-
THE AMAZING DIGITAL CIRCUS - Ep 2: Candy Carrier Chaos!
The gang are BACK for a WAaAaAaACKY candy filled adventure! They also discover that their lives literally have no meaning. Woohoo! So waaccky!!!!!
ALSOOO we just dropped the entire main Digital Circus characters as PLUSHIES!!!: https://digitalcircus.store/ Consider getting one to help support the production of more episodes. No pressure though! Have a great day ❤️
published: 03 May 2024
-
Sick Song | CoComelon Nursery Rhymes & Kids Songs
Being sick is no fun, but Mommy and Daddy can help JJ feel better!
https://www.youtube.com/c/Cocomelon?sub_confirmation=1
Lyrics:
My little baby, not feeling well?
You have a fever, Mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
Your nose is running, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
I hear you coughing, mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby not feeling well?
You have a cold, oh, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
About Cocomelon:
Where kids can be happy and smart!
At Cocomelon...
published: 20 Jul 2018
-
DRAGON BALL LEGENDS "LL Super Saiyan God SS Goku & Vegeta", "SP Broly: Fury" Trailer
\It's DRAGON BALL LEGENDS' 6th anniversary!/
Featured character, "Super Saiyan God SS Goku & Vegeta," joins the fray as a LEGENDS LIMITED Tag Character!
Super Saiyan God SS Goku & Vegeta has a Synchro Gauge, and when it's full, this character can fuse into Super Saiyan God SS Gogeta!
Plus, Broly: Fury joins the fight in SPARKING rarity!
The fierce battle scenes from the "DRAGON BALL Super: Broly" movie recreated here in LEGENDS are a must-see!
Don't miss your chance to get these amazing characters!
●Summon Period: 5/25/2024 – 7/17/2024 06:00 (UTC) (Sched.)
*Summon period and contents subject to change without notice.
ーーーーーーーーーー
Visit our website: https://dble.bn-ent.net/en/
X: https://twitter.com/db_legends
Facebook: https://www.facebook.com/DBLegends.Official
Instagram: https://www.i...
published: 25 May 2024
-
Looks like I’ll need to buy more cookies!
published: 15 Oct 2023
-
i'm lactose intolerant
#lactosefree
published: 12 Dec 2022
-
Auli'i Cravalho - How Far I'll Go (from Moana/Official Video)
Disney's Moana is now streaming on Disney+.
Disney+ is the ultimate streaming destination for entertainment from Disney, Pixar, Marvel, Star Wars, and National Geographic. Access it all at https://www.disneyplus.com/
Subscribe to DisneyMusicVEVO 🔔 for all the latest Disney music videos: https://www.youtube.com/@DisneyMusicVEVO?sub_confirmation=1
▶️ Watch all Moana music videos featuring "How Far I'll Go," "You're Welcome," "Shiny" and more here: https://www.youtube.com/playlist?list=PLiNVoBckLqLnpvY0btY40oI5k9c0Tqa0I
✨ Also check out the Disney Hits playlist : https://www.youtube.com/watch?v=79DijItQXMM&list=PLiNVoBckLqLmdcbotc6n_MjdTDCHLiYDo
🎤 Disney Sing-Alongs playlist: https://www.youtube.com/playlist?list=PLiNVoBckLqLlwlfLIh3a4bmuqzLkgEjjt
Connect with Disney Music:
Instagram: h...
published: 12 Dec 2016
-
Betty's Nursery 2 | ROBLOX | ANG TEACHER NG MGA KALOKOHAN!
Like, Comment and Subscribe for more videos like this!
Follow me on my facebook page:
https://www.facebook.com/itsTaleOfEL
Follow me on Roblox:
PlayofEL
#RobloxTagalog
#Playofel
#BarrysPrison
published: 16 Apr 2024
-
one day i’ll learn #funny
published: 24 May 2024
-
If You Build It, I'll Pay For It!
If you build it out of Lego, I will pay for it! Let's see who wins!
I Bought CHEAP Temu Products To See If They Work...
► Today we are testing Temu Gadgets to see if they are worth spending money on!
Best Pancake Art Wins $1,000!
