In genetics, a silencer is a DNA sequence capable of binding transcription regulation factors, called repressors. DNA contains genes and provides the template to produce messenger RNA (mRNA). That mRNA is then translated into proteins that activate or inactivate gene expression in cells. When a repressor protein binds to the silencer region of DNA, RNA polymerase—the enzyme that transcribes DNA into RNA—is prevented from binding to the promoter region. With the transcription of DNA into RNA blocked, the translation of RNA into proteins is impossible. Thus, silencers prevent genes from being expressed as proteins.
RNA polymerase, a DNA-dependent enzyme, transcribes the DNA sequences, called nucleotides, in the 3' to 5' direction while the complementary RNA is synthesized in the 5' to 3' direction. RNA is similar to DNA, except that RNA contains uracil, instead of thymine, which forms a base pair with adenine. An important region for the activity of gene repression and expression found in RNA is the 3' untranslated region. This is a region on the 3' terminus of RNA that will not be translated to protein but includes many regulatory regions.
This is a list of characters appearing in the Origin SystemsCrusader games. Interaction between the player and these characters usually takes place through a FMV cutscene playing, therefore each character's description is also accompanied by the name of the actor/actress portraying him/her.
Resistance characters
The Captain
The Captain is a Silencer, a fictional type of soldier in the Crusader games, and the silent player-controlledprotagonist of the series, introduced in the introduction movie of Crusader - No Remorse. No name is ever given and it is unknown if the character is male or female, with even the Vetron in the intro movie identifying him as "???" despite successfully discerning the names of his squadmates. The Captain receives two nicknames in the game, "Tin Man" and "Red". The Captain was once a member of the WEC Silencer Corps before defecting. His origins are unknown. According to the game manual, Silencers are picked out in their adolescent years and recruited for life. They undergo rigorous training and are trained to be the ultimate soldier. He is distinguished by his red armor. During the course of events of Crusader - No Remorse, the player finds out that the Captain, and other Silencers, are possibly the result of genetic engineering and cloning. The Captain is shown joining the Resistance in the year 2196, after an attack on his team by a WEC Vetron for failing to carry out orders. The Captain joins Echo Base and performs several missions including sabotage, assassination, espionage and intelligence. At the end of the game, the Captain is tasked to destroy the WEC's new orbital space station, the Vigilance Platform.
DNA² was adapted into a 12-episode anime television series which ran on Nippon Television from October 7, 1994 to December 23, 1994. This was followed by a three-episode anime original video animation (OVA) in 1995. Produced by Madhouse and Studio Deen, the anime series was directed by Jun'ichi Sakata, whereas the character designer and animation director for the series was Kumiko Takahashi. DNA² has been broadcast in Japan by Animax, which has also aired the series across its respective networks worldwide, including its English-language networks in Southeast Asia and South Asia. All 15 episodes were licensed in North America by Central Park Media until their closing in 2009. The five volumes and box set are out-of-print. Discotek Media has since re-licensed the series for a DVD release in 2014.
DNA2.0 was founded in 2003, in Menlo Park, California. The company is privately held and continues to have all research, development and production in Menlo Park, California. It began and continues as a gene synthesis and protein engineering provider to academia, government and the pharmaceutical, chemical, agricultural and biotechnology industries. Gene Synthesis rapidly replaced molecular cloning for many academic and corporate labs, as "foundries for the biotechnology age" allowing made-to-order genes for biological research.
DNA2.0 was featured on the PBS show Nova ScienceNow to show how genes are created synthetically in a lab. In 2008, the company supplied some of the DNA stretches used to create a synthetic bacterial genome.Dan Rather Reports included DNA2.0 in their episode on Synthetic Biology and how it is solving "some of the most important problems facing the world."
In 2009, The Scientist named the codon design algorithms (now tradmarked as GeneGPS) developed by DNA2.0 as one of the Top 10 Innovations of the year for Life Sciences. DNA2.0 developed the Electra Vector System, a universal cloning system that utilizes the type IIS restriction enzyme SapI and T4 DNA ligase in a single-tube reaction. DNA2.0 has made some molecular components, such as synthetic fluorescent proteins, available in open-access collections of DNA parts (BioBricks Foundation). DNA2.0 is a founding member of the International Gene Synthesis Consortium (IGSC) to promote biosecurity in the gene-synthesis industry. There are over 1,100 published scientific articles using DNA2.0 products and/or services, of which 43 include company employees as an author(s).
Go! Pop! Bang! is the debut studio album by American rapper Rye Rye. It was released on N.E.E.T. Recordings, an imprint of Interscope Records. The album was originally scheduled for release in 2009, but it has since been delayed several times, due to a pregnancy and label issues. It was eventually released on May 15, 2012, with a deluxe version available on iTunes. The album features several artists including M.I.A., Akon, Tyga, Robyn, and Porcelain Black. Production credits are given to M.I.A., The Neptunes, Mr. Bangladesh, and RedOne. The variety of styles brought from each producer was praised by critics.
Authorities were running DNA and fingerprint analysis on items found nearby, including a water bottle, that they believe the suspect may have discarded, the official was quoted as saying.
From that point you canvass the area, see what cameras are there, then pull footage and try to match it to the suspect.” GPSTracking, ballistics and DNA testing ... DNA evidence has been recovered from those items, sources said.
Pausch at Vilnius University, working alongside an international team, uncovered how cells use a specific system to locate and silence unwanted DNA... New CRISPR system for gene silencing doesn't rely on ...
Former NFL star Clark said 'there is something that he is missing in his intangible DNA' ...Bill Belichick breaks silence on Jets' 'puzzling' firing of RobertSaleh.
Like DNA, RNA is a form of genetic material made from individual nucleotides linked into chains ... Rather than translating DNA to proteins, they instead can bind to protein-coding RNAs to silence genes ... MicroRNA can silence genes by binding to mRNA.
Hardin CountyCircuit Judge J ... The body of Bobo, 20, was found more than three years later, ending a massive search by authorities and her family ... Then just dead silence for just a second.". Investigators found no DNA evidence connecting Adams to Bobo.
For decades, scientists thought that vertebrates had only one type of epigenetic modification on DNA called cytosine methylation, which is associated with gene silencing ... the amount of 5fC on the DNA.
laws ... Two of the automatic rifles contain traces of Goudreau's DNA, while silencers, night-vision goggles and other defense equipment bear serial numbers matching those purchased by Goudreau and his Melbourne, Florida-based security firm Silvercorp ... .
The solution to the structure and replication of DNA reinforced this ... The way genes can be silenced or activated by environmental conditions through epigenetics forms one example of this more nuanced picture, but others are less well understood.
They also similarly silenced the gene for promyelocytic leukemia (PML) protein, which—when contained in tiny, dense spheres called nuclear bodies—serves as an anchor and organizing point for many ...
Gender issues, post-war traumas, domestic violence, and silence around it. Well-made documentaries have the power to trigger those debates." Documentaries are also part of the SFF’s DNA, she says, ...
... aging is DNA methylation ... Methylation involves the attachment of methyl groups, composed of one carbon atom and three hydrogen atoms, to the DNA, which has the effect of silencing its expression.
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell... The role of Mrc1 in DNA replication ... replication of DNA.
Nothing illustrates the power of DNA to break through the lies and silence that surround so many family stories as in the case of John Portmann ...All that changed with a DNA test in ...
