Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons. When they occur within exons they either do not result in a change to the amino acid sequence of a protein (a "synonymous substitution"), or result in the insertion of an alternative amino acid with similar properties to that of the original amino acid; in either case there is no significant change in phenotype. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations only occur within exons, and are not always silent mutations. Synonymous mutations can affect transcription, splicing, mRNA transport, and translation, any of which could alter phenotype, rendering the synonymous mutation non-silent. The substrate specificity of the tRNA to the rare codon can affect the timing of translation, and in turn the co-translational folding of the protein. This is reflected in the codon usage bias that is observed in many species. Mutations that cause the altered codon to produce an amino acid with similar functionality (e.g. a mutation producing leucine instead of isoleucine) are often classified as silent; if the properties of the amino acid are conserved, this mutation does not usually significantly affect protein function.
This gene mutation lecture explains about silent mutation which is a type of point mutation. http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Jo...
published: 25 Mar 2015
The different types of mutations | Biomolecules | MCAT | Khan Academy
Created by Ross Firestone.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/the-causes-of-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/an-introduction-to-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners fr...
published: 03 Apr 2014
Genetics in 60 seconds: Nonsense, Missense, Silent Mutations
In this short video, I am going to explain the difference between nonsense, missense, and silent mutations.
NOTES: https://www.medicinecanbeeasy.com/
Disclaimer: This video is intended for educational purposes only and does not in any way constitute medical advice. If you suffer from a medical condition, you must seek a physician. This video does not in any way substitute medical diagnosis, treatment, and any other medical procedures provided by a qualified healthcare provider.
published: 16 Nov 2022
Mutations (Updated)
Join the Amoeba Sisters as they explain gene and chromosome mutations, and explore the significance of these changes. This updated video has improved audio and images! Check out our updated handout on https://www.amoebasisters.com/handouts and expand for table of contents!
Factual Reference:
OpenStax Biology 2nd Edition, Biology 2e. OpenStax CNX. May 8, 2019 http://cnx.org/contents/[email protected].
Codons and the amino acids they code for is represented by standard charts can be found in the public domain. While the rectangle chart is the common format, there may be other ways to represent the information. P.S. If exploring more about mutations, check out this cool codon chart that includes mutations(!!) in the public domain: https://commons.wikimedia.org/wiki...
published: 01 Aug 2019
Silent (synonymous) mutations of a gene explained
Degeneracy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify an amino acid. The degeneracy of the genetic code is what accounts for the existence of synonymous mutations.
Silent mutations are mutations in DNA that do not have an observable effect on the organism's phenotype. They are a specific type of neutral mutation. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations are not always silent, nor vice versa.
published: 20 Oct 2020
Genetics | A Comparison of Silent, Mis-sense, & Non-sense Mutations
⚡ Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT.
I hope you enjoy the video! Please leave a like and subscribe! 🙏
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published: 14 Apr 2019
Point Mutation- Nonsense mutation, Missense mutations, Silent mutations
This gene mutation lecture explains about silent mutation which is a type of point mutation. http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
htt...
This gene mutation lecture explains about silent mutation which is a type of point mutation. http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching
Silent mutations occur when there is a mis-incorporation of nucleotide in DNA which results in no change in the amino acid sequence during protein synthesis.
This gene mutation lecture explains about silent mutation which is a type of point mutation. http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching
Silent mutations occur when there is a mis-incorporation of nucleotide in DNA which results in no change in the amino acid sequence during protein synthesis.
Created by Ross Firestone.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/the-causes-of-genetic-mutations?u...
Created by Ross Firestone.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/the-causes-of-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/an-introduction-to-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Created by Ross Firestone.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/the-causes-of-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/an-introduction-to-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
In this short video, I am going to explain the difference between nonsense, missense, and silent mutations.
NOTES: https://www.medicinecanbeeasy.com/
Disclaim...
In this short video, I am going to explain the difference between nonsense, missense, and silent mutations.