► https://youtu.be/omUja7lzKDs
★ Follow me on social media @Jesser ★
● Instagram https://instagram.com/jesser
● Twitter https://twitter.com/jesser
★ BUCKETSQUAD APPAREL ★
► https://bucketsquad.com/
published: 24 May 2024
-
Sharks in the Water 2: Rise of the Shark King! 🦈 Floor is Lava Game | Danny Go! Songs for Kids
Are you ready to DIVE into a thrilling underwater adventure? 🌊 Swim along with Danny as you navigate shark-infested waters in search of the legendary Giant Golden Shark Tooth! Along the way, you’ll encounter fascinating sea creatures, swim through dangerous coral, and collect precious gems. 🦑🪸💎 Oh, but if you see a SHARK, you better get out of the water and up on something safe! 🦈
Wanna keep dancing? Here's some of our other favorite Danny Go dance songs!
Sharks in the Water! - https://youtu.be/LX-phYsiMdg
The Floor is Lava Dance - https://youtu.be/nEUTY8n2iZo
The Cowboy Dance - https://youtu.be/D52H25i1KxI
The Color Dance - https://youtu.be/q-6g_viAcIk
The Ice King Freeze Dance - https://youtu.be/c9YiakkdS8k
The Wiggle Dance Song - https://youtu.be/DsUPVERZFlI
The Fire & Ice Freeze Danc...
published: 22 Apr 2024
25:14
THE AMAZING DIGITAL CIRCUS - Ep 2: Candy Carrier Chaos!
The gang are BACK for a WAaAaAaACKY candy filled adventure! They also discover that their lives literally have no meaning. Woohoo! So waaccky!!!!!
ALSOOO we j...
The gang are BACK for a WAaAaAaACKY candy filled adventure! They also discover that their lives literally have no meaning. Woohoo! So waaccky!!!!!
ALSOOO we just dropped the entire main Digital Circus characters as PLUSHIES!!!: https://digitalcircus.store/ Consider getting one to help support the production of more episodes. No pressure though! Have a great day ❤️
https://wn.com/The_Amazing_Digital_Circus_Ep_2_Candy_Carrier_Chaos
The gang are BACK for a WAaAaAaACKY candy filled adventure! They also discover that their lives literally have no meaning. Woohoo! So waaccky!!!!!
ALSOOO we just dropped the entire main Digital Circus characters as PLUSHIES!!!: https://digitalcircus.store/ Consider getting one to help support the production of more episodes. No pressure though! Have a great day ❤️
- published: 03 May 2024
- views: 135276947
2:35
Sick Song | CoComelon Nursery Rhymes & Kids Songs
Being sick is no fun, but Mommy and Daddy can help JJ feel better!
https://www.youtube.com/c/Cocomelon?sub_confirmation=1
Lyrics:
My little baby, not feeling...
Being sick is no fun, but Mommy and Daddy can help JJ feel better!
https://www.youtube.com/c/Cocomelon?sub_confirmation=1
Lyrics:
My little baby, not feeling well?
You have a fever, Mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
Your nose is running, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
I hear you coughing, mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby not feeling well?
You have a cold, oh, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
About Cocomelon:
Where kids can be happy and smart!
At Cocomelon, our goal is to help make learning a fun and enjoyable experience for kids by creating beautiful 3D animation, educational lyrics, and toe-tapping music.
Kids will laugh, dance, sing, and play along with our videos, learning letters, numbers, animal sounds, colors, and much, much more while simply enjoying our friendly characters and fun stories.
We also make life easier for parents who want to keep their kids happily entertained, giving you the peace of mind that your children are receiving quality educational content. Our videos also give you an opportunity to teach and play with your children as you both watch!
WEBSITE: http://www.Cocomelon.com
FACEBOOK: https://www.facebook.com/Cocomelonkids
INSTAGRAM: https://www.instagram.com/cocomelon_official/
TWITTER: https://www.twitter.com/Cocomelonkids
Copyright © Treasure Studio, Inc. All rights reserved.
https://wn.com/Sick_Song_|_Cocomelon_Nursery_Rhymes_Kids_Songs
Being sick is no fun, but Mommy and Daddy can help JJ feel better!
https://www.youtube.com/c/Cocomelon?sub_confirmation=1
Lyrics:
My little baby, not feeling well?
