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2-Minute Neuroscience: Long-Term Depression (LTD)
Long-term depression, or LTD, is a process by which synaptic connections between neurons are weakened. Although the functions of LTD are not completely understood, it may be important to memory formation---perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation (LTP). In this video, I discuss the best understood mechanism underlying LTD, which involves AMPA and NMDA glutamate receptors.
TRANSCRIPT:
Welcome to 2 minute neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less. In this installment I will discuss long-term depression, or LTD.
LTD is a process by which synaptic connections between neurons become weaker. It is the opposing process to long-term potentiation. Although the functions of LTD are ...
published: 03 Aug 2017
-
5 Signs You Have Chronic Depression
When most of us think of depression, we often think of major depressive disorder (MDD), where depression symptoms occur in episodes ranging from weeks to months. However, did you know that depression can persist for longer periods of time, where symptoms last over the course of two or more years without any relief at all? Chronic depression is also known as persistent depressive disorder or PDD, and is defined by a continuous depressed mood that occurs for at least two years. In today’s video, we will address the signs and symptoms of chronic depression.
DISCLAIMER: This video is for educational purposes only and is not meant to be used for diagnostic purposes. If you believe that you may be suffering from persistent depressive disorder, we encourage you to seek help from mental health p...
published: 25 Aug 2022
-
Learning to Live with Clinical Depression | Angelica Galluzzo | TEDxWesternU
Angelica shares how living with depression has impacted her life. Angelica Galluzzo is a mental health advocate, largely motivated by her own struggles with mental illness. After battling depression and suicidal ideation for many years, she became passionate about making an impact, using her voice to create positive change, and normalizing the struggles that many of us go through.
In 2021, she started her own podcast, called The Revolutionized Mind, with the goals of providing a safe space for people to share their stories, raising awareness about various mental illnesses, and learning how to embrace true authenticity.
Angelica graduated with an Honors Specialization in Psychology at Western University and has also completed her safeTALK, ASIST, and Mental Health First Aid certificatio...
published: 01 Mar 2023
-
How Depression Affects The Brain - Yale Medicine Explains
For more information on mental health or #YaleMedicine, visit: https://www.yalemedicine.org/conditions/topics/mental-health.
For many people, depression turns out to be one of the most disabling illnesses that we have in society. Despite the treatments that we have available, many people are not responding that well. It's a disorder that can be very disabling in society. It's also a disorder that has medical consequences. By understand the neurobiology of depression we hope to be able more to find the right treatment for the patient suffering from this disease. The current standard of care for the treatment of depression is based on what we call the monoamine deficiency hypothesis. Essentially, presuming that one of three neurotransmitters in the brain is deficient or underactive. But th...
published: 26 May 2021
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How I overcame depression by just sitting around | Jonathan Schoenmaker | TEDxDelft
Jonathan Schoenmaker struggled with depression. With the best intentions, his friends and family would try to help by saying all the wrong things. In the end, Jonathan found the best way for him to experience happiness. As it turned out, what he needed most wasn't what everyone told him it would be. Jonathan Schoenmaker: a 20 year old Dutch physics student at the TU Delft and winner of the TEDx Delft Award. Jonathan’s talk is about his experience of suffering years of depression and the steps one can actually take to try and help people with this serious disease This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
published: 10 May 2018
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"I'm Fine" - Learning To Live With Depression | Jake Tyler | TEDxBrighton
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of online followers as he goes and attracting the attention of both the BBC and the Royal Family. In this talk, Jake shares his insights into living with depression and how connecting to and opening up to a wide online community has affected his relationship with depression.
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of onl...
published: 13 Feb 2018
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Jordan Peterson's Advice For People With Depression
12 Rules for Life: An Antidote to Chaos: https://amzn.to/39phlNc
Beyond Order: 12 More Rules for Life: https://amzn.to/3dgVHfl
Jordan Peterson shares his advice for people with depression. Watch this fantastic video until the end, you won't be disappointed. If you enjoyed, please be sure to like, subscribe, and share the video! 😀
Speaker: Jordan Peterson
Special Thanks To Jordan Peterson for allowing us to share!
