Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a rare condition that is characterized by progressive damage (-pathy) to white matter (-leuko-) in the brain (-encephalo-), particularly myelin, due to causes such as exposure to drugs of abuse, environmental toxins, or chemotherapeutic drugs. The prevalence of this disease is infrequent and often goes unreported, especially in cases resulting from drug abuse. Magnetic resonance imaging (MRI) is a popular method to study and diagnose the disease. However, even with technological advances, the exact mechanism and underlying pathophysiology of toxic leukoencephalopathy remains unknown and is thought to vary between sources of toxicity. The clinical severity of toxic leukoencephalopathy also varies among patients, exposure time, and concentration and purity of the toxic agent. Some reversibility of the condition has been seen in many cases when the toxic agent is removed.
Causes
Various pharmacological agents have been known to cause toxic leukoencephalopathy. The most common causes are substance abuse drugs and chemotherapy; however, the disease has also occurred on the rare occasion as a side effect to certain medications and environmental toxins.
Case of the Week: Heroin-induced Leukoencephalopathy
Case of the week provides short summary of most interesting cases available in the RSNA Case Collection.
Visit the RSNA Case Collection to test your knowledge.
Link to RSNA case Collection: https://cases.rsna.org
Link to the case: https://doi.org/10.1148/cases.20227057
published: 13 Oct 2022
Methotrexate related Toxic Leucoencephalopathy with CLOCC
Speaker: Dr. Balaji Rao, MBBCh
Assistant Professor, Emergency Radiology and Neuroradiology,
Dept of Radiology and Biomedical Imaging,
Yale University School of Medicine
published: 04 Nov 2023
The Essentials of Acquired Brain Injury: Toxic and Chemical Encephalopathy: (3/6) .....
Exposure to toxins which are poisons produced by higher order plants, single celled organisms, and a variety of animals for defense and digestion and in the aid in hunting of prey, can cause significant acquired brain injury. Toxins can also be waste products produced by the body which it cannot remove due to illness or injury. Poisons can also be synthetic or semi-synthetic products made by humans in the laboratory or certain metals or metalloids extracted from the ground. Any toxin or chemical substance that damages neurons is a neurotoxin.
Toxin has become the term of art to describe poison regardless of its origin, whether its produced via an organic synthetic process or not. This video gives a survey of the most common types of neurotoxins, the general ways that they cause ...
published: 03 Jul 2023
TOXIC LEUKO-ENCEPHALOPATHY - A CASE BASED TUTORIAL ( C. T. SCAN)
#DrAnilJoshi #LearningRadiology #TOXICLEUKO-ENCEPHALOPATHY #C.T.SCAN #casebasedlearning. CASE BASED TUTORIAL ARE MENT FOR THE STUDENTS OF RADIO-DIAGNOSIS & IMAGING SCINCES . IMAGING FINDINGS OF PARTICULAR CASE BY MODALITIES LIKE CT, MRI, USG, RADIOGRAPHS WILL BE DISCUSED. THE INFORMATION GIVEN IS EXAMINATION ORIENTED & BRIEF. IT IS NEITHER COMPLETE NOR COMPRISENSIVE. FURTHER DETAILED ASPECTS SHOULD BE STUDIED FROM RELEVANT ACADEMIC SOURCES. IT SHOULD NOT BE USED FOR MEDICO-LEGAL PURPOSES.
LEARN RADIOLOGY WITH DR. ANIL JOSHI IS DEDICATED FOR TEACHING IMAGING PATTERNS OF DIFFERENT PATHOLOGIES. , MANY MORE ACADEMIC & RESEARCH WORK IS AVAILABLE IN MY YOU TUBE CHANNEL AS WELL AS IN MY WEBSITE.
#Radiologiest #learnonlineradiology #radiodiagnosis #radiologytutorial #radiologytechnologis...
published: 02 Sep 2022
Imaging of drug-related CNS-toxicity
Your brain on drugs! This presenation is part of a serie on imaging of toxic-metabolic brain disorders and deals with CNS-diseases caused by exposure to exogenous toxic substances, such as environmental toxis, medically prescribed and illegal drugs. Topics include carbon monoxide poisoning, acute toxic leukoencephalopathy, metronidozale, isoniazide and vigatrabin intoxication, and heroin- and MDMA-intoxication.