You have a fever, Mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
Your nose is running, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby, not feeling well?
I hear you coughing, mommy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
My little baby not feeling well?
You have a cold, oh, Daddy can tell
Rest little baby, I’ll care for you
You’ll get well soon, I’ll make sure you do
About Cocomelon:
Where kids can be happy and smart!
At Cocomelon, our goal is to help make learning a fun and enjoyable experience for kids by creating beautiful 3D animation, educational lyrics, and toe-tapping music.
Kids will laugh, dance, sing, and play along with our videos, learning letters, numbers, animal sounds, colors, and much, much more while simply enjoying our friendly characters and fun stories.
We also make life easier for parents who want to keep their kids happily entertained, giving you the peace of mind that your children are receiving quality educational content. Our videos also give you an opportunity to teach and play with your children as you both watch!
WEBSITE: http://www.Cocomelon.com
FACEBOOK: https://www.facebook.com/Cocomelonkids
INSTAGRAM: https://www.instagram.com/cocomelon_official/
TWITTER: https://www.twitter.com/Cocomelonkids
Copyright © Treasure Studio, Inc. All rights reserved.
- published: 20 Jul 2018
- views: 2052712505
2:47
DRAGON BALL LEGENDS "LL Super Saiyan God SS Goku & Vegeta", "SP Broly: Fury" Trailer
\It's DRAGON BALL LEGENDS' 6th anniversary!/
Featured character, "Super Saiyan God SS Goku & Vegeta," joins the fray as a LEGENDS LIMITED Tag Character!
Super ...
\It's DRAGON BALL LEGENDS' 6th anniversary!/
Featured character, "Super Saiyan God SS Goku & Vegeta," joins the fray as a LEGENDS LIMITED Tag Character!
Super Saiyan God SS Goku & Vegeta has a Synchro Gauge, and when it's full, this character can fuse into Super Saiyan God SS Gogeta!
Plus, Broly: Fury joins the fight in SPARKING rarity!
The fierce battle scenes from the "DRAGON BALL Super: Broly" movie recreated here in LEGENDS are a must-see!
Don't miss your chance to get these amazing characters!
●Summon Period: 5/25/2024 – 7/17/2024 06:00 (UTC) (Sched.)
*Summon period and contents subject to change without notice.
ーーーーーーーーーー
Visit our website: https://dble.bn-ent.net/en/
X: https://twitter.com/db_legends
Facebook: https://www.facebook.com/DBLegends.Official
Instagram: https://www.instagram.com/db_legends/
Download Now: https://bnent.jp/dbl_yt_des/
ーーーーーーーーーー
(c)BIRD STUDIO/SHUEISHA, TOEI ANIMATION (c)Bandai Namco Entertainment Inc.
https://wn.com/Dragon_Ball_Legends_Ll_Super_Saiyan_God_Ss_Goku_Vegeta_,_Sp_Broly_Fury_Trailer
\It's DRAGON BALL LEGENDS' 6th anniversary!/
Featured character, "Super Saiyan God SS Goku & Vegeta," joins the fray as a LEGENDS LIMITED Tag Character!
Super Saiyan God SS Goku & Vegeta has a Synchro Gauge, and when it's full, this character can fuse into Super Saiyan God SS Gogeta!
Plus, Broly: Fury joins the fight in SPARKING rarity!
The fierce battle scenes from the "DRAGON BALL Super: Broly" movie recreated here in LEGENDS are a must-see!
Don't miss your chance to get these amazing characters!
●Summon Period: 5/25/2024 – 7/17/2024 06:00 (UTC) (Sched.)
*Summon period and contents subject to change without notice.
ーーーーーーーーーー
Visit our website: https://dble.bn-ent.net/en/
X: https://twitter.com/db_legends
Facebook: https://www.facebook.com/DBLegends.Official
Instagram: https://www.instagram.com/db_legends/
Download Now: https://bnent.jp/dbl_yt_des/
ーーーーーーーーーー
(c)BIRD STUDIO/SHUEISHA, TOEI ANIMATION (c)Bandai Namco Entertainment Inc.