YouTube: https:https://www.youtube.com/user/JordanPetersonVideos
Twitter: https://twitter.com/jordanbpeterson
Donate to support him:
Donation Link: https://www.jordanbpeterson.com/donate/
-----------------------------------------------------------------------
►Follow Motivation Ark:
Subscribe for new Motivational Videos every week: https://www.youtube.com/channel/UC9vLdyHatO...
published: 01 Mar 2021
-
The Road to Healing: How Long Will Depression Recovery Take?
In this video, we're answering the question: "How long will depression recovery take?"
We're talking about the journey of healing from depression, and the various factors that can influence how long the process will take.
We hope that this video is helpful as you embark on your own road to healing from depression. Thanks for watching!
#depression #cure
published: 17 Jul 2023
-
Understanding & Conquering Depression
This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical systems that are altered in depression: norepinephrine, serotonin and dopamine. I discuss genetic predispositions to depression and how stress, thyroid hormone and cortisol play a role in many forms of depression. I also discuss inflammation as a common feature of many depression symptoms. I review 8 specific science-supported protocols for treating and avoiding depression, including EPA fatty acids (which have been shown to rival certain prescription treatments), how exercise protects against depression, studies of creatine, adjusting dopamine balance and more...
published: 23 Aug 2021
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My Experience With Depression & How I Overcome It
Have you experience depression? What was your story? Are you looking for how to overcome depression?
VOICE: Amanda Silvera
Animator: Rina C.
YouTube Manager: Cindy Cheong
Have a story you would like to share? Email us at [email protected] with your stories.
#bedtimestories #depression
published: 05 Sep 2021
2:00
2-Minute Neuroscience: Long-Term Depression (LTD)
Long-term depression, or LTD, is a process by which synaptic connections between neurons are weakened. Although the functions of LTD are not completely understo...
Long-term depression, or LTD, is a process by which synaptic connections between neurons are weakened. Although the functions of LTD are not completely understood, it may be important to memory formation---perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation (LTP). In this video, I discuss the best understood mechanism underlying LTD, which involves AMPA and NMDA glutamate receptors.
TRANSCRIPT:
Welcome to 2 minute neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less. In this installment I will discuss long-term depression, or LTD.
LTD is a process by which synaptic connections between neurons become weaker. It is the opposing process to long-term potentiation. Although the functions of LTD are not completely understood, it’s thought to be important to memory formation, perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation.
There are several different mechanisms by which LTD may occur, but the best understood of them involves the same glutamate receptors involved in long-term potentiation: NMDA and AMPA receptors. NMDA receptors are typically blocked by a magnesium ion, which is only removed if the postsynaptic neuron becomes sufficiently depolarized as can occur through activation of the AMPA receptor; when the block is removed, calcium is able to flow into the neuron, causing further depolarization. While long-term potentiation typically occurs after brief but high-intensity stimulation of a post-synaptic neuron, LTD can be caused by prolonged low-intensity stimulation or stimulation that occurs after the firing of an action potential. With the type of modest stimulation that results in LTD, there is not enough depolarization to cause widespread removal of the magnesium blockage of the NMDA receptor. However, there is enough to cause some NMDA receptors to allow calcium into the cell. This low level of calcium is insufficient to activate the enzymes that facilitate long-term potentiation, but it is thought to activate a cellular cascade that causes the removal of AMPA receptors. This reduces the number of glutamate receptors on the postsynaptic neuron and weakens the synapse.
LTD may also result in other changes that decrease the strength of synapses, like a decrease in the amount of glutamate released from the presynaptic neuron, and it also can involve other receptors like metabotropic glutamate receptors or other neurotransmitter receptors altogether.
REFERENCE:
Kandel ER, Schwartz JH, Jessell TM 2000. Principles of Neural Science, 5th ed. McGraw-Hill, New York.
https://wn.com/2_Minute_Neuroscience_Long_Term_Depression_(Ltd)
Long-term depression, or LTD, is a process by which synaptic connections between neurons are weakened. Although the functions of LTD are not completely understood, it may be important to memory formation---perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation (LTP). In this video, I discuss the best understood mechanism underlying LTD, which involves AMPA and NMDA glutamate receptors.
TRANSCRIPT:
Welcome to 2 minute neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less. In this installment I will discuss long-term depression, or LTD.
LTD is a process by which synaptic connections between neurons become weaker. It is the opposing process to long-term potentiation. Although the functions of LTD are not completely understood, it’s thought to be important to memory formation, perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation.