0:00 - Messing around
0:08 - Introduction
2:16 - Carbon Monoxide Poisoning
9:08 - Acute / Chronic Toxic Leukoencephalopathy
19:44 - Metronidazole Intoxication
24:28 - Vigatrabin Intoxication
27:37 - Recrational Drug Toxicity
29:31 - Heroin Intoxication (chasing the dragon)
35:18 - MDMA Intoxication
38:11 - Key Messages
This video is brought to you by the neuroradiologist:
https:/...
Aaron contracted Progressive PML due to on-going chemotherapy treatments. After JC virus-infected Aaron's brain he couldn't use the right side of his body or speak. After two weeks of treatment he is learning to walk and use his right arm again. Learn more at: http://cerebrum.com
Subscribe to our channel: http://bit.ly/1VOcJzR
MORE CEREBRUM CHANNELS:
Website: http://bit.ly/1KQF5o4
Facebook:https://www.facebook.com/CerebrumHealth
Twitter: https://twitter.com/CerebrumHealth
published: 08 Jan 2016
Progressive multifocal leukoencephalopathy
published: 12 Feb 2021
Leukoencephalopathy
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases.[1] It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
Progressive multifocal leukoencephalopathy
Toxic leukoencephalopathy
Leukoencephalopathy with vanishing white matter
Leukoencephalopathy with neuroaxonal spheroids
Reversible posterior leukoencephalopathy syndrome
Megalencephalic leukoencephalopathy with subcortical cysts. It can also refer to gene MLC1 or Megalencephalic leukoencephalopathy with subcortical cysts 1, a human gene related to the former disease.
Hypertensive leukoencephalopathy
The classification of leukoencephalopathies is a matter of debate. Some authors divide leukoencephalopathies into heredit...
published: 01 Sep 2017
White Matter Disease
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, Dr. Karen D. Sullivan discusses white matter disease: what it is, how it affects your brain health and what you can do about. Learn more at www.icfyb.com or follow us on Facebook at www.facebook.com/icareforyourbrain
published: 14 Dec 2022
Leukoencephalopathy
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases. It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
Case of the week provides short summary of most interesting cases available in the RSNA Case Collection.
Visit the RSNA Case Collection to test your knowledge...
Case of the week provides short summary of most interesting cases available in the RSNA Case Collection.
Visit the RSNA Case Collection to test your knowledge.
Link to RSNA case Collection: https://cases.rsna.org
Link to the case: https://doi.org/10.1148/cases.20227057
Case of the week provides short summary of most interesting cases available in the RSNA Case Collection.
Visit the RSNA Case Collection to test your knowledge.
Link to RSNA case Collection: https://cases.rsna.org
Link to the case: https://doi.org/10.1148/cases.20227057
Speaker: Dr. Balaji Rao, MBBCh
Assistant Professor, Emergency Radiology and Neuroradiology,
Dept of Radiology and Biomedical Imaging,
Yale University School of ...
Speaker: Dr. Balaji Rao, MBBCh
Assistant Professor, Emergency Radiology and Neuroradiology,
Dept of Radiology and Biomedical Imaging,
Yale University School of Medicine
Speaker: Dr. Balaji Rao, MBBCh
Assistant Professor, Emergency Radiology and Neuroradiology,
Dept of Radiology and Biomedical Imaging,
Yale University School of Medicine
Exposure to toxins which are poisons produced by higher order plants, single celled organisms, and a variety of animals for defense and digestion and in the ai...
Exposure to toxins which are poisons produced by higher order plants, single celled organisms, and a variety of animals for defense and digestion and in the aid in hunting of prey, can cause significant acquired brain injury. Toxins can also be waste products produced by the body which it cannot remove due to illness or injury. Poisons can also be synthetic or semi-synthetic products made by humans in the laboratory or certain metals or metalloids extracted from the ground. Any toxin or chemical substance that damages neurons is a neurotoxin.
Toxin has become the term of art to describe poison regardless of its origin, whether its produced via an organic synthetic process or not. This video gives a survey of the most common types of neurotoxins, the general ways that they cause injury and destruction to neurons, and discusses signs and symptoms of a usual neurotoxidrome associated with the typical case of Toxic Encephalopathy.
In this episode, we also discuss the "Other CTE: Chronic Toxic Encephalopathy..." and its associated signs and symptoms and how it is classified by OSHA and NIOSH.
There will be other episodes in which we describe specific cases of toxic encephalopathy and the signs and symptoms and what very few treatment options physicians and researchers have found. Unfortunately, funding is scarce in the field of toxicology.
Share with those who you feel will benefit.
Comment Below.
Please Like and Subscribe, Don't Forget the Bell, Click All.