NOTES: https://www.medicinecanbeeasy.com/
Disclaimer: This video is intended for educational purposes only and does not in any way constitute medical advice. If you suffer from a medical condition, you must seek a physician. This video does not in any way substitute medical diagnosis, treatment, and any other medical procedures provided by a qualified healthcare provider.
In this short video, I am going to explain the difference between nonsense, missense, and silent mutations.
NOTES: https://www.medicinecanbeeasy.com/
Disclaimer: This video is intended for educational purposes only and does not in any way constitute medical advice. If you suffer from a medical condition, you must seek a physician. This video does not in any way substitute medical diagnosis, treatment, and any other medical procedures provided by a qualified healthcare provider.
Join the Amoeba Sisters as they explain gene and chromosome mutations, and explore the significance of these changes. This updated video has improved audio and ...
Join the Amoeba Sisters as they explain gene and chromosome mutations, and explore the significance of these changes. This updated video has improved audio and images! Check out our updated handout on https://www.amoebasisters.com/handouts and expand for table of contents!
Factual Reference:
OpenStax Biology 2nd Edition, Biology 2e. OpenStax CNX. May 8, 2019 http://cnx.org/contents/[email protected].
Codons and the amino acids they code for is represented by standard charts can be found in the public domain. While the rectangle chart is the common format, there may be other ways to represent the information. P.S. If exploring more about mutations, check out this cool codon chart that includes mutations(!!) in the public domain: https://commons.wikimedia.org/wiki/File:Notable_mutations.svg
***Further Reading Suggestions to Go Beyond This Content!***
-Yes, mutations can happen in viruses! Check out master teacher John Mead's National Geographic Education blog post on this with the influenza virus:
https://blog.education.nationalgeographic.org/2017/12/08/talking-evolution-the-challenge-of-influenza-part-2/
-Mutations in fruit flies? Learn more:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649653/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349060/
-Careers in Genetics?
National Society of Genetic Counselors: https://www.nsgc.org/page/aboutgeneticcounselors
Bioinformatics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408859/
Flowchart from American Society of Human Genetics- http://www.ashg.org/education/career_flowchart.shtml
The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching biology at the high school level. Learn more about our videos here: https://www.amoebasisters.com/our-videos
⭐We have a menu of our resources that complement our videos! Visit https://docs.google.com/spreadsheets/d/1b3kmAzFEjWgoMKCrkeNCKFYunWk04IuLY93jI4OY0gY/edit?usp=sharing
Support Us? https://www.amoebasisters.com/support-us
Our Resources:
Biology Playlist: https://www.youtube.com/playlist?list=PLwL0Myd7Dk1F0iQPGrjehze3eDpco1eVz
GIFs: https://www.amoebasisters.com/gifs.html
Handouts: https://www.amoebasisters.com/handouts.html
Comics: https://www.amoebasisters.com/parameciumparlorcomics
Unlectured Series: https://www.amoebasisters.com/unlectured
Connect with us!
Website: http://www.AmoebaSisters.com
Twitter: http://www.twitter.com/AmoebaSisters
Facebook: http://www.facebook.com/AmoebaSisters
Tumblr: http://www.amoebasisters.tumblr.com
Pinterest: http://www.pinterest.com/AmoebaSisters
Instagram: https://www.instagram.com/amoebasistersofficial/
Visit our Redbubble store at https://www.amoebasisters.com/store
TIPS FOR VIEWING EDU YOUTUBE VIDEOS:
Want to learn tips for viewing edu YouTube videos including changing the speed, language, viewing the transcript, etc? https://www.amoebasisters.com/pinkys-ed-tech-favorites/10-youtube-tips-from-an-edu-youtuber-duo
MUSIC:
Our intro music designed and performed by Jeremiah Cheshire.
End music in this video is listed free to use/no attribution required from the YouTube audio library https://www.youtube.com/audiolibrary/music?feature=blog
COMMUNITY:
We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See YouTube's community guidelines and how YouTube handles comments that are reported by the community. We also reserve the right to remove comments.