There are several different mechanisms by which LTD may occur, but the best understood of them involves the same glutamate receptors involved in long-term potentiation: NMDA and AMPA receptors. NMDA receptors are typically blocked by a magnesium ion, which is only removed if the postsynaptic neuron becomes sufficiently depolarized as can occur through activation of the AMPA receptor; when the block is removed, calcium is able to flow into the neuron, causing further depolarization. While long-term potentiation typically occurs after brief but high-intensity stimulation of a post-synaptic neuron, LTD can be caused by prolonged low-intensity stimulation or stimulation that occurs after the firing of an action potential. With the type of modest stimulation that results in LTD, there is not enough depolarization to cause widespread removal of the magnesium blockage of the NMDA receptor. However, there is enough to cause some NMDA receptors to allow calcium into the cell. This low level of calcium is insufficient to activate the enzymes that facilitate long-term potentiation, but it is thought to activate a cellular cascade that causes the removal of AMPA receptors. This reduces the number of glutamate receptors on the postsynaptic neuron and weakens the synapse.
LTD may also result in other changes that decrease the strength of synapses, like a decrease in the amount of glutamate released from the presynaptic neuron, and it also can involve other receptors like metabotropic glutamate receptors or other neurotransmitter receptors altogether.
REFERENCE:
Kandel ER, Schwartz JH, Jessell TM 2000. Principles of Neural Science, 5th ed. McGraw-Hill, New York.
- published: 03 Aug 2017
- views: 179956
5:02
5 Signs You Have Chronic Depression
When most of us think of depression, we often think of major depressive disorder (MDD), where depression symptoms occur in episodes ranging from weeks to months...
When most of us think of depression, we often think of major depressive disorder (MDD), where depression symptoms occur in episodes ranging from weeks to months. However, did you know that depression can persist for longer periods of time, where symptoms last over the course of two or more years without any relief at all? Chronic depression is also known as persistent depressive disorder or PDD, and is defined by a continuous depressed mood that occurs for at least two years. In today’s video, we will address the signs and symptoms of chronic depression.
DISCLAIMER: This video is for educational purposes only and is not meant to be used for diagnostic purposes. If you believe that you may be suffering from persistent depressive disorder, we encourage you to seek help from mental health professionals
We also made a video on the signs you're depressed, not lazy: https://youtu.be/q8HRGiUeZwc
Writer: Max Feng
Script Editor: Vanessa Tao
Script Manager: Kelly Soong
VO: Amanda Silvera (www.youtube.com/amandasilvera)
Animator: AwesomeKickArt (www.instagram.com/awesomekickart)
YouTube Manager: Cindy Cheong
References:
Mayo Clinic Staff. (2018, December 8). Persistent depressive disorder (dysthymia). Mayo Clinic.
Retrieved from www.mayoclinic.org/diseases-conditions/
persistent-depressive-disorder/symptoms-causes/syc-20350929
Stiehl, C. (2018, May 4). The Difference Between Depression and Persistent Depressive Disorder, aka
Dysthymia. SELF. Retrieved from www.self.com/story/persistent-depressive-disorder-depression
Familydoctor.org Editorial Staff. (2020, March 31). Persistent Depressive Disorder (PDD).
familydoctor.org. Retrieved from familydoctor.org/condition/persistent-depressive-disorder/
Devash, M. (2020, February 18). Let's Talk About Chronic Depression. HealthCentral. www.healthcentral.com/condition/chronic-depression
https://wn.com/5_Signs_You_Have_Chronic_Depression
When most of us think of depression, we often think of major depressive disorder (MDD), where depression symptoms occur in episodes ranging from weeks to months. However, did you know that depression can persist for longer periods of time, where symptoms last over the course of two or more years without any relief at all? Chronic depression is also known as persistent depressive disorder or PDD, and is defined by a continuous depressed mood that occurs for at least two years. In today’s video, we will address the signs and symptoms of chronic depression.
DISCLAIMER: This video is for educational purposes only and is not meant to be used for diagnostic purposes. If you believe that you may be suffering from persistent depressive disorder, we encourage you to seek help from mental health professionals
We also made a video on the signs you're depressed, not lazy: https://youtu.be/q8HRGiUeZwc
Writer: Max Feng
Script Editor: Vanessa Tao
Script Manager: Kelly Soong
VO: Amanda Silvera (www.youtube.com/amandasilvera)
Animator: AwesomeKickArt (www.instagram.com/awesomekickart)
YouTube Manager: Cindy Cheong
References:
Mayo Clinic Staff. (2018, December 8). Persistent depressive disorder (dysthymia). Mayo Clinic.
