Progeria (pronunciation: /proʊˈdʒɪəriə/) (Hutchinson–Gilford progeria syndrome,HGPS, progeria syndrome) is an extremely rare genetic disorder wherein symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. The word progeria comes from the Greek words "pro" (πρό), meaning "before" or "premature", and "gēras" (γῆρας), meaning "old age". The disorder has a very low incidence rate, occurring in an estimated 1 per 8million live births. Those born with progeria typically live to their mid teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS).
Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson–Gilford progeria syndrome.
Part 1: Barbara Walters goes inside families of kids who are eight but look eighty.
published: 20 Jan 2013
Progeria Has Taken My Teeth But Not My Smile | BORN DIFFERENT
SUBSCRIBE to Truly: http://bit.ly/Oc61Hj
A WOMAN who has been described as a medical anomaly has lost her hair and teeth but not her joyful spirit. Tiffany Wedekind, 43, from Columbus, Ohio, has progeria - a rapid ageing disease with an expected life expectancy of 13 years. Tiffany’s mum has the disease as did her brother, Chad, who passed away eight years ago. She has now lost her hair and her teeth as a result of the disease but is determined to continue living her life to the fullest.
Follow Tiffany here:
https://www.instagram.com/tenacioustiffany614/
Videographer: Max Rodriguez
Producers: Martha Hewett, Kim Nguyen
Editor: Alex Lubetkin
Click here to follow your favourite Truly shows on Instagram!
Truly - https://www.instagram.com/trulyshow
Born Different - https://www.instagram.c...
published: 06 Oct 2020
Adalia Rose (Progeria)
Adalia Rose is diagnosed with progeria, a rare genetic condition that results in accelerated aging.
She has decided to ignore the haters and shine as bright as possible. Now ten years old, Adalia brings joy to each person that is willing to accept her unique abilities.
Follow Adalia at https://www.youtube.com/user/TeamAdaliaRose
Join our community of 1.5 million on FB at http://www.facebook.com/specialbooksbokosbyspecialkids
Behind the scenes pics on IG at http://www.instagram.com/specialbookbyspecialkids
SBSK updates on twitter at: http://www.Twitter.com/chrisulmer
published: 05 Jun 2017
Tenacious Tiffany: Living With Progeria And Larger Than Life | Studio 10
Subscribe now for more! https://youtube.com/c/Studio10au
Check out our home on 10play: https://10play.com.au/studio10
Tiffany Wedekind has progeria, a disease that causes her to age eight times faster than the rest of us. It's so rare, it affects fewer than 200 people in the whole world. But that hasn’t stopped her spreading happiness and positivity in the world.
Start your day with a dose of sunshine 🌞 and join the feelgood fun 🙌 with Sarah Harris and Tristan MacManus every weekday from 8am on Network 10 Australia!
Facebook: https://facebook.com/studio10au
Twitter: https://twitter.com/Studio10au (@studio10au)
Instagram: https://www.instagram.com/studio10au (@studio10au)
#Studio10 #Network10 #MorningTV
published: 02 Jul 2021
Brothers with Progeria (Nathan and Bennett)
Nathan and Bennett are diagnosed with a rare form of progeria that affects only five people in the world. They also happen to be brothers.
The two wish that others would look past this condition that makes them appear older to see they are just normal kids. Until then the brothers find comfort that they have each other.
Follow Nathan and Bennett at http://www.youtube.com/channel/UCdagpyf0tuWoCCYEZf0FoGA.
Follow SBSK on Facebook at http://www.facebook.com/specialbooksbyspecialkids
Instagram:http://www.instagram.com/specialbooksbyspecialkids
Twitter: http://www.Twitter.com/chrisSBSK
published: 10 Oct 2017
Base editing successfully treats progeria in mice
January 11, 2021
A team led by researchers from the Broad Institute of MIT and Harvard, the National Institutes of Health, and Vanderbilt University Medical Center has used base editing, a recently developed form of gene editing, to rescue disease symptoms and lifespan in mice that have Hutchinson-Gilford progeria syndrome.