TRANSLATIONS:
Hindi Subtitles Credit: Alisha Aggarwal
Turkish Subtitles Credit: Emre Durak
Some translated subtitles on our videos were translated by the community using YouTube's community-contributed subtitle feature. After the feature was discontinued by YouTube, we have another option for submitting translated subtitles here: https://www.amoebasisters.com/pinkys-ed-tech-favorites/community-contributed-subtitles We want to thank our amazing community for the generosity of their time in continuing to create translated subtitles. If you have a concern about community contributed contributions, please contact us.
Our Amoeba Sisters en Español channel has our videos dubbed in Spanish! https://www.youtube.com/channel/UC1Njo3LBy53cOPngz6ArV8Q
Join the Amoeba Sisters as they explain gene and chromosome mutations, and explore the significance of these changes. This updated video has improved audio and images! Check out our updated handout on https://www.amoebasisters.com/handouts and expand for table of contents!
Factual Reference:
OpenStax Biology 2nd Edition, Biology 2e. OpenStax CNX. May 8, 2019 http://cnx.org/contents/[email protected].
Codons and the amino acids they code for is represented by standard charts can be found in the public domain. While the rectangle chart is the common format, there may be other ways to represent the information. P.S. If exploring more about mutations, check out this cool codon chart that includes mutations(!!) in the public domain: https://commons.wikimedia.org/wiki/File:Notable_mutations.svg
***Further Reading Suggestions to Go Beyond This Content!***
-Yes, mutations can happen in viruses! Check out master teacher John Mead's National Geographic Education blog post on this with the influenza virus:
https://blog.education.nationalgeographic.org/2017/12/08/talking-evolution-the-challenge-of-influenza-part-2/
-Mutations in fruit flies? Learn more:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649653/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349060/
-Careers in Genetics?
National Society of Genetic Counselors: https://www.nsgc.org/page/aboutgeneticcounselors
Bioinformatics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408859/
Flowchart from American Society of Human Genetics- http://www.ashg.org/education/career_flowchart.shtml
The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching biology at the high school level. Learn more about our videos here: https://www.amoebasisters.com/our-videos
⭐We have a menu of our resources that complement our videos! Visit https://docs.google.com/spreadsheets/d/1b3kmAzFEjWgoMKCrkeNCKFYunWk04IuLY93jI4OY0gY/edit?usp=sharing
Support Us? https://www.amoebasisters.com/support-us
Our Resources:
Biology Playlist: https://www.youtube.com/playlist?list=PLwL0Myd7Dk1F0iQPGrjehze3eDpco1eVz
GIFs: https://www.amoebasisters.com/gifs.html
Handouts: https://www.amoebasisters.com/handouts.html
Comics: https://www.amoebasisters.com/parameciumparlorcomics
Unlectured Series: https://www.amoebasisters.com/unlectured
Connect with us!
Website: http://www.AmoebaSisters.com
Twitter: http://www.twitter.com/AmoebaSisters
Facebook: http://www.facebook.com/AmoebaSisters
Tumblr: http://www.amoebasisters.tumblr.com
Pinterest: http://www.pinterest.com/AmoebaSisters
Instagram: https://www.instagram.com/amoebasistersofficial/
Visit our Redbubble store at https://www.amoebasisters.com/store
TIPS FOR VIEWING EDU YOUTUBE VIDEOS:
Want to learn tips for viewing edu YouTube videos including changing the speed, language, viewing the transcript, etc? https://www.amoebasisters.com/pinkys-ed-tech-favorites/10-youtube-tips-from-an-edu-youtuber-duo
MUSIC:
Our intro music designed and performed by Jeremiah Cheshire.
End music in this video is listed free to use/no attribution required from the YouTube audio library https://www.youtube.com/audiolibrary/music?feature=blog
COMMUNITY:
We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See YouTube's community guidelines and how YouTube handles comments that are reported by the community. We also reserve the right to remove comments.
TRANSLATIONS:
Hindi Subtitles Credit: Alisha Aggarwal
Turkish Subtitles Credit: Emre Durak
Some translated subtitles on our videos were translated by the community using YouTube's community-contributed subtitle feature. After the feature was discontinued by YouTube, we have another option for submitting translated subtitles here: https://www.amoebasisters.com/pinkys-ed-tech-favorites/community-contributed-subtitles We want to thank our amazing community for the generosity of their time in continuing to create translated subtitles. If you have a concern about community contributed contributions, please contact us.