- published: 25 May 2024
- views: 20216
2:36
Auli'i Cravalho - How Far I'll Go (from Moana/Official Video)
Disney's Moana is now streaming on Disney+.
Disney+ is the ultimate streaming destination for entertainment from Disney, Pixar, Marvel, Star Wars, and National...
Disney's Moana is now streaming on Disney+.
Disney+ is the ultimate streaming destination for entertainment from Disney, Pixar, Marvel, Star Wars, and National Geographic. Access it all at https://www.disneyplus.com/
Subscribe to DisneyMusicVEVO 🔔 for all the latest Disney music videos: https://www.youtube.com/@DisneyMusicVEVO?sub_confirmation=1
▶️ Watch all Moana music videos featuring "How Far I'll Go," "You're Welcome," "Shiny" and more here: https://www.youtube.com/playlist?list=PLiNVoBckLqLnpvY0btY40oI5k9c0Tqa0I
✨ Also check out the Disney Hits playlist : https://www.youtube.com/watch?v=79DijItQXMM&list=PLiNVoBckLqLmdcbotc6n_MjdTDCHLiYDo
🎤 Disney Sing-Alongs playlist: https://www.youtube.com/playlist?list=PLiNVoBckLqLlwlfLIh3a4bmuqzLkgEjjt
Connect with Disney Music:
Instagram: https://instagram.com/disneymusic
Facebook: https://facebook.com/disneymusic
Twitter: https://twitter.com/disneymusic
TikTok: https://tiktok.com/@disneymusic
🌊🌊🌊
About Moana:
For centuries, the greatest sailors in the world masterfully navigated the vast Pacific, discovering the many islands of Oceania. But then, 3,000 years ago, their voyages stopped for a millennium – and no one knows exactly why. From Walt Disney Animation Studios comes “Moana,” a sweeping, CG-animated feature film about an adventurous teenager who is inspired to leave the safety and security of her island on a daring journey to save her people. Inexplicably drawn to the ocean, Moana (voice of Auliʻi Cravalho) convinces the mighty demigod Maui (voice of Dwayne Johnson) to join her mission, and he reluctantly helps her become a wayfinder like her ancestors who sailed before her. Together, they voyage across the open ocean on an action-packed adventure, encountering enormous monsters and impossible odds, and along the way, Moana fulfills her quest and discovers the one thing she’s always sought: her own identity. Directed by the renowned filmmaking team of Ron Clements and John Musker (“The Little Mermaid,” “Aladdin,” “The Princess & the Frog”), produced by Osnat Shurer (“Lifted,” “One Man Band”), and featuring music by Lin-Manuel Miranda, Mark Mancina and Opetaia Foa‘i, “Moana” is sailing on Disney+ now.
#DisneyMoana #HowFarIllGo #AuliiCravalho
"How Far I'll Go" from Disney's Moana
Performed by: Auliʻi Cravalho
Music video by Auli'i Cravalho performing How Far I'll Go. (C) 2016 Walt Disney Records
https://wn.com/Auli'i_Cravalho_How_Far_I'll_Go_(From_Moana_Official_Video)
Disney's Moana is now streaming on Disney+.