Co-senior authors on the study include David Liu, director of the Merkin Institute of Transformative Technologies in Healthcare at the Broad Institute, professor at Harvard University, and investigator with the Howard Hughes Medical Institute, Francis Collins, director of the National Institutes of Health and senior investigator at the National Human Genome Research Institute, and Jonathan Brown, assistant professor of medicine in the Division of Cardiovascular Medici...
published: 11 Jan 2021
Race Against Time | Families with kids diagnosed with aging disease remain positive | Sunday Night
Adalia and Meghan are two beautiful and courageous young girls who are growing up way too fast. Both have a rare and fatal genetic condition called Progeria, a disease that causes rapid ageing – 10-times faster than normal. Their life expectancy is very short, usually only into the mid-teens. But, as Sunday Night’s Steve Pennells reports, they are making every second of their short lives count. And the good news is, there’s now hope for a cure.
This story originally aired on the 21st October 2018. Sadly Adalia passed away on January 12, 2022.
Read more - https://7news.com.au/sunday-night/every-day-we-try-to-make-the-best-of-it-families-with-children-diagnosed-with-aging-disease-remain-positive-of-a-cure-c-14624
published: 22 Oct 2018
Progeria Syndrome Explained | How it is caused?
Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teen to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome.
Learn more about LASIK Eye Surgery:- https://youtu.be/fVNG3-Zbamc
Share, Support, Subscribe!!!
Subscribe Here for free:-https://goo.gl/XiZVPQ
Youtube:-http://www.yout...
SUBSCRIBE to Truly: http://bit.ly/Oc61Hj
A WOMAN who has been described as a medical anomaly has lost her hair and teeth but not her joyful spirit. Tiffany Wed...
SUBSCRIBE to Truly: http://bit.ly/Oc61Hj
A WOMAN who has been described as a medical anomaly has lost her hair and teeth but not her joyful spirit. Tiffany Wedekind, 43, from Columbus, Ohio, has progeria - a rapid ageing disease with an expected life expectancy of 13 years. Tiffany’s mum has the disease as did her brother, Chad, who passed away eight years ago. She has now lost her hair and her teeth as a result of the disease but is determined to continue living her life to the fullest.
Follow Tiffany here:
https://www.instagram.com/tenacioustiffany614/
Videographer: Max Rodriguez
Producers: Martha Hewett, Kim Nguyen
Editor: Alex Lubetkin
Click here to follow your favourite Truly shows on Instagram!
Truly - https://www.instagram.com/trulyshow
Born Different - https://www.instagram.com/borndifferentshow/
Shake My Beauty - https://www.instagram.com/shakemybeauty/
Hooked On The Look - https://www.instagram.com/hookedonthelookshow/
Beastly - https://www.instagram.com/beastlyshow/
Ridiculous Rides - https://www.instagram.com/ridiculousridesshow/
Dog Dynasty - https://www.instagram.com/dogdynastyshow/
For more amazing content, click here!
Beastly: https://www.youtube.com/channel/UC9LxuffQCm_Z4KBCoXZvSHA
Barcroft Cars: https://www.youtube.com/user/BarcroftCars/featured
SUBSCRIBE to Truly: http://bit.ly/Oc61Hj
A WOMAN who has been described as a medical anomaly has lost her hair and teeth but not her joyful spirit. Tiffany Wedekind, 43, from Columbus, Ohio, has progeria - a rapid ageing disease with an expected life expectancy of 13 years. Tiffany’s mum has the disease as did her brother, Chad, who passed away eight years ago. She has now lost her hair and her teeth as a result of the disease but is determined to continue living her life to the fullest.
Follow Tiffany here:
https://www.instagram.com/tenacioustiffany614/
Videographer: Max Rodriguez
Producers: Martha Hewett, Kim Nguyen
Editor: Alex Lubetkin
Click here to follow your favourite Truly shows on Instagram!