Our Amoeba Sisters en Español channel has our videos dubbed in Spanish! https://www.youtube.com/channel/UC1Njo3LBy53cOPngz6ArV8Q
Degeneracy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify an amino acid. The ...
Degeneracy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify an amino acid. The degeneracy of the genetic code is what accounts for the existence of synonymous mutations.
Silent mutations are mutations in DNA that do not have an observable effect on the organism's phenotype. They are a specific type of neutral mutation. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations are not always silent, nor vice versa.
Degeneracy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify an amino acid. The degeneracy of the genetic code is what accounts for the existence of synonymous mutations.
Silent mutations are mutations in DNA that do not have an observable effect on the organism's phenotype. They are a specific type of neutral mutation. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations are not always silent, nor vice versa.
⚡ Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT.
I hope you enjoy the video! Please leave a like and subscribe! 🙏
INSTAGRAM | @thecatalystunivers...
⚡ Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT.
I hope you enjoy the video! Please leave a like and subscribe! 🙏
INSTAGRAM | @thecatalystuniversity
Follow me on Instagram @thecatalystuniversity for additional helpful content and for my more fun side: Pets, Workouts, Dragon Ball Z
SleepPhones® | Need to Relax? Ocean waves, ASMR, Rainstorms, and Theta Waves while you sleep with SleepPhones® at this link: https://www.sleepphones.com/?aff=394 - Use the Coupon Code, “CatalystRelax”, at the checkout for some awesome savings.
More details here in my new video: https://youtu.be/qcVFzpO-xC8
MERCHANDISE
Be sure to check out custom Catalyst University merchandise!
LINK | https://teespring.com/stores/catalyst-university-store-2
PATREON
LINK | https://www.patreon.com/catalystuniversity
⚡ Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT.
I hope you enjoy the video! Please leave a like and subscribe! 🙏
INSTAGRAM | @thecatalystuniversity
Follow me on Instagram @thecatalystuniversity for additional helpful content and for my more fun side: Pets, Workouts, Dragon Ball Z
SleepPhones® | Need to Relax? Ocean waves, ASMR, Rainstorms, and Theta Waves while you sleep with SleepPhones® at this link: https://www.sleepphones.com/?aff=394 - Use the Coupon Code, “CatalystRelax”, at the checkout for some awesome savings.
More details here in my new video: https://youtu.be/qcVFzpO-xC8
MERCHANDISE
Be sure to check out custom Catalyst University merchandise!
LINK | https://teespring.com/stores/catalyst-university-store-2
PATREON
LINK | https://www.patreon.com/catalystuniversity
This gene mutation lecture explains about silent mutation which is a type of point mutation. http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching
Silent mutations occur when there is a mis-incorporation of nucleotide in DNA which results in no change in the amino acid sequence during protein synthesis.
Created by Ross Firestone.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/the-causes-of-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/an-introduction-to-genetic-mutations?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
In this short video, I am going to explain the difference between nonsense, missense, and silent mutations.
NOTES: https://www.medicinecanbeeasy.com/
Disclaimer: This video is intended for educational purposes only and does not in any way constitute medical advice. If you suffer from a medical condition, you must seek a physician. This video does not in any way substitute medical diagnosis, treatment, and any other medical procedures provided by a qualified healthcare provider.
Join the Amoeba Sisters as they explain gene and chromosome mutations, and explore the significance of these changes. This updated video has improved audio and images! Check out our updated handout on https://www.amoebasisters.com/handouts and expand for table of contents!
Factual Reference:
OpenStax Biology 2nd Edition, Biology 2e. OpenStax CNX. May 8, 2019 http://cnx.org/contents/[email protected].