Retrieved from www.mayoclinic.org/diseases-conditions/
persistent-depressive-disorder/symptoms-causes/syc-20350929
Stiehl, C. (2018, May 4). The Difference Between Depression and Persistent Depressive Disorder, aka
Dysthymia. SELF. Retrieved from www.self.com/story/persistent-depressive-disorder-depression
Familydoctor.org Editorial Staff. (2020, March 31). Persistent Depressive Disorder (PDD).
familydoctor.org. Retrieved from familydoctor.org/condition/persistent-depressive-disorder/
Devash, M. (2020, February 18). Let's Talk About Chronic Depression. HealthCentral. www.healthcentral.com/condition/chronic-depression
- published: 25 Aug 2022
- views: 167486
14:17
Learning to Live with Clinical Depression | Angelica Galluzzo | TEDxWesternU
Angelica shares how living with depression has impacted her life. Angelica Galluzzo is a mental health advocate, largely motivated by her own struggles with men...
Angelica shares how living with depression has impacted her life. Angelica Galluzzo is a mental health advocate, largely motivated by her own struggles with mental illness. After battling depression and suicidal ideation for many years, she became passionate about making an impact, using her voice to create positive change, and normalizing the struggles that many of us go through.
In 2021, she started her own podcast, called The Revolutionized Mind, with the goals of providing a safe space for people to share their stories, raising awareness about various mental illnesses, and learning how to embrace true authenticity.
Angelica graduated with an Honors Specialization in Psychology at Western University and has also completed her safeTALK, ASIST, and Mental Health First Aid certifications. She currently works full-time for Jack.org, a national charity that focuses on improving youth mental health and dismantling barriers such as stigma, access to resources, and more. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
https://wn.com/Learning_To_Live_With_Clinical_Depression_|_Angelica_Galluzzo_|_Tedxwesternu
Angelica shares how living with depression has impacted her life. Angelica Galluzzo is a mental health advocate, largely motivated by her own struggles with mental illness. After battling depression and suicidal ideation for many years, she became passionate about making an impact, using her voice to create positive change, and normalizing the struggles that many of us go through.
In 2021, she started her own podcast, called The Revolutionized Mind, with the goals of providing a safe space for people to share their stories, raising awareness about various mental illnesses, and learning how to embrace true authenticity.
Angelica graduated with an Honors Specialization in Psychology at Western University and has also completed her safeTALK, ASIST, and Mental Health First Aid certifications. She currently works full-time for Jack.org, a national charity that focuses on improving youth mental health and dismantling barriers such as stigma, access to resources, and more. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- published: 01 Mar 2023
- views: 153578
3:34
How Depression Affects The Brain - Yale Medicine Explains
For more information on mental health or #YaleMedicine, visit: https://www.yalemedicine.org/conditions/topics/mental-health.
For many people, depression turns ...
For more information on mental health or #YaleMedicine, visit: https://www.yalemedicine.org/conditions/topics/mental-health.
For many people, depression turns out to be one of the most disabling illnesses that we have in society. Despite the treatments that we have available, many people are not responding that well. It's a disorder that can be very disabling in society. It's also a disorder that has medical consequences. By understand the neurobiology of depression we hope to be able more to find the right treatment for the patient suffering from this disease. The current standard of care for the treatment of depression is based on what we call the monoamine deficiency hypothesis. Essentially, presuming that one of three neurotransmitters in the brain is deficient or underactive. But the reality is, there are more than 100 neurotransmitters in the brain. And billions of connections between neurons. So we know that that's a limited hypothesis. Neurotransmitters can be thought of as the chemical messengers within the brain, it's what helps one cell in the brain communicate with another, to pass that message along from one brain region to another. For decades, we thought that the primary pathology, the primary cause of depression was some abnormality in these neurotransmitters, specifically serotonin or norepinephrine. However, norepinephrine and serotonin did not seem to be able to account for this cause, or to cause the symptoms of depression in people who had major depression. Instead, the chemical messengers between the nerve cells in the higher centers of the brain, which include glutamate and GABA, were possibilities as alternative causes for the symptoms of depression. When you're exposed to severe and chronic stress like people experience when they have depression, you lose some of the connections between the nerve cells. The communication in these circuits becomes inefficient and noisy, we think that the loss of these synaptic connections contributes to the biology of depression. There are clear differences between a healthy brain and a depressed brain. And the exciting thing is, when you treat that depression effectively, the brain goes back to looking like a healthy brain, both at the cellular level and at a global scale. It's critical to understand the neurobiology of depression and how the brain plays a role in that for two main reasons. One, it helps us understand how the disease develops and progresses, and we can start to target treatments based on that. We are in a new era of psychiatry. This is a paradigm shift, away from a model of monoaminergic deficiency to a fuller understanding of the brain as a complex neurochemical organ. All of the research is driven by the imperative to alleviate human suffering. Depression is one of the most substantial contributors to human suffering. The opportunity to make even a tiny dent in that is an incredible opportunity.