Truly - https://www.instagram.com/trulyshow
Born Different - https://www.instagram.com/borndifferentshow/
Shake My Beauty - https://www.instagram.com/shakemybeauty/
Hooked On The Look - https://www.instagram.com/hookedonthelookshow/
Beastly - https://www.instagram.com/beastlyshow/
Ridiculous Rides - https://www.instagram.com/ridiculousridesshow/
Dog Dynasty - https://www.instagram.com/dogdynastyshow/
For more amazing content, click here!
Beastly: https://www.youtube.com/channel/UC9LxuffQCm_Z4KBCoXZvSHA
Barcroft Cars: https://www.youtube.com/user/BarcroftCars/featured
Adalia Rose is diagnosed with progeria, a rare genetic condition that results in accelerated aging.
She has decided to ignore the haters and shine as bright as...
Adalia Rose is diagnosed with progeria, a rare genetic condition that results in accelerated aging.
She has decided to ignore the haters and shine as bright as possible. Now ten years old, Adalia brings joy to each person that is willing to accept her unique abilities.
Follow Adalia at https://www.youtube.com/user/TeamAdaliaRose
Join our community of 1.5 million on FB at http://www.facebook.com/specialbooksbokosbyspecialkids
Behind the scenes pics on IG at http://www.instagram.com/specialbookbyspecialkids
SBSK updates on twitter at: http://www.Twitter.com/chrisulmer
Adalia Rose is diagnosed with progeria, a rare genetic condition that results in accelerated aging.
She has decided to ignore the haters and shine as bright as possible. Now ten years old, Adalia brings joy to each person that is willing to accept her unique abilities.
Follow Adalia at https://www.youtube.com/user/TeamAdaliaRose
Join our community of 1.5 million on FB at http://www.facebook.com/specialbooksbokosbyspecialkids
Behind the scenes pics on IG at http://www.instagram.com/specialbookbyspecialkids
SBSK updates on twitter at: http://www.Twitter.com/chrisulmer
Subscribe now for more! https://youtube.com/c/Studio10au
Check out our home on 10play: https://10play.com.au/studio10
Tiffany Wedekind has progeria, a disease t...
Subscribe now for more! https://youtube.com/c/Studio10au
Check out our home on 10play: https://10play.com.au/studio10
Tiffany Wedekind has progeria, a disease that causes her to age eight times faster than the rest of us. It's so rare, it affects fewer than 200 people in the whole world. But that hasn’t stopped her spreading happiness and positivity in the world.
Start your day with a dose of sunshine 🌞 and join the feelgood fun 🙌 with Sarah Harris and Tristan MacManus every weekday from 8am on Network 10 Australia!
Facebook: https://facebook.com/studio10au
Twitter: https://twitter.com/Studio10au (@studio10au)
Instagram: https://www.instagram.com/studio10au (@studio10au)
#Studio10 #Network10 #MorningTV
Subscribe now for more! https://youtube.com/c/Studio10au
Check out our home on 10play: https://10play.com.au/studio10
Tiffany Wedekind has progeria, a disease that causes her to age eight times faster than the rest of us. It's so rare, it affects fewer than 200 people in the whole world. But that hasn’t stopped her spreading happiness and positivity in the world.
Start your day with a dose of sunshine 🌞 and join the feelgood fun 🙌 with Sarah Harris and Tristan MacManus every weekday from 8am on Network 10 Australia!
Facebook: https://facebook.com/studio10au
Twitter: https://twitter.com/Studio10au (@studio10au)
Instagram: https://www.instagram.com/studio10au (@studio10au)
#Studio10 #Network10 #MorningTV
Nathan and Bennett are diagnosed with a rare form of progeria that affects only five people in the world. They also happen to be brothers.
The two wish that ot...
Nathan and Bennett are diagnosed with a rare form of progeria that affects only five people in the world. They also happen to be brothers.
The two wish that others would look past this condition that makes them appear older to see they are just normal kids. Until then the brothers find comfort that they have each other.