Codons and the amino acids they code for is represented by standard charts can be found in the public domain. While the rectangle chart is the common format, there may be other ways to represent the information. P.S. If exploring more about mutations, check out this cool codon chart that includes mutations(!!) in the public domain: https://commons.wikimedia.org/wiki/File:Notable_mutations.svg
***Further Reading Suggestions to Go Beyond This Content!***
-Yes, mutations can happen in viruses! Check out master teacher John Mead's National Geographic Education blog post on this with the influenza virus:
https://blog.education.nationalgeographic.org/2017/12/08/talking-evolution-the-challenge-of-influenza-part-2/
-Mutations in fruit flies? Learn more:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649653/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349060/
-Careers in Genetics?
National Society of Genetic Counselors: https://www.nsgc.org/page/aboutgeneticcounselors
Bioinformatics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408859/
Flowchart from American Society of Human Genetics- http://www.ashg.org/education/career_flowchart.shtml
The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching biology at the high school level. Learn more about our videos here: https://www.amoebasisters.com/our-videos
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Degeneracy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify an amino acid. The degeneracy of the genetic code is what accounts for the existence of synonymous mutations.
Silent mutations are mutations in DNA that do not have an observable effect on the organism's phenotype. They are a specific type of neutral mutation. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations are not always silent, nor vice versa.
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Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons. When they occur within exons they either do not result in a change to the amino acid sequence of a protein (a "synonymous substitution"), or result in the insertion of an alternative amino acid with similar properties to that of the original amino acid; in either case there is no significant change in phenotype. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations only occur within exons, and are not always silent mutations. Synonymous mutations can affect transcription, splicing, mRNA transport, and translation, any of which could alter phenotype, rendering the synonymous mutation non-silent. The substrate specificity of the tRNA to the rare codon can affect the timing of translation, and in turn the co-translational folding of the protein. This is reflected in the codon usage bias that is observed in many species. Mutations that cause the altered codon to produce an amino acid with similar functionality (e.g. a mutation producing leucine instead of isoleucine) are often classified as silent; if the properties of the amino acid are conserved, this mutation does not usually significantly affect protein function.
Because Fragile X is a mutation in the X chromosome, it affects both males and females. However, females, with two X chromosomes, can carry the condition silently, because the healthy X masks the affected one.
2021's limited series The Silent Sea is one of those overlooked gems, a harrowing clash of dystopian dread, claustrophobic ambiance, and gruesome horror thrills — and an 80% positive critical score on Rotten Tomatoes, to boot.
It is largely a silent disease that goes undetected for a dangerously long period. The gene mutation that causes the cancer disproportionately affects those of Asian descent ... his specific mutation.
) 'Silent' mutations found to have repercussions beyond their own gene ... Now, researchers from the University of Notre Dame are adding new evidence to the emerging concept that these silent mutations may have crucial consequences.
The trailer shows you possessing human beings and animals as you fight mutated monsters, with a particular emphasis on combat over creepy scares. Slitterhead is the next game from SilentHill and ...
... of mass gun ownership, while the second sticks a pair of moldering former stars in a tomb of a Los Angeles mansion to continue Sunset Boulevard’s mutating of silent film style into harsh grotesquerie.
SilentPredators is a 1999 horror thriller movie directed by Noel Nosseck. The movie follows the story of a small peaceful town that is thrown into chaos by a silent, deadly threat of mutated rattlesnakes ... The post Silent Predators Streaming.
"It's a warzone," one teacher jokes when asked how his new first grade class is going, but he's right, and the way Yori is treated by his classmates as others stand by and silently watch is uncomfortable to watch.
Biophysical and structural analysis techniques are employed to understand the interaction mechanisms between silent Fc antibodies and Fcγ receptors or C1q, facilitating the optimization of mutation designs.
In the germline, where mutations can be passed on to offspring, systems are known to keep transposons transcriptionally silent and prevent their excessive activity.
In chronically infected people, the virus silently tests and eventually retains many mutations that help it avoid immunity and survive in that person ... SARS-CoV-2 continues to have a very high rate of mutation.
In chronically infected people, the virus silently tests and eventually retains many mutations that help it avoid immunity and survive in that person ... SARS-CoV-2 continues to have a very high rate of mutation.
The authors of the report added that “any new or nascent outbreak may have potential to go global” if it is able to silently infect and evolve in humans.Rapid mutation.