CH 5 Psychointetherap 2
CH 5 Psychointetherap 2
CH 5 Psychointetherap 2
PSYCHODYNAMIC-INTERPERSONAL THERAPY
Psychodynamic-Interpersonal Therapy:
An Overview of the Treatment Approach
and Evidence Base
Unconscious Processes
Theoretical Basis
Practice
the most costly to the health service and the prognosis for this group is
generally poor, without specific treatment.
There are four randomized controlled trials, which have evaluated
the effectiveness of PIT for patients with medically unexplained symp-
toms. Three have been conducted in Manchester and have focused
upon patients with unexplained bowel symptoms, and one has been
conducted in Germany with patients with mixed bodily complaints.
All the studies focused upon patients with severe and persistent symp-
toms, who had not responded to conventional treatments and who had
not been helped by specialist medical care.
The first study was published in 1991 and recruited 102 patients with
severe and intractable irritable bowel syndrome (Guthrie et al., 1991).
Patients were recruited consecutively from a gastrointestinal outpa-
tient clinic and randomized either to brief PIT or supportive therapy.
The PIT group received one long initial session of therapy lasting up to
3–4 hours followed by 6 sessions of 45 minutes, spread over 12 weeks.
Patients in the supportive limb were seen on 5 occasions for 30 min-
utes per session. The supportive sessions were used to control for the
nonspecific effects of therapy (e.g., seeing someone on a regular basis,
being listened to and supported). The outcome of the trial showed that
patients who received PIT showed a significant reduction in gut symp-
toms and psychological symptoms in comparison to the patients who
received support. The improvement in outcome was maintained over
12 months.
The second study recruited patients with severe and retractable func-
tional dyspepsia (i.e., patients with upper gastrointestinal complaints;
Hamilton et al., 2000). Patients in this study were randomized to PIT
versus supportive therapy. Patients who were randomized to the sup-
portive therapy received exactly the same amount of time with a thera-
pist and the therapy was again conducted over a 12-week period. The
outcome showed that PIT was superior to the supportive condition
both at the end of treatment and at follow-up six months later.
In the third trial, 257 patients with severe and persistent irritable
bowel syndrome were randomized to 12 weeks of PIT, or treatment
with an antidepressant or usual treatment (Creed et al., 2003). Detailed
assessments of outcomes and costs were undertaken. Both PIT and an-
tidepressant treatment resulted in significantly improved outcomes at
12 months posttreatment in relation to both physical and mental health.
PIT however was also associated with a significant reduction in health
care use in the 12 months posttreatment, compared with patients who
received usual care. So not only did PIT achieve a better outcome than
usual care, it also resulted in significant cost savings. The average sav-
ings per patient over a year were approximately £1000 at the time of
626 GUTHRIE AND MOGHAVEMI
publication and for patients with the most severe symptoms, cost sav-
ings were between £23000 per annum per patient.
The fourth study of PIT for patients with MUS was conducted in Ger-
many and recruited patients with persistent multisomatoform disorder
(Sattel et al., 2012). Multisomatoform disorder is characterized by se-
vere and disabling bodily symptoms of which pain is the most common
symptom. The trial was a multi-centre trial conducted in six different
centres in Germany. 211 patients were recruited to the study and were
randomized to either 12 weeks of PIT compared with 3 sessions of en-
hanced medical care; the best routine care that could be provided. Pa-
tients were followed up six months posttreatment. The main findings
were that patients who received the PIT showed significantly greater
improvement in physical and mental health function compared with
the control group over the course of the study.
Self-Harm
There has been one randomized controlled trial which has evaluated
PIT as a treatment for self-harm (Guthrie et al., 2001). In this study 119
patients who had presented to a U.K. emergency department after an
episode of self-poisoning were randomized to 4 sessions of home-based
PIT in comparison with usual treatment.
The therapists in the study were mental health nurses who were
trained to deliver PIT, but did not have any formal psychotherapy
qualification or prior training. The therapy was delivered at home to
increase engagement and compliance.
Participants who received the PIT had a significantly greater reduc-
tion in suicidal ideation at six-month follow-up compared with those in
the control group. They were much more satisfied with their treatment
and much less likely to report further self-harm during the six-month
follow-up period than participants who received usual care.
This study showed that nurses with good interpersonal skills can be
trained to deliver PIT for self-harm and deliver this treatment effec-
tively. Following this study, a PIT service for self-harm was established
in Manchester. Nurses in other hospitals such as Hull and the Wirral
have been trained in the model and have demonstrated good clinical
outcomes with reduction in service use (NHS Confederation Service).
A pilot project to deliver the therapy in prisons has been conducted and
a full evaluation is now underway.
