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Concept Map Hypercalcemia Final

This document discusses predisposing and precipitating factors for hypercalcemia. Predisposing factors include increasing age, female gender, and genetic factors. Precipitating factors can include hyperparathyroidism, cancers, and medications like thiazide diuretics which can cause loss of water and underexcretion of calcium leading to hypercalcemia. The diagram shows how these factors can cause hyperactive parathyroid glands to overproduce PTH and retain calcium in the blood.
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100% found this document useful (1 vote)
800 views1 page

Concept Map Hypercalcemia Final

This document discusses predisposing and precipitating factors for hypercalcemia. Predisposing factors include increasing age, female gender, and genetic factors. Precipitating factors can include hyperparathyroidism, cancers, and medications like thiazide diuretics which can cause loss of water and underexcretion of calcium leading to hypercalcemia. The diagram shows how these factors can cause hyperactive parathyroid glands to overproduce PTH and retain calcium in the blood.
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

PREDISPOSING FACTORS PRECIPITATING FACTORS

 Age  Hyperparathyroidism
 Gender  Cancers
 Genetics (Familial Hypocalciuric Hypercalcemia  Medications (Thiazide Diuretics)

Parathyroid gland
inactivating
hyperactive in
mutation of the Thiazide Diuretics Mutation
producing PTH
calcium-sensing inactivates tumor
receptor gene suppressor gene
Calcium blood Chemotherapy
Excess PTH
tests; >10.2 Loss of water and
released in Pamidronate
mg/dl underexcretion of Ca
bloodstream
inappropriate regulation of Gallium Nitrate Cell proliferation
Serum
passive paracellular calcium and inactivation of
creatinine
absorption in the loop of Henle Surgical Resection DNA-repair gene
Increase stimulation of test; elevated
bones to release >0.6 mg/dl Osmotic diuresis
Calcium
Failure of kidney to excrete Metastasis in the
calcium body
Calcium retained in MRI Scan; presence
blood of tumors
Excess Calcium in the Polyuria
kidneys
Dehydration Calcium release
from breakdown

Calcitonin

Surgical Neck Exploration/


Hypercalcemia
Removal

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