https://wn.com/How_Depression_Affects_The_Brain_Yale_Medicine_Explains
For more information on mental health or #YaleMedicine, visit: https://www.yalemedicine.org/conditions/topics/mental-health.
For many people, depression turns out to be one of the most disabling illnesses that we have in society. Despite the treatments that we have available, many people are not responding that well. It's a disorder that can be very disabling in society. It's also a disorder that has medical consequences. By understand the neurobiology of depression we hope to be able more to find the right treatment for the patient suffering from this disease. The current standard of care for the treatment of depression is based on what we call the monoamine deficiency hypothesis. Essentially, presuming that one of three neurotransmitters in the brain is deficient or underactive. But the reality is, there are more than 100 neurotransmitters in the brain. And billions of connections between neurons. So we know that that's a limited hypothesis. Neurotransmitters can be thought of as the chemical messengers within the brain, it's what helps one cell in the brain communicate with another, to pass that message along from one brain region to another. For decades, we thought that the primary pathology, the primary cause of depression was some abnormality in these neurotransmitters, specifically serotonin or norepinephrine. However, norepinephrine and serotonin did not seem to be able to account for this cause, or to cause the symptoms of depression in people who had major depression. Instead, the chemical messengers between the nerve cells in the higher centers of the brain, which include glutamate and GABA, were possibilities as alternative causes for the symptoms of depression. When you're exposed to severe and chronic stress like people experience when they have depression, you lose some of the connections between the nerve cells. The communication in these circuits becomes inefficient and noisy, we think that the loss of these synaptic connections contributes to the biology of depression. There are clear differences between a healthy brain and a depressed brain. And the exciting thing is, when you treat that depression effectively, the brain goes back to looking like a healthy brain, both at the cellular level and at a global scale. It's critical to understand the neurobiology of depression and how the brain plays a role in that for two main reasons. One, it helps us understand how the disease develops and progresses, and we can start to target treatments based on that. We are in a new era of psychiatry. This is a paradigm shift, away from a model of monoaminergic deficiency to a fuller understanding of the brain as a complex neurochemical organ. All of the research is driven by the imperative to alleviate human suffering. Depression is one of the most substantial contributors to human suffering. The opportunity to make even a tiny dent in that is an incredible opportunity.
- published: 26 May 2021
- views: 1877449
8:22
How I overcame depression by just sitting around | Jonathan Schoenmaker | TEDxDelft
Jonathan Schoenmaker struggled with depression. With the best intentions, his friends and family would try to help by saying all the wrong things. In the end, J...
Jonathan Schoenmaker struggled with depression. With the best intentions, his friends and family would try to help by saying all the wrong things. In the end, Jonathan found the best way for him to experience happiness. As it turned out, what he needed most wasn't what everyone told him it would be. Jonathan Schoenmaker: a 20 year old Dutch physics student at the TU Delft and winner of the TEDx Delft Award. Jonathan’s talk is about his experience of suffering years of depression and the steps one can actually take to try and help people with this serious disease This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
https://wn.com/How_I_Overcame_Depression_By_Just_Sitting_Around_|_Jonathan_Schoenmaker_|_Tedxdelft
Jonathan Schoenmaker struggled with depression. With the best intentions, his friends and family would try to help by saying all the wrong things. In the end, Jonathan found the best way for him to experience happiness. As it turned out, what he needed most wasn't what everyone told him it would be. Jonathan Schoenmaker: a 20 year old Dutch physics student at the TU Delft and winner of the TEDx Delft Award. Jonathan’s talk is about his experience of suffering years of depression and the steps one can actually take to try and help people with this serious disease This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- published: 10 May 2018
- views: 773253
16:05
"I'm Fine" - Learning To Live With Depression | Jake Tyler | TEDxBrighton
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great out...