Follow Nathan and Bennett at http://www.youtube.com/channel/UCdagpyf0tuWoCCYEZf0FoGA.
Follow SBSK on Facebook at http://www.facebook.com/specialbooksbyspecialkids
Instagram:http://www.instagram.com/specialbooksbyspecialkids
Twitter: http://www.Twitter.com/chrisSBSK
Nathan and Bennett are diagnosed with a rare form of progeria that affects only five people in the world. They also happen to be brothers.
The two wish that others would look past this condition that makes them appear older to see they are just normal kids. Until then the brothers find comfort that they have each other.
Follow Nathan and Bennett at http://www.youtube.com/channel/UCdagpyf0tuWoCCYEZf0FoGA.
Follow SBSK on Facebook at http://www.facebook.com/specialbooksbyspecialkids
Instagram:http://www.instagram.com/specialbooksbyspecialkids
Twitter: http://www.Twitter.com/chrisSBSK
January 11, 2021
A team led by researchers from the Broad Institute of MIT and Harvard, the National Institutes of Health, and Vanderbilt University Medical Ce...
January 11, 2021
A team led by researchers from the Broad Institute of MIT and Harvard, the National Institutes of Health, and Vanderbilt University Medical Center has used base editing, a recently developed form of gene editing, to rescue disease symptoms and lifespan in mice that have Hutchinson-Gilford progeria syndrome.
Co-senior authors on the study include David Liu, director of the Merkin Institute of Transformative Technologies in Healthcare at the Broad Institute, professor at Harvard University, and investigator with the Howard Hughes Medical Institute, Francis Collins, director of the National Institutes of Health and senior investigator at the National Human Genome Research Institute, and Jonathan Brown, assistant professor of medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center.
Learn more at broad.io/progeria.
Paper cited:
Koblan LW, Erdos MR, et al. In vivo adenine base editing rescues Hutchinson-Gilford progeria syndrome. Nature. Online January 6, 2021. DOI: 10.1038/s41586-020-03086-7
For more information visit: https://www.broadinstitute.org
Copyright Broad Institute, 2021. All rights reserved.
January 11, 2021
A team led by researchers from the Broad Institute of MIT and Harvard, the National Institutes of Health, and Vanderbilt University Medical Center has used base editing, a recently developed form of gene editing, to rescue disease symptoms and lifespan in mice that have Hutchinson-Gilford progeria syndrome.
Co-senior authors on the study include David Liu, director of the Merkin Institute of Transformative Technologies in Healthcare at the Broad Institute, professor at Harvard University, and investigator with the Howard Hughes Medical Institute, Francis Collins, director of the National Institutes of Health and senior investigator at the National Human Genome Research Institute, and Jonathan Brown, assistant professor of medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center.
Learn more at broad.io/progeria.
Paper cited:
Koblan LW, Erdos MR, et al. In vivo adenine base editing rescues Hutchinson-Gilford progeria syndrome. Nature. Online January 6, 2021. DOI: 10.1038/s41586-020-03086-7
For more information visit: https://www.broadinstitute.org
Copyright Broad Institute, 2021. All rights reserved.
Adalia and Meghan are two beautiful and courageous young girls who are growing up way too fast. Both have a rare and fatal genetic condition called Progeria, a ...
Adalia and Meghan are two beautiful and courageous young girls who are growing up way too fast. Both have a rare and fatal genetic condition called Progeria, a disease that causes rapid ageing – 10-times faster than normal. Their life expectancy is very short, usually only into the mid-teens. But, as Sunday Night’s Steve Pennells reports, they are making every second of their short lives count. And the good news is, there’s now hope for a cure.
This story originally aired on the 21st October 2018. Sadly Adalia passed away on January 12, 2022.