PSYCHODYNAMIC-INTERPERSONAL THERAPY 627
Burns and colleagues (2005) assessed whether PIT could benefit cog-
nitive function and affective symptoms in patients with Alzheimer’s
disease. There was however no evidence of improvement on the main
outcome measures.
Service Evaluations
There have been several evaluations of PIT using before and after
designs in clinical service settings. Unlike trials, these studies provide
information about how PIT functions in “the real world.”
Guthrie and colleagues (2004) evaluated the effectiveness of PIT for
common mental health problems in primary care in a before and after
design. Primary care counsellors were trained in the model (see chapter
on training) and their treatment, using the model, was evaluated in 41
patients. The patients who they treated presented with a mix of mental
problems including mixed anxiety and depression, self-harm, alcohol
problems, and past histories of abuse. There was a significant reduction
in psychological symptoms over the course of the treatment and 50% of
the patients underwent clinically significant improvement.
Kellett and colleagues (Kellet, Clarke, & Matthews, 2007) compared
the outcome of 176 clients referred to a clinical psychology service who
were offered either group psychoeducational cognitive therapy (n = 43),
individual cognitive therapy (n = 68), or individual psychodynamic-
interpersonal therapy (n = 65). All three treatments showed equivalent
outcomes on most measures. The percentage of patients who showed
clinically significant change on the Beck Depression Inventory was 47%
for group CBT, 49% for individual CBT, and 62% for PIT.
Paley and colleagues (2008) evaluated the outcome of 67 patients
who received PIT in a routine NHS clinical setting. Outcomes were
assessed using a range of measures. Clinically significant change oc-
curred in 40% of clients, which is equivalent to the reported outcomes
of 41% achieved by cognitive behavioral therapies in the national psy-
chotherapy program rolled out recently in the U.K., called Improving
Access to Psychological Therapies (IAPT; Richards & Borglin, 2011).
Guthrie and Wells (1999) described providing brief PIT to three peo-
ple who developed posttraumatic stress disorder after being involved
in the Manchester Bombing. All three showed significant reductions in
PTSD symptoms.
630 GUTHRIE AND MOGHAVEMI
Process Research
There have been a variety of studies on PIT that have used psycho-
therapy process research methods to provide researchers with a way of
observing what therapists are doing in sessions and why. These studies
were carried out in Sheffield, principally involving data from the ran-
domized controlled trials comparing PIT with CBT for the treatment of
depression. Therapy sessions were audiotaped and patients and thera-
pists completed questionnaires after each session. The key researchers
involved in this work were David Shapiro, Michael Barkham, Gillian
Hardy, Robert Elliott, Bill Stiles, and Mike Startup.
Startup and Shapiro (1993a, 1993b; Shapiro & Startup, 1992) found
that when independent observers rated PIT and CBT sessions using
a system that defined behaviors of both therapies, the majority of ses-
sions were correctly assigned to the appropriate treatment. In further
observer-rated studies, therapists’ speech was coded using what are
called verbal response modes (VRMs). VRMs are categories of speech,
such as Disclosure, Question, Acknowledgement, and Reflection. PIT
therapists used more Simple Reflection, Interpretation, and Explorato-
ry Reflection, which are highly consistent with the PIT model (Hardy
& Shapiro, 1985; Stiles, 1989; Stiles & Shapiro, 1995; Stiles, Shapiro, &
Firth-Cozens, 1988).
This work established that therapists using PIT carry out interven-
tions during therapy consistent with the model. In other words, that
therapists generally behave in sessions according to the model of thera-
py they are delivering. Although this may sound a fairly obvious state-
ment, it is important to establish that therapists actually do what they
say they do.
Other studies have also supported the expected differences between
CBT and PIT therapists in their focus during sessions. For example, PIT
has a greater focus on within session experiences and the client’s past
and current relationships and emotional issues compared to CBT that
tends to focus on external situations and the future (Goldfried, Caston-
guay, Hayes, Drozd, & Shapiro, 1997).
PIT appears to require patients’ commitment to psychological ther-
apy prior to therapy starting. So, for example, both patients’ treatment
preferences and degree of psychological orientation predicted outcome
in PIT. These findings suggest therapists should socialize patients into
the treatment process. In other words, we should explain in detail to
clients how the therapy works, what to expect and what they can do to
maximize potential benefit.
PSYCHODYNAMIC-INTERPERSONAL THERAPY 631
Summary
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E. A. Guthrie, M.D.
Professor of Psychological Medicine and Medical Psychotherapy
Rawnsley Building
Manchester Royal Infirmary
Oxford Road
Manchester M 13 9WL U.K.
[email protected]