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of online followers as he goes and attracting the attention of both the BBC and the Royal Family. In this talk, Jake shares his insights into living with depression and how connecting to and opening up to a wide online community has affected his relationship with depression.
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of online followers as he goes and attracting the attention of both the BBC and the Royal Family. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
https://wn.com/I'm_Fine_Learning_To_Live_With_Depression_|_Jake_Tyler_|_Tedxbrighton
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of online followers as he goes and attracting the attention of both the BBC and the Royal Family. In this talk, Jake shares his insights into living with depression and how connecting to and opening up to a wide online community has affected his relationship with depression.
Jake is 31 and lives with Depression. Last year Jake embarked on a journey to manage his mental health in a new way, through exercise, sharing and the great outdoors. Jake has now walked over 2000 miles around the UK, vlogging his experiences with thousands of online followers as he goes and attracting the attention of both the BBC and the Royal Family. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- published: 13 Feb 2018
- views: 4555169
10:52
Jordan Peterson's Advice For People With Depression
12 Rules for Life: An Antidote to Chaos: https://amzn.to/39phlNc
Beyond Order: 12 More Rules for Life: https://amzn.to/3dgVHfl
Jordan Peterson shares his advic...
12 Rules for Life: An Antidote to Chaos: https://amzn.to/39phlNc
Beyond Order: 12 More Rules for Life: https://amzn.to/3dgVHfl
Jordan Peterson shares his advice for people with depression. Watch this fantastic video until the end, you won't be disappointed. If you enjoyed, please be sure to like, subscribe, and share the video! 😀
Speaker: Jordan Peterson
Special Thanks To Jordan Peterson for allowing us to share!
YouTube: https:https://www.youtube.com/user/JordanPetersonVideos
Twitter: https://twitter.com/jordanbpeterson
Donate to support him:
Donation Link: https://www.jordanbpeterson.com/donate/
-----------------------------------------------------------------------
►Follow Motivation Ark:
Subscribe for new Motivational Videos every week: https://www.youtube.com/channel/UC9vLdyHatOhRrCwQXq3HmQQ
Follow us on:
Facebook: https://www.facebook.com/motivationark
Twitter:
Instagram:
Footage commercially licensed through Videoblocks and Artgrid.
►►Music:
Borrtex
Bandcamp: https://borrtex.bandcamp.com/
Soundcloud: https://soundcloud.com/user-910809074
Instagram: https://www.instagram.com/borrtex/
Youtube: https://www.youtube.com/Borrtex
https://wn.com/Jordan_Peterson's_Advice_For_People_With_Depression
12 Rules for Life: An Antidote to Chaos: https://amzn.to/39phlNc
Beyond Order: 12 More Rules for Life: https://amzn.to/3dgVHfl
Jordan Peterson shares his advice for people with depression. Watch this fantastic video until the end, you won't be disappointed. If you enjoyed, please be sure to like, subscribe, and share the video! 😀
Speaker: Jordan Peterson
Special Thanks To Jordan Peterson for allowing us to share!
YouTube: https:https://www.youtube.com/user/JordanPetersonVideos
Twitter: https://twitter.com/jordanbpeterson
Donate to support him:
Donation Link: https://www.jordanbpeterson.com/donate/
-----------------------------------------------------------------------
►Follow Motivation Ark:
Subscribe for new Motivational Videos every week: https://www.youtube.com/channel/UC9vLdyHatOhRrCwQXq3HmQQ
Follow us on:
Facebook: https://www.facebook.com/motivationark
Twitter:
Instagram:
Footage commercially licensed through Videoblocks and Artgrid.
►►Music:
Borrtex
Bandcamp: https://borrtex.bandcamp.com/
Soundcloud: https://soundcloud.com/user-910809074
Instagram: https://www.instagram.com/borrtex/
Youtube: https://www.youtube.com/Borrtex
- published: 01 Mar 2021
- views: 1767566
5:28
The Road to Healing: How Long Will Depression Recovery Take?
In this video, we're answering the question: "How long will depression recovery take?"
We're talking about the journey of healing from depression, and the vari...
In this video, we're answering the question: "How long will depression recovery take?"