Read more - https://7news.com.au/sunday-night/every-day-we-try-to-make-the-best-of-it-families-with-children-diagnosed-with-aging-disease-remain-positive-of-a-cure-c-14624
Adalia and Meghan are two beautiful and courageous young girls who are growing up way too fast. Both have a rare and fatal genetic condition called Progeria, a disease that causes rapid ageing – 10-times faster than normal. Their life expectancy is very short, usually only into the mid-teens. But, as Sunday Night’s Steve Pennells reports, they are making every second of their short lives count. And the good news is, there’s now hope for a cure.
This story originally aired on the 21st October 2018. Sadly Adalia passed away on January 12, 2022.
Read more - https://7news.com.au/sunday-night/every-day-we-try-to-make-the-best-of-it-families-with-children-diagnosed-with-aging-disease-remain-positive-of-a-cure-c-14624
Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is ...
Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teen to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome.
Learn more about LASIK Eye Surgery:- https://youtu.be/fVNG3-Zbamc
Share, Support, Subscribe!!!
Subscribe Here for free:-https://goo.gl/XiZVPQ
Youtube:-http://www.youtube.com/c/TopTechInformation
Twitter:-https://twitter.com/TTI_TopTechInfo
Facebook Page:-https://www.facebook.com/TTISATYAM27/
Facebook Myself:-https://www.facebook.com/11satyam
Instagram:-https://www.instagram.com/toptechinformation/
Google Plus:-https://goo.gl/X9qKve
About:- Top Tech Information is a Youtube Channel, where you will find science and technology videos in Hindi. New video is posted everyday
__________________________________________________________________________________________________________________________________
Music Information:-
Title:-TULE - Fearless [NCS Release]
Checkout the song on NCS Youtube Channel:-
https://goo.gl/Y8wdQw
Image Sources:
https://commons.wikimedia.org/wiki/File:Quadre_comparatiu.JPG
https://commons.wikimedia.org/wiki/File:Hutchinson-Gilford_Progeria_Syndrome.png
https://commons.wikimedia.org/wiki/File:Autosomal_dominant_-_en.svg
https://www.flickr.com/photos/tillyholland/15469586570
https://commons.wikimedia.org/wiki/File:Jonathan_Hutchinson.jpg
https://commons.wikimedia.org/wiki/File:Diagram_human_cell_nucleus.svg
https://commons.wikimedia.org/wiki/File:Human_Heart_and_Circulatory_System.png
https://commons.wikimedia.org/wiki/File:Leon_Botha.jpg
Thanks to Pixabay for providing other free stock images and videos that are used in the video under creative commons (CC0) in public domain category.
Pixabay:-https://pixabay.com/
Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teen to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome.
Learn more about LASIK Eye Surgery:- https://youtu.be/fVNG3-Zbamc
Share, Support, Subscribe!!!
Subscribe Here for free:-https://goo.gl/XiZVPQ
Youtube:-http://www.youtube.com/c/TopTechInformation
Twitter:-https://twitter.com/TTI_TopTechInfo
Facebook Page:-https://www.facebook.com/TTISATYAM27/
Facebook Myself:-https://www.facebook.com/11satyam
Instagram:-https://www.instagram.com/toptechinformation/
Google Plus:-https://goo.gl/X9qKve
About:- Top Tech Information is a Youtube Channel, where you will find science and technology videos in Hindi. New video is posted everyday
__________________________________________________________________________________________________________________________________
Music Information:-
Title:-TULE - Fearless [NCS Release]
Checkout the song on NCS Youtube Channel:-
https://goo.gl/Y8wdQw
Image Sources:
https://commons.wikimedia.org/wiki/File:Quadre_comparatiu.JPG
https://commons.wikimedia.org/wiki/File:Hutchinson-Gilford_Progeria_Syndrome.png
https://commons.wikimedia.org/wiki/File:Autosomal_dominant_-_en.svg
https://www.flickr.com/photos/tillyholland/15469586570
https://commons.wikimedia.org/wiki/File:Jonathan_Hutchinson.jpg
https://commons.wikimedia.org/wiki/File:Diagram_human_cell_nucleus.svg
https://commons.wikimedia.org/wiki/File:Human_Heart_and_Circulatory_System.png
https://commons.wikimedia.org/wiki/File:Leon_Botha.jpg
Thanks to Pixabay for providing other free stock images and videos that are used in the video under creative commons (CC0) in public domain category.