#detoursunderstandingacquiredbraininjury #acquiredbraininjury #traumaticbraininjury #neurotrauma #neurotoxin #neurotoxic #braininjuryawareness #braindamage #braininjury #neurorehabilitation #neurodivergence #neurodiversity #ABI #TBI #headtrauma #disability #invisibledisability #invisibledisabilities
Exposure to toxins which are poisons produced by higher order plants, single celled organisms, and a variety of animals for defense and digestion and in the aid in hunting of prey, can cause significant acquired brain injury. Toxins can also be waste products produced by the body which it cannot remove due to illness or injury. Poisons can also be synthetic or semi-synthetic products made by humans in the laboratory or certain metals or metalloids extracted from the ground. Any toxin or chemical substance that damages neurons is a neurotoxin.
Toxin has become the term of art to describe poison regardless of its origin, whether its produced via an organic synthetic process or not. This video gives a survey of the most common types of neurotoxins, the general ways that they cause injury and destruction to neurons, and discusses signs and symptoms of a usual neurotoxidrome associated with the typical case of Toxic Encephalopathy.
In this episode, we also discuss the "Other CTE: Chronic Toxic Encephalopathy..." and its associated signs and symptoms and how it is classified by OSHA and NIOSH.
There will be other episodes in which we describe specific cases of toxic encephalopathy and the signs and symptoms and what very few treatment options physicians and researchers have found. Unfortunately, funding is scarce in the field of toxicology.
Share with those who you feel will benefit.
Comment Below.
Please Like and Subscribe, Don't Forget the Bell, Click All.
#detoursunderstandingacquiredbraininjury #acquiredbraininjury #traumaticbraininjury #neurotrauma #neurotoxin #neurotoxic #braininjuryawareness #braindamage #braininjury #neurorehabilitation #neurodivergence #neurodiversity #ABI #TBI #headtrauma #disability #invisibledisability #invisibledisabilities
#DrAnilJoshi #LearningRadiology #TOXICLEUKO-ENCEPHALOPATHY #C.T.SCAN #casebasedlearning. CASE BASED TUTORIAL ARE MENT FOR THE STUDENTS OF RADIO-DIAGNOSIS & IMA...
#DrAnilJoshi #LearningRadiology #TOXICLEUKO-ENCEPHALOPATHY #C.T.SCAN #casebasedlearning. CASE BASED TUTORIAL ARE MENT FOR THE STUDENTS OF RADIO-DIAGNOSIS & IMAGING SCINCES . IMAGING FINDINGS OF PARTICULAR CASE BY MODALITIES LIKE CT, MRI, USG, RADIOGRAPHS WILL BE DISCUSED. THE INFORMATION GIVEN IS EXAMINATION ORIENTED & BRIEF. IT IS NEITHER COMPLETE NOR COMPRISENSIVE. FURTHER DETAILED ASPECTS SHOULD BE STUDIED FROM RELEVANT ACADEMIC SOURCES. IT SHOULD NOT BE USED FOR MEDICO-LEGAL PURPOSES.
LEARN RADIOLOGY WITH DR. ANIL JOSHI IS DEDICATED FOR TEACHING IMAGING PATTERNS OF DIFFERENT PATHOLOGIES. , MANY MORE ACADEMIC & RESEARCH WORK IS AVAILABLE IN MY YOU TUBE CHANNEL AS WELL AS IN MY WEBSITE.
#Radiologiest #learnonlineradiology #radiodiagnosis #radiologytutorial #radiologytechnologist
#DrAnilJoshi #LearningRadiology #TOXICLEUKO-ENCEPHALOPATHY #C.T.SCAN #casebasedlearning. CASE BASED TUTORIAL ARE MENT FOR THE STUDENTS OF RADIO-DIAGNOSIS & IMAGING SCINCES . IMAGING FINDINGS OF PARTICULAR CASE BY MODALITIES LIKE CT, MRI, USG, RADIOGRAPHS WILL BE DISCUSED. THE INFORMATION GIVEN IS EXAMINATION ORIENTED & BRIEF. IT IS NEITHER COMPLETE NOR COMPRISENSIVE. FURTHER DETAILED ASPECTS SHOULD BE STUDIED FROM RELEVANT ACADEMIC SOURCES. IT SHOULD NOT BE USED FOR MEDICO-LEGAL PURPOSES.
LEARN RADIOLOGY WITH DR. ANIL JOSHI IS DEDICATED FOR TEACHING IMAGING PATTERNS OF DIFFERENT PATHOLOGIES. , MANY MORE ACADEMIC & RESEARCH WORK IS AVAILABLE IN MY YOU TUBE CHANNEL AS WELL AS IN MY WEBSITE.