We're talking about the journey of healing from depression, and the various factors that can influence how long the process will take.
We hope that this video is helpful as you embark on your own road to healing from depression. Thanks for watching!
#depression #cure
https://wn.com/The_Road_To_Healing_How_Long_Will_Depression_Recovery_Take
In this video, we're answering the question: "How long will depression recovery take?"
We're talking about the journey of healing from depression, and the various factors that can influence how long the process will take.
We hope that this video is helpful as you embark on your own road to healing from depression. Thanks for watching!
#depression #cure
- published: 17 Jul 2023
- views: 2694
2:02:03
Understanding & Conquering Depression
This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed c...
This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical systems that are altered in depression: norepinephrine, serotonin and dopamine. I discuss genetic predispositions to depression and how stress, thyroid hormone and cortisol play a role in many forms of depression. I also discuss inflammation as a common feature of many depression symptoms. I review 8 specific science-supported protocols for treating and avoiding depression, including EPA fatty acids (which have been shown to rival certain prescription treatments), how exercise protects against depression, studies of creatine, adjusting dopamine balance and more. I also discuss the results of ongoing clinical trials for ketamine and psilocybin for depression, how these compounds work and finally, I review how ketogenic diets can help in certain cases of depression, especially treatment-resistant major depression.
For an updated list of our current sponsors, please visit our website as previous sponsors mentioned in this podcast episode may no longer be affiliated with us: https://www.hubermanlab.com/sponsors
Social & Website
Instagram: https://www.instagram.com/hubermanlab
Threads: https://www.threads.net/@hubermanlab
Twitter: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
Website: https://www.hubermanlab.com
Newsletter: https://www.hubermanlab.com/newsletter
Apple Podcasts: https://apple.co/3thCToZ
Spotify: https://spoti.fi/3PYzuFs
Links
Review of EPAs for the Treatment of Depression - https://bit.ly/2Wl15ti
Review of Creatine for the Treatment of Depression - https://www.mdpi.com/520864
Recent Study on the Clinical Use of Psilocybin for Treatment of Depression - https://bit.ly/3sFSGMM
Timestamps
00:00:00 Mood Disorders & Maintaining Mental Health (Protocol 1)
00:07:10 Sponsors
00:11:15 Major Depression
00:18:40 “Anti-Self” Confabulation
00:21:42 Autonomic (Vegetative) Symptoms of Depression
00:26:58 Norepinephrine, Dopamine & Serotonin
00:31:50 SSRIs (Prozac, Zoloft, etc.): Selective Serotonin Reuptake Inhibitors
00:37:00 Epinephrine/Motor Functions, Dopamine/Motivation & Craving, Serotonin/Emotions
00:39:33 Physical & Emotional Pain are Linked: Substance P
00:41:50 Hormones & Depression: Thyroid & Cortisol
00:46:50 Genetic Susceptibility to Depression: Impact of Stress
00:50:50 Understanding Biological Mechanism Is Key: Recipes versus Skills
00:52:50 Tools for Dealing with Depression: Logic & Implementation (Protocol 2)
00:56:25 Brain Inflammation & Mental State: Cytokines, Prostaglandins, etc.
00:59:20 Protocol 3: Essential Fatty Acids (Omega-3, EPAs: Eicosapentaenoic Acid)*
01:02:50 How EPAs Help Offset Depression: Serotonin Synthesis, Kynurenine, Quinolinic Acid
01:05:25 Protocol 4: How Exercise Offsets Depression
01:11:44 Protocol 5: Creatine Monohydrate, Forebrain Function & NMDA receptors*
01:20:30 Protocol 6*: Ketamine, PCP (*Prescription-Only), & NMDA-Receptor Function
01:33:08 Protocol 7*: Psychedelics (*In Clinical Trials) for Major Depression: Psilocybin*
01:47:00 Protocol 8: Ketogenic Diet, GABA (Gamma-Aminobutyric Acid)
01:54:50 Summary of Protocols Covered
02:00:10 Support & Additional Resources
#Depression #HubermanLab #Dopamine
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Disclaimer: https://www.hubermanlab.com/disclaimer
https://wn.com/Understanding_Conquering_Depression
This episode, I explain what major depression is at the biological and psychological level and the various treatments that peer-reviewed studies have revealed can help prevent and treat depression. I explain the three major chemical systems that are altered in depression: norepinephrine, serotonin and dopamine. I discuss genetic predispositions to depression and how stress, thyroid hormone and cortisol play a role in many forms of depression. I also discuss inflammation as a common feature of many depression symptoms. I review 8 specific science-supported protocols for treating and avoiding depression, including EPA fatty acids (which have been shown to rival certain prescription treatments), how exercise protects against depression, studies of creatine, adjusting dopamine balance and more. I also discuss the results of ongoing clinical trials for ketamine and psilocybin for depression, how these compounds work and finally, I review how ketogenic diets can help in certain cases of depression, especially treatment-resistant major depression.