Pixabay:-https://pixabay.com/
SUBSCRIBE to Truly: http://bit.ly/Oc61Hj
A WOMAN who has been described as a medical anomaly has lost her hair and teeth but not her joyful spirit. Tiffany Wedekind, 43, from Columbus, Ohio, has progeria - a rapid ageing disease with an expected life expectancy of 13 years. Tiffany’s mum has the disease as did her brother, Chad, who passed away eight years ago. She has now lost her hair and her teeth as a result of the disease but is determined to continue living her life to the fullest.
Follow Tiffany here:
https://www.instagram.com/tenacioustiffany614/
Videographer: Max Rodriguez
Producers: Martha Hewett, Kim Nguyen
Editor: Alex Lubetkin
Click here to follow your favourite Truly shows on Instagram!
Truly - https://www.instagram.com/trulyshow
Born Different - https://www.instagram.com/borndifferentshow/
Shake My Beauty - https://www.instagram.com/shakemybeauty/
Hooked On The Look - https://www.instagram.com/hookedonthelookshow/
Beastly - https://www.instagram.com/beastlyshow/
Ridiculous Rides - https://www.instagram.com/ridiculousridesshow/
Dog Dynasty - https://www.instagram.com/dogdynastyshow/
For more amazing content, click here!
Beastly: https://www.youtube.com/channel/UC9LxuffQCm_Z4KBCoXZvSHA
Barcroft Cars: https://www.youtube.com/user/BarcroftCars/featured
Adalia Rose is diagnosed with progeria, a rare genetic condition that results in accelerated aging.
She has decided to ignore the haters and shine as bright as possible. Now ten years old, Adalia brings joy to each person that is willing to accept her unique abilities.
Follow Adalia at https://www.youtube.com/user/TeamAdaliaRose
Join our community of 1.5 million on FB at http://www.facebook.com/specialbooksbokosbyspecialkids
Behind the scenes pics on IG at http://www.instagram.com/specialbookbyspecialkids
SBSK updates on twitter at: http://www.Twitter.com/chrisulmer
Subscribe now for more! https://youtube.com/c/Studio10au
Check out our home on 10play: https://10play.com.au/studio10
Tiffany Wedekind has progeria, a disease that causes her to age eight times faster than the rest of us. It's so rare, it affects fewer than 200 people in the whole world. But that hasn’t stopped her spreading happiness and positivity in the world.
Start your day with a dose of sunshine 🌞 and join the feelgood fun 🙌 with Sarah Harris and Tristan MacManus every weekday from 8am on Network 10 Australia!
Facebook: https://facebook.com/studio10au
Twitter: https://twitter.com/Studio10au (@studio10au)
Instagram: https://www.instagram.com/studio10au (@studio10au)
#Studio10 #Network10 #MorningTV
Nathan and Bennett are diagnosed with a rare form of progeria that affects only five people in the world. They also happen to be brothers.
The two wish that others would look past this condition that makes them appear older to see they are just normal kids. Until then the brothers find comfort that they have each other.
Follow Nathan and Bennett at http://www.youtube.com/channel/UCdagpyf0tuWoCCYEZf0FoGA.
Follow SBSK on Facebook at http://www.facebook.com/specialbooksbyspecialkids
Instagram:http://www.instagram.com/specialbooksbyspecialkids
Twitter: http://www.Twitter.com/chrisSBSK
January 11, 2021
A team led by researchers from the Broad Institute of MIT and Harvard, the National Institutes of Health, and Vanderbilt University Medical Center has used base editing, a recently developed form of gene editing, to rescue disease symptoms and lifespan in mice that have Hutchinson-Gilford progeria syndrome.