#Radiologiest #learnonlineradiology #radiodiagnosis #radiologytutorial #radiologytechnologist
Your brain on drugs! This presenation is part of a serie on imaging of toxic-metabolic brain disorders and deals with CNS-diseases caused by exposure to exogeno...
Your brain on drugs! This presenation is part of a serie on imaging of toxic-metabolic brain disorders and deals with CNS-diseases caused by exposure to exogenous toxic substances, such as environmental toxis, medically prescribed and illegal drugs. Topics include carbon monoxide poisoning, acute toxic leukoencephalopathy, metronidozale, isoniazide and vigatrabin intoxication, and heroin- and MDMA-intoxication.
0:00 - Messing around
0:08 - Introduction
2:16 - Carbon Monoxide Poisoning
9:08 - Acute / Chronic Toxic Leukoencephalopathy
19:44 - Metronidazole Intoxication
24:28 - Vigatrabin Intoxication
27:37 - Recrational Drug Toxicity
29:31 - Heroin Intoxication (chasing the dragon)
35:18 - MDMA Intoxication
38:11 - Key Messages
This video is brought to you by the neuroradiologist:
https://twitter.com/theneuroradguy/
https://www.instagram.com/the_neurora...
https://theneuroradiologist.org/
#radiology #neuroradiology #neurology #radiology #neurosurgery #medicalstudent #medical #usmle #neuroradiologist #theneuroradiologist #brain #meded #foamed #anatomy #neuroanatomy #encephalopathy #drug
Your brain on drugs! This presenation is part of a serie on imaging of toxic-metabolic brain disorders and deals with CNS-diseases caused by exposure to exogenous toxic substances, such as environmental toxis, medically prescribed and illegal drugs. Topics include carbon monoxide poisoning, acute toxic leukoencephalopathy, metronidozale, isoniazide and vigatrabin intoxication, and heroin- and MDMA-intoxication.
0:00 - Messing around
0:08 - Introduction
2:16 - Carbon Monoxide Poisoning
9:08 - Acute / Chronic Toxic Leukoencephalopathy
19:44 - Metronidazole Intoxication
24:28 - Vigatrabin Intoxication
27:37 - Recrational Drug Toxicity
29:31 - Heroin Intoxication (chasing the dragon)
35:18 - MDMA Intoxication
38:11 - Key Messages
This video is brought to you by the neuroradiologist:
https://twitter.com/theneuroradguy/
https://www.instagram.com/the_neurora...
https://theneuroradiologist.org/
#radiology #neuroradiology #neurology #radiology #neurosurgery #medicalstudent #medical #usmle #neuroradiologist #theneuroradiologist #brain #meded #foamed #anatomy #neuroanatomy #encephalopathy #drug
Aaron contracted Progressive PML due to on-going chemotherapy treatments. After JC virus-infected Aaron's brain he couldn't use the right side of his body or sp...
Aaron contracted Progressive PML due to on-going chemotherapy treatments. After JC virus-infected Aaron's brain he couldn't use the right side of his body or speak. After two weeks of treatment he is learning to walk and use his right arm again. Learn more at: http://cerebrum.com
Subscribe to our channel: http://bit.ly/1VOcJzR
MORE CEREBRUM CHANNELS:
Website: http://bit.ly/1KQF5o4
Facebook:https://www.facebook.com/CerebrumHealth
Twitter: https://twitter.com/CerebrumHealth
Aaron contracted Progressive PML due to on-going chemotherapy treatments. After JC virus-infected Aaron's brain he couldn't use the right side of his body or speak. After two weeks of treatment he is learning to walk and use his right arm again. Learn more at: http://cerebrum.com
Subscribe to our channel: http://bit.ly/1VOcJzR
MORE CEREBRUM CHANNELS:
Website: http://bit.ly/1KQF5o4
Facebook:https://www.facebook.com/CerebrumHealth
Twitter: https://twitter.com/CerebrumHealth
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases.[1] It is applied to all brain white matter diseases, whether their molecular caus...
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases.[1] It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
Progressive multifocal leukoencephalopathy
Toxic leukoencephalopathy
Leukoencephalopathy with vanishing white matter
Leukoencephalopathy with neuroaxonal spheroids
Reversible posterior leukoencephalopathy syndrome
Megalencephalic leukoencephalopathy with subcortical cysts. It can also refer to gene MLC1 or Megalencephalic leukoencephalopathy with subcortical cysts 1, a human gene related to the former disease.