For an updated list of our current sponsors, please visit our website as previous sponsors mentioned in this podcast episode may no longer be affiliated with us: https://www.hubermanlab.com/sponsors
Social & Website
Instagram: https://www.instagram.com/hubermanlab
Threads: https://www.threads.net/@hubermanlab
Twitter: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
Website: https://www.hubermanlab.com
Newsletter: https://www.hubermanlab.com/newsletter
Apple Podcasts: https://apple.co/3thCToZ
Spotify: https://spoti.fi/3PYzuFs
Links
Review of EPAs for the Treatment of Depression - https://bit.ly/2Wl15ti
Review of Creatine for the Treatment of Depression - https://www.mdpi.com/520864
Recent Study on the Clinical Use of Psilocybin for Treatment of Depression - https://bit.ly/3sFSGMM
Timestamps
00:00:00 Mood Disorders & Maintaining Mental Health (Protocol 1)
00:07:10 Sponsors
00:11:15 Major Depression
00:18:40 “Anti-Self” Confabulation
00:21:42 Autonomic (Vegetative) Symptoms of Depression
00:26:58 Norepinephrine, Dopamine & Serotonin
00:31:50 SSRIs (Prozac, Zoloft, etc.): Selective Serotonin Reuptake Inhibitors
00:37:00 Epinephrine/Motor Functions, Dopamine/Motivation & Craving, Serotonin/Emotions
00:39:33 Physical & Emotional Pain are Linked: Substance P
00:41:50 Hormones & Depression: Thyroid & Cortisol
00:46:50 Genetic Susceptibility to Depression: Impact of Stress
00:50:50 Understanding Biological Mechanism Is Key: Recipes versus Skills
00:52:50 Tools for Dealing with Depression: Logic & Implementation (Protocol 2)
00:56:25 Brain Inflammation & Mental State: Cytokines, Prostaglandins, etc.
00:59:20 Protocol 3: Essential Fatty Acids (Omega-3, EPAs: Eicosapentaenoic Acid)*
01:02:50 How EPAs Help Offset Depression: Serotonin Synthesis, Kynurenine, Quinolinic Acid
01:05:25 Protocol 4: How Exercise Offsets Depression
01:11:44 Protocol 5: Creatine Monohydrate, Forebrain Function & NMDA receptors*
01:20:30 Protocol 6*: Ketamine, PCP (*Prescription-Only), & NMDA-Receptor Function
01:33:08 Protocol 7*: Psychedelics (*In Clinical Trials) for Major Depression: Psilocybin*
01:47:00 Protocol 8: Ketogenic Diet, GABA (Gamma-Aminobutyric Acid)
01:54:50 Summary of Protocols Covered
02:00:10 Support & Additional Resources
#Depression #HubermanLab #Dopamine
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Disclaimer: https://www.hubermanlab.com/disclaimer
- published: 23 Aug 2021
- views: 1888173
8:44
My Experience With Depression & How I Overcome It
Have you experience depression? What was your story? Are you looking for how to overcome depression?
VOICE: Amanda Silvera
Animator: Rina C.
YouTube Manager...
Have you experience depression? What was your story? Are you looking for how to overcome depression?
VOICE: Amanda Silvera
Animator: Rina C.
YouTube Manager: Cindy Cheong
Have a story you would like to share? Email us at
[email protected] with your stories.
#bedtimestories #depression
https://wn.com/My_Experience_With_Depression_How_I_Overcome_It
Have you experience depression? What was your story? Are you looking for how to overcome depression?
VOICE: Amanda Silvera
Animator: Rina C.
YouTube Manager: Cindy Cheong
Have a story you would like to share? Email us at
[email protected] with your stories.
#bedtimestories #depression
- published: 05 Sep 2021
- views: 361995