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How Ivermectin Works

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Geoffrey Go
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164 views2 pages

How Ivermectin Works

Uploaded by

Geoffrey Go
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© © All Rights Reserved
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Studies have found 6 mechanisms by which Ivermectin prevents Covid 19

infections and cures it:

1.Ivermectin prevents the virus from entering target body cells even if it has already entered
through the mouth, nose, or eyes.

It binds into the spike - the corona - protein, making it unable to key into ACE-2 receptors at the
surface of the cells and making it open (https://pubmed.ncbi.nlm.nih.gov/32871846/). It’s like a
key smeared with epoxy that has hardened, it cannot fit into the keyhole anymore. This includes
emerging strains with mutations on the spike protein that threaten to disable existing vaccines.
Unlike the vaccines, this allows the immune system to develop antibodies – immunity - for each
emerging variant spike protein encountered
https://www.who.int/news-room/feature-stories/detail/how-do-vaccines-work

2.Even with the virus already inside the cells, Ivermectin prevents further entry to the cell
nucleus to control it and shut down the immune response. This is why initially, patients don’t feel
anything.

Ivermectin binds into Importin α/β1 heterodimer protein which the virus uses as the transport to
enter the cell's control center - its nucleus
https://pubmed.ncbi.nlm.nih.gov/22417684/

3.Ivermectin prevents the virus from replicating by inhibiting the Helicase enzyme it needs to do
so. This is why Ivermectin may also be effective against some forms of cancer.

Ivermectin inhibits the Helicase enzyme necessary to initiate genomic transcription and
eventually complete replication through protein translation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835698/

4.Ivermectin prevents COVID-19-induced Cytokine Storm that triggers respiratory distress


(ARDS) and attacks of immune cells on healthy organs resulting in organ damage, failure, and
mortality.

A cytokine storm is the release of a large amount of pro-inflammatory signaling molecules called
cytokines, causing multisystem organ failure and death. In SARS-COV-2, it also causes the
leakage of fluids into the alveolar spaces in the lungs, blocking Oxygen intake. Ivermectin is an
immuno-modulator that suppresses cytokine storms
https://pubmed.ncbi.nlm.nih.gov/19109745/

5.A fatal effect of SARS-COV-2 infection is the blood becoming sticky and blocking blood
vessels and Oxygen from being delivered to cells.
SARS-COV-2 infection uses the protein receptor CD147 in the membranes of red blood cells to
make the blood sticky and cause blockage in blood vessels. Ivermectin alleviates
CD147-mediated blood vessel blockage and blood clots
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3636557

6.Ivermectin increases Interferon production and enhances its effects.

Interferons are like bullets fired by the body's immune system that destroy viruses like
SARS-COV-2 upon entry. But when the viruses are so many that they overwhelm the body's
immune system, the undestroyed viruses stick to the target cells and get in to use them to
multiply and infect other cells. Increased Interferon production and enhancement in its effects
were observed in Onchocerciasis patients administered with Ivermectin
https://pubmed.ncbi.nlm.nih.gov/7930742/

In summary:

Ivermectin prevents infection.


It shortens the period of viral shedding making one stop transmitting the virus sooner.
It is an effective anti-viral and an anti inflammatory drug.

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