Hypertensive leukoencephalopathy
The classification of leukoencephalopathies is a matter of debate. Some authors divide leukoencephalopathies into hereditary disorders and acquired disorders. The hereditary demyelinating disorders are then classified according to the localization of the underlying metabolic defect, and they include the Leukodystrophies when myelin growth is the underlying problem.
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases.[1] It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
Progressive multifocal leukoencephalopathy
Toxic leukoencephalopathy
Leukoencephalopathy with vanishing white matter
Leukoencephalopathy with neuroaxonal spheroids
Reversible posterior leukoencephalopathy syndrome
Megalencephalic leukoencephalopathy with subcortical cysts. It can also refer to gene MLC1 or Megalencephalic leukoencephalopathy with subcortical cysts 1, a human gene related to the former disease.
Hypertensive leukoencephalopathy
The classification of leukoencephalopathies is a matter of debate. Some authors divide leukoencephalopathies into hereditary disorders and acquired disorders. The hereditary demyelinating disorders are then classified according to the localization of the underlying metabolic defect, and they include the Leukodystrophies when myelin growth is the underlying problem.
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, Dr. Karen D. Sullivan discusses white matter disease: what it is, how it affects your brain health ...
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, Dr. Karen D. Sullivan discusses white matter disease: what it is, how it affects your brain health and what you can do about. Learn more at www.icfyb.com or follow us on Facebook at www.facebook.com/icareforyourbrain
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, Dr. Karen D. Sullivan discusses white matter disease: what it is, how it affects your brain health and what you can do about. Learn more at www.icfyb.com or follow us on Facebook at www.facebook.com/icareforyourbrain
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases. It is applied to all brain white matter diseases, whether their molecular cause i...
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases. It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases. It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
Case of the week provides short summary of most interesting cases available in the RSNA Case Collection.
Visit the RSNA Case Collection to test your knowledge.
Link to RSNA case Collection: https://cases.rsna.org
Link to the case: https://doi.org/10.1148/cases.20227057
Speaker: Dr. Balaji Rao, MBBCh
Assistant Professor, Emergency Radiology and Neuroradiology,
Dept of Radiology and Biomedical Imaging,
Yale University School of Medicine
Exposure to toxins which are poisons produced by higher order plants, single celled organisms, and a variety of animals for defense and digestion and in the aid in hunting of prey, can cause significant acquired brain injury. Toxins can also be waste products produced by the body which it cannot remove due to illness or injury. Poisons can also be synthetic or semi-synthetic products made by humans in the laboratory or certain metals or metalloids extracted from the ground. Any toxin or chemical substance that damages neurons is a neurotoxin.
Toxin has become the term of art to describe poison regardless of its origin, whether its produced via an organic synthetic process or not. This video gives a survey of the most common types of neurotoxins, the general ways that they cause injury and destruction to neurons, and discusses signs and symptoms of a usual neurotoxidrome associated with the typical case of Toxic Encephalopathy.
In this episode, we also discuss the "Other CTE: Chronic Toxic Encephalopathy..." and its associated signs and symptoms and how it is classified by OSHA and NIOSH.
There will be other episodes in which we describe specific cases of toxic encephalopathy and the signs and symptoms and what very few treatment options physicians and researchers have found. Unfortunately, funding is scarce in the field of toxicology.
Share with those who you feel will benefit.
Comment Below.
Please Like and Subscribe, Don't Forget the Bell, Click All.
#detoursunderstandingacquiredbraininjury #acquiredbraininjury #traumaticbraininjury #neurotrauma #neurotoxin #neurotoxic #braininjuryawareness #braindamage #braininjury #neurorehabilitation #neurodivergence #neurodiversity #ABI #TBI #headtrauma #disability #invisibledisability #invisibledisabilities
#DrAnilJoshi #LearningRadiology #TOXICLEUKO-ENCEPHALOPATHY #C.T.SCAN #casebasedlearning. CASE BASED TUTORIAL ARE MENT FOR THE STUDENTS OF RADIO-DIAGNOSIS & IMAGING SCINCES . IMAGING FINDINGS OF PARTICULAR CASE BY MODALITIES LIKE CT, MRI, USG, RADIOGRAPHS WILL BE DISCUSED. THE INFORMATION GIVEN IS EXAMINATION ORIENTED & BRIEF. IT IS NEITHER COMPLETE NOR COMPRISENSIVE. FURTHER DETAILED ASPECTS SHOULD BE STUDIED FROM RELEVANT ACADEMIC SOURCES. IT SHOULD NOT BE USED FOR MEDICO-LEGAL PURPOSES.