Disney+ is the ultimate streaming destination for entertainment from Disney, Pixar, Marvel, Star Wars, and National Geographic. Access it all at https://www.disneyplus.com/
Subscribe to DisneyMusicVEVO 🔔 for all the latest Disney music videos: https://www.youtube.com/@DisneyMusicVEVO?sub_confirmation=1
▶️ Watch all Moana music videos featuring "How Far I'll Go," "You're Welcome," "Shiny" and more here: https://www.youtube.com/playlist?list=PLiNVoBckLqLnpvY0btY40oI5k9c0Tqa0I
✨ Also check out the Disney Hits playlist : https://www.youtube.com/watch?v=79DijItQXMM&list=PLiNVoBckLqLmdcbotc6n_MjdTDCHLiYDo
🎤 Disney Sing-Alongs playlist: https://www.youtube.com/playlist?list=PLiNVoBckLqLlwlfLIh3a4bmuqzLkgEjjt
Connect with Disney Music:
Instagram: https://instagram.com/disneymusic
Facebook: https://facebook.com/disneymusic
Twitter: https://twitter.com/disneymusic
TikTok: https://tiktok.com/@disneymusic
🌊🌊🌊
About Moana:
For centuries, the greatest sailors in the world masterfully navigated the vast Pacific, discovering the many islands of Oceania. But then, 3,000 years ago, their voyages stopped for a millennium – and no one knows exactly why. From Walt Disney Animation Studios comes “Moana,” a sweeping, CG-animated feature film about an adventurous teenager who is inspired to leave the safety and security of her island on a daring journey to save her people. Inexplicably drawn to the ocean, Moana (voice of Auliʻi Cravalho) convinces the mighty demigod Maui (voice of Dwayne Johnson) to join her mission, and he reluctantly helps her become a wayfinder like her ancestors who sailed before her. Together, they voyage across the open ocean on an action-packed adventure, encountering enormous monsters and impossible odds, and along the way, Moana fulfills her quest and discovers the one thing she’s always sought: her own identity. Directed by the renowned filmmaking team of Ron Clements and John Musker (“The Little Mermaid,” “Aladdin,” “The Princess & the Frog”), produced by Osnat Shurer (“Lifted,” “One Man Band”), and featuring music by Lin-Manuel Miranda, Mark Mancina and Opetaia Foa‘i, “Moana” is sailing on Disney+ now.
#DisneyMoana #HowFarIllGo #AuliiCravalho
"How Far I'll Go" from Disney's Moana
Performed by: Auliʻi Cravalho
Music video by Auli'i Cravalho performing How Far I'll Go. (C) 2016 Walt Disney Records
- published: 12 Dec 2016
- views: 1374770968
10:20
Betty's Nursery 2 | ROBLOX | ANG TEACHER NG MGA KALOKOHAN!
Like, Comment and Subscribe for more videos like this!
Follow me on my facebook page:
https://www.facebook.com/itsTaleOfEL
Follow me on Roblox:
PlayofEL
#Rob...
Like, Comment and Subscribe for more videos like this!
Follow me on my facebook page:
https://www.facebook.com/itsTaleOfEL
Follow me on Roblox:
PlayofEL
#RobloxTagalog
#Playofel
#BarrysPrison
https://wn.com/Betty's_Nursery_2_|_Roblox_|_Ang_Teacher_Ng_Mga_Kalokohan
Like, Comment and Subscribe for more videos like this!
Follow me on my facebook page:
https://www.facebook.com/itsTaleOfEL
Follow me on Roblox:
PlayofEL
#RobloxTagalog
#Playofel
#BarrysPrison
- published: 16 Apr 2024
- views: 697273
30:26
If You Build It, I'll Pay For It!
If you build it out of Lego, I will pay for it! Let's see who wins!
I Bought CHEAP Temu Products To See If They Work...
► Today we are testing Temu Gadgets to ...
If you build it out of Lego, I will pay for it! Let's see who wins!
I Bought CHEAP Temu Products To See If They Work...
► Today we are testing Temu Gadgets to see if they are worth spending money on!
Best Pancake Art Wins $1,000!
► https://youtu.be/omUja7lzKDs
★ Follow me on social media @Jesser ★
● Instagram https://instagram.com/jesser
● Twitter https://twitter.com/jesser
★ BUCKETSQUAD APPAREL ★
► https://bucketsquad.com/
https://wn.com/If_You_Build_It,_I'll_Pay_For_It
If you build it out of Lego, I will pay for it! Let's see who wins!
I Bought CHEAP Temu Products To See If They Work...
► Today we are testing Temu Gadgets to see if they are worth spending money on!
Best Pancake Art Wins $1,000!