Co-senior authors on the study include David Liu, director of the Merkin Institute of Transformative Technologies in Healthcare at the Broad Institute, professor at Harvard University, and investigator with the Howard Hughes Medical Institute, Francis Collins, director of the National Institutes of Health and senior investigator at the National Human Genome Research Institute, and Jonathan Brown, assistant professor of medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center.
Learn more at broad.io/progeria.
Paper cited:
Koblan LW, Erdos MR, et al. In vivo adenine base editing rescues Hutchinson-Gilford progeria syndrome. Nature. Online January 6, 2021. DOI: 10.1038/s41586-020-03086-7
For more information visit: https://www.broadinstitute.org
Copyright Broad Institute, 2021. All rights reserved.
Adalia and Meghan are two beautiful and courageous young girls who are growing up way too fast. Both have a rare and fatal genetic condition called Progeria, a disease that causes rapid ageing – 10-times faster than normal. Their life expectancy is very short, usually only into the mid-teens. But, as Sunday Night’s Steve Pennells reports, they are making every second of their short lives count. And the good news is, there’s now hope for a cure.
This story originally aired on the 21st October 2018. Sadly Adalia passed away on January 12, 2022.
Read more - https://7news.com.au/sunday-night/every-day-we-try-to-make-the-best-of-it-families-with-children-diagnosed-with-aging-disease-remain-positive-of-a-cure-c-14624
Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. Those born with progeria typically live to their mid-teen to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome.
Learn more about LASIK Eye Surgery:- https://youtu.be/fVNG3-Zbamc
Share, Support, Subscribe!!!
Subscribe Here for free:-https://goo.gl/XiZVPQ
Youtube:-http://www.youtube.com/c/TopTechInformation
Twitter:-https://twitter.com/TTI_TopTechInfo
Facebook Page:-https://www.facebook.com/TTISATYAM27/
Facebook Myself:-https://www.facebook.com/11satyam
Instagram:-https://www.instagram.com/toptechinformation/
Google Plus:-https://goo.gl/X9qKve
About:- Top Tech Information is a Youtube Channel, where you will find science and technology videos in Hindi. New video is posted everyday
__________________________________________________________________________________________________________________________________
Music Information:-
Title:-TULE - Fearless [NCS Release]
Checkout the song on NCS Youtube Channel:-
https://goo.gl/Y8wdQw
Image Sources:
https://commons.wikimedia.org/wiki/File:Quadre_comparatiu.JPG
https://commons.wikimedia.org/wiki/File:Hutchinson-Gilford_Progeria_Syndrome.png
https://commons.wikimedia.org/wiki/File:Autosomal_dominant_-_en.svg
https://www.flickr.com/photos/tillyholland/15469586570
https://commons.wikimedia.org/wiki/File:Jonathan_Hutchinson.jpg
https://commons.wikimedia.org/wiki/File:Diagram_human_cell_nucleus.svg
https://commons.wikimedia.org/wiki/File:Human_Heart_and_Circulatory_System.png
https://commons.wikimedia.org/wiki/File:Leon_Botha.jpg
Thanks to Pixabay for providing other free stock images and videos that are used in the video under creative commons (CC0) in public domain category.
Pixabay:-https://pixabay.com/
Progeria (pronunciation: /proʊˈdʒɪəriə/) (Hutchinson–Gilford progeria syndrome,HGPS, progeria syndrome) is an extremely rare genetic disorder wherein symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. The word progeria comes from the Greek words "pro" (πρό), meaning "before" or "premature", and "gēras" (γῆρας), meaning "old age". The disorder has a very low incidence rate, occurring in an estimated 1 per 8million live births. Those born with progeria typically live to their mid teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome (HGPS).
Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson–Gilford progeria syndrome.
It is the shanty in the dear park the hide and seek till after dark the talks we had at picked fences create the blueprints in my heart of the way we are the way we are... I see them sliding down on brook bridge in tiny boots on icy streets the gang we had was so almighty tell me the blueprints of my heart I wonder where they are... the way we are