LEARN RADIOLOGY WITH DR. ANIL JOSHI IS DEDICATED FOR TEACHING IMAGING PATTERNS OF DIFFERENT PATHOLOGIES. , MANY MORE ACADEMIC & RESEARCH WORK IS AVAILABLE IN MY YOU TUBE CHANNEL AS WELL AS IN MY WEBSITE.
#Radiologiest #learnonlineradiology #radiodiagnosis #radiologytutorial #radiologytechnologist
Your brain on drugs! This presenation is part of a serie on imaging of toxic-metabolic brain disorders and deals with CNS-diseases caused by exposure to exogenous toxic substances, such as environmental toxis, medically prescribed and illegal drugs. Topics include carbon monoxide poisoning, acute toxic leukoencephalopathy, metronidozale, isoniazide and vigatrabin intoxication, and heroin- and MDMA-intoxication.
0:00 - Messing around
0:08 - Introduction
2:16 - Carbon Monoxide Poisoning
9:08 - Acute / Chronic Toxic Leukoencephalopathy
19:44 - Metronidazole Intoxication
24:28 - Vigatrabin Intoxication
27:37 - Recrational Drug Toxicity
29:31 - Heroin Intoxication (chasing the dragon)
35:18 - MDMA Intoxication
38:11 - Key Messages
This video is brought to you by the neuroradiologist:
https://twitter.com/theneuroradguy/
https://www.instagram.com/the_neurora...
https://theneuroradiologist.org/
#radiology #neuroradiology #neurology #radiology #neurosurgery #medicalstudent #medical #usmle #neuroradiologist #theneuroradiologist #brain #meded #foamed #anatomy #neuroanatomy #encephalopathy #drug
Aaron contracted Progressive PML due to on-going chemotherapy treatments. After JC virus-infected Aaron's brain he couldn't use the right side of his body or speak. After two weeks of treatment he is learning to walk and use his right arm again. Learn more at: http://cerebrum.com
Subscribe to our channel: http://bit.ly/1VOcJzR
MORE CEREBRUM CHANNELS:
Website: http://bit.ly/1KQF5o4
Facebook:https://www.facebook.com/CerebrumHealth
Twitter: https://twitter.com/CerebrumHealth
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases.[1] It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
Progressive multifocal leukoencephalopathy
Toxic leukoencephalopathy
Leukoencephalopathy with vanishing white matter
Leukoencephalopathy with neuroaxonal spheroids
Reversible posterior leukoencephalopathy syndrome
Megalencephalic leukoencephalopathy with subcortical cysts. It can also refer to gene MLC1 or Megalencephalic leukoencephalopathy with subcortical cysts 1, a human gene related to the former disease.
Hypertensive leukoencephalopathy
The classification of leukoencephalopathies is a matter of debate. Some authors divide leukoencephalopathies into hereditary disorders and acquired disorders. The hereditary demyelinating disorders are then classified according to the localization of the underlying metabolic defect, and they include the Leukodystrophies when myelin growth is the underlying problem.
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, Dr. Karen D. Sullivan discusses white matter disease: what it is, how it affects your brain health and what you can do about. Learn more at www.icfyb.com or follow us on Facebook at www.facebook.com/icareforyourbrain
The term Leukoencephalopathy is a broad term for leukodystrophy-like diseases. It is applied to all brain white matter diseases, whether their molecular cause is known or not. It can refer specifically to any of these diseases:
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a rare condition that is characterized by progressive damage (-pathy) to white matter (-leuko-) in the brain (-encephalo-), particularly myelin, due to causes such as exposure to drugs of abuse, environmental toxins, or chemotherapeutic drugs. The prevalence of this disease is infrequent and often goes unreported, especially in cases resulting from drug abuse. Magnetic resonance imaging (MRI) is a popular method to study and diagnose the disease. However, even with technological advances, the exact mechanism and underlying pathophysiology of toxic leukoencephalopathy remains unknown and is thought to vary between sources of toxicity. The clinical severity of toxic leukoencephalopathy also varies among patients, exposure time, and concentration and purity of the toxic agent. Some reversibility of the condition has been seen in many cases when the toxic agent is removed.
Causes
Various pharmacological agents have been known to cause toxic leukoencephalopathy. The most common causes are substance abuse drugs and chemotherapy; however, the disease has also occurred on the rare occasion as a side effect to certain medications and environmental toxins.