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Placenta
A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).
Placenta, Retained
A placenta that fails to be expelled after BIRTH of the FETUS. A PLACENTA is retained when the UTERUS fails to contract after the delivery of its content, or when the placenta is abnormally attached to the MYOMETRIUM.
Year introduced: 1995
Placenta Previa
Abnormal placentation in which the PLACENTA implants in the lower segment of the UTERUS (the zone of dilation) and may cover part or all of the opening of the CERVIX. It is often associated with serious antepartum bleeding and PREMATURE LABOR.
Year introduced: 2006 (1963)
Placenta Diseases
Pathological processes or abnormal functions of the PLACENTA.
Year introduced: 1980
Placenta Accreta
Abnormal placentation in which all or parts of the PLACENTA are attached directly to the MYOMETRIUM due to a complete or partial absence of DECIDUA. It is associated with POSTPARTUM HEMORRHAGE because of the failure of placental separation.
Placenta Growth Factor
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
Year introduced: 2017 (1991)
Postia placenta [Supplementary Concept]
Date introduced: October 1, 2020
Chorionic Villi
Threadlike vascular projections of the chorion. Chorionic villi may be free or embedded within the DECIDUA forming the site for exchange of substances between fetal and maternal blood (PLACENTA).
Year introduced: 1985(1975)
PLAC4 protein, human [Supplementary Concept]
RefSeq NM_182832
Date introduced: August 23, 2013
PLET1 protein, human [Supplementary Concept]
a specific marker of early thymic epithelial progenitor cells; RefSeq NM_001145024
Date introduced: February 8, 2008
PAPPA2 protein, human [Supplementary Concept]
RefSeq NM_021936
Date introduced: July 17, 2001
COLEC12 protein, human [Supplementary Concept]
RefSeq NM_130386
Date introduced: March 24, 2001
Psx1 protein, mouse [Supplementary Concept]
Psx is a homeobox gene expressed in mouse placenta; amino acid sequence in first source; GenBank AF017453; RefSeq NM_008955
Date introduced: August 10, 2000
INSL4 protein, human [Supplementary Concept]
RefSeq NM_002195
Date introduced: October 4, 1996
Melanoleuca grammopodia [Supplementary Concept]
PLAC1 protein, mouse [Supplementary Concept]
RefSeq NM_019538
Date introduced: April 21, 2014
Circumvallate Placenta Syndrome [Supplementary Concept]
Date introduced: November 5, 2012
COLEC12 protein, rat [Supplementary Concept]
RefSeq NM_001025721
Date introduced: September 15, 2011
Plet-1 protein, mouse [Supplementary Concept]
a specific marker of early thymic epithelial progenitor cells
PLAC8 protein, human [Supplementary Concept]
RefSeq NM_016619
Date introduced: December 8, 2005