legs straight, the head in an upright position, 21. Soleus and the abdomen from bulging. 22. Vastus Lateralis Smooth Muscle 23. Rectus Femoris Smooth muscle cells are non-striated small, 24. Vastus intermedius spindle-shaped muscle cells, usually with one (deep to the rectus femoris) nucleus per cell. 25. Vastus Medialis The myofilaments are not organized into 26. Tibialis Anterior sarcomeres. 27. Extensor Digitorum Longus The cells comprise organs controlled involuntarily, 28. Fibularis Longus except the heart. Neurotransmitter substances, hormones, and Posterior other substances can stimulate smooth muscle. 1. Sternocleidomastoid Cardiac Muscle 2. Trapezius Cardiac muscle cells are long, striated, and 3. Deltoid branching, with usually only one nucleus per cell. 4. Seventh cervical Vertebra Cardiac muscle is striated as a result of the 5. Infraspinatus sarcomere arrangement. 6. Teres Minor Cardiac muscle contraction is autorhythmic 7. Teres Major INTERCALATED DISKS 8. Triceps Brachii - Cardiac muscle cells are connected to one 9. Lastissmus Dorsi another by specialized structures that 10. External abdominal oblique include desmosomes and gap junctions 11. Gluteus Medius called intercalated disks. 12. Gluteus Maximus Cardiac muscle cells function as a single unit in 13. Adductor Magnus that action potential in one cardiac muscle cell 14. Illiotibial Tract can stimulate action potentials in adjacent cells. 15. Gracilis 16. Semitendinosus 17. Biceps Femoris 18. Semimembranous 19. Gastrocnemius 20. Soleus 21. Calcaneal Tendon Muscles of the Face (Achilles Tendon) FACIAL MUSCLES 22. Fibular Longus 1. Frontalis 23. Fibularis Brevis 2. Orbicularis Oculi 3. Orbicularis Oris Skeletal Muscle Anatomy 4. Buccinator 5. Zygomaticus TENDON 6. Masseter - connects skeletal muscle to bone. 7. Temporalis APONEUROSES 8. Levator Labii Superioris - are broad, sheetlike tendons. 9. Depressor Anguli Oris RETINACULUM Thoracic Muscles - is a band of connective tissue that holds External Intercostal down the tendons at each wrist and - elevate ribs for inspiration ankle. Internal Intercostal Skeletal muscle attachments have an origin and an - depress ribs during forced expiration insertion, with the origin being the attachment at Diaphragm the least mobile location - moves during quiet breathing The insertion is the end of the muscle attached to Abdominal Wall Muscles the bone undergoing the greatest movement. Rectus Abdominis The part of the muscle between the origin and the - center of abdomen insertion is the belly. - compresses abdomen AGONISTS External Abdominal Oblique - A group of muscles working together. - sides of abdomen ANTAGONISTS - compresses abdomen - muscle or group of muscles that oppose Internal Abdominal Oblique muscle actions - compresses abdomen Nomenclature Transverse Abdominis Muscles are named according to: - compresses abdomen 1. Location – a pectoralis muscle is located in Upper Scapular and Limbs Muscles the chest. Trapezius 2. Size – the size could be large or small, short or - shoulders and upper back long. - extends neck and head 3. Shape - the shape could be triangular, Pectoralis Major quadrate, rectangular, or round. - chest 4. Orientation of fascicles – fascicles could run - elevates ribs straight (rectus) or at an angle (oblique). Serratus Anterior 5. Origin and insertion. The sternocleidomastoid - between ribs has its origin on the sternum and clavicle and - elevates ribs its insertion on the mastoid process of the Deltoid temporal bone. - shoulder 6. Number of heads. A biceps muscle has two - abductor or upper limbs heads (origins), and a triceps muscle has three heads (origins). 7. Function. Abductors and adductors are the muscles that cause abduction and adduction movements. Upper Limb Muscles BICEPS FEMORIS, SEMIMEMBRANOSUS, Triceps Brachii SEMITENDINOSUS - 3 heads - Hamstring - extends elbow - back of thigh Biceps Brachii - flexes knee, rotates leg, extends hip - “flexing muscle” THE RECTUS FEMORIS: - flexes elbow and shoulder - front of thigh Brachialis - extends knee and flexes hip - flexes elbow THE RECTUS FEMORIS: Latissimus dorsi: - extends knee - lower back THE VASTUS MEDIALIS: - extends shoulder - extends knee Forearm Muscles THE VASTUS INTERMEDIUS: 1. Flexor longus - extends knee 2. Flexor carpi radialis Muscles of Lower Leg 3. Flexor carpi ulnari TIBIALIS ANTERIOR: 4. Flexor digitorum profundus - front of lower leg 5. Flexor digitorum superficialis - inverts foot 6. Pronator Brachioradialis GASTROCNEMIUS: 7. Extensor carpi radialis brevi - calf Pelvic Floor Muscles - flexes foot and leg 1. Levator ani SOLEUS: 2. Ischiocavernosus - attaches to ankle 3. Bulbospongiosus - flexes foot 4. Deep transverse perineal 5. Superficial transverse perinea Muscles of Hips and Thighs 1. Iliopsoas - flexes hip 2. Gluteus maximus - buttocks - extends hip and abducts thigh 3. Gluteus Medius - Hip - abducts and rotates thigh Muscles of the Upper Leg The quadriceps femoris is comprised of 4 thigh muscles: THE RECTUS FEMORIS: - front of thigh - extends knee and flexes hip THE VASTUS LATERALIS: - extends knee THE VASTUS MEDIALIS: - • extends knee THE VASTUS INTERMEDIUS: - extends knee GRACILIS - adducts thigh and flexes knee