► https://youtu.be/omUja7lzKDs
★ Follow me on social media @Jesser ★
● Instagram https://instagram.com/jesser
● Twitter https://twitter.com/jesser
★ BUCKETSQUAD APPAREL ★
► https://bucketsquad.com/
- published: 24 May 2024
- views: 138714
4:22
Sharks in the Water 2: Rise of the Shark King! 🦈 Floor is Lava Game | Danny Go! Songs for Kids
Are you ready to DIVE into a thrilling underwater adventure? 🌊 Swim along with Danny as you navigate shark-infested waters in search of the legendary Giant Gold...
Are you ready to DIVE into a thrilling underwater adventure? 🌊 Swim along with Danny as you navigate shark-infested waters in search of the legendary Giant Golden Shark Tooth! Along the way, you’ll encounter fascinating sea creatures, swim through dangerous coral, and collect precious gems. 🦑🪸💎 Oh, but if you see a SHARK, you better get out of the water and up on something safe! 🦈
Wanna keep dancing? Here's some of our other favorite Danny Go dance songs!
Sharks in the Water! - https://youtu.be/LX-phYsiMdg
The Floor is Lava Dance - https://youtu.be/nEUTY8n2iZo
The Cowboy Dance - https://youtu.be/D52H25i1KxI
The Color Dance - https://youtu.be/q-6g_viAcIk
The Ice King Freeze Dance - https://youtu.be/c9YiakkdS8k
The Wiggle Dance Song - https://youtu.be/DsUPVERZFlI
The Fire & Ice Freeze Dance - https://youtu.be/XYEjLXxT2xg
The Robot Dance - https://youtu.be/T8Df3VZCKUc
The Monkey Dance - https://youtu.be/qQB-V4r-uMY
The Stomp Clap Dance Song - https://youtu.be/nvDLe3FHcuY
The Dinosaur Dance - https://youtu.be/qSkVgH-4PKw
For free downloads and other goodies, visit dannygo.net!
Get your kids moving, having fun, being silly and learning with Danny Go! Tired of YouTube simple nursery rhymes? Every Danny Go! video is packed with original songs for kids and dances for kids that even mom, dad, teachers and caretakers can enjoy! Play freeze games, floor is lava games, this or that games, construction vehicle games and more! Dance along with us to songs about cowboys, dinosaurs, monkeys, robots, unicorns, cartoons, diggers, space, cars, and more! When we're not moving and grooving, we will be taking exciting field trips to fire stations, trampoline parks, animal shelters, going on treasure hunts and more. We will see you there!
Danny Go! on Instagram: https://www.instagram.com/dannygo_official/
Danny Go! on Facebook: https://www.facebook.com/dannygoofficial
Danny Go! on Cameo: https://www.cameo.com/dannygo
Stream Danny Go! music:
Spotify - https://open.spotify.com/artist/3DQZdH2A5YhL1XIt4DKfUm
Apple Music - https://music.apple.com/us/artist/danny-go/1475674203
Amazon Music - https://music.amazon.com/artists/B07W7ML8Q4/danny-go
© 2024 Danny Go, LLC. All Rights Reserved.
https://wn.com/Sharks_In_The_Water_2_Rise_Of_The_Shark_King_🦈_Floor_Is_Lava_Game_|_Danny_Go_Songs_For_Kids
Are you ready to DIVE into a thrilling underwater adventure? 🌊 Swim along with Danny as you navigate shark-infested waters in search of the legendary Giant Golden Shark Tooth! Along the way, you’ll encounter fascinating sea creatures, swim through dangerous coral, and collect precious gems. 🦑🪸💎 Oh, but if you see a SHARK, you better get out of the water and up on something safe! 🦈
Wanna keep dancing? Here's some of our other favorite Danny Go dance songs!
Sharks in the Water! - https://youtu.be/LX-phYsiMdg
The Floor is Lava Dance - https://youtu.be/nEUTY8n2iZo
The Cowboy Dance - https://youtu.be/D52H25i1KxI
The Color Dance - https://youtu.be/q-6g_viAcIk
The Ice King Freeze Dance - https://youtu.be/c9YiakkdS8k
The Wiggle Dance Song - https://youtu.be/DsUPVERZFlI
The Fire & Ice Freeze Dance - https://youtu.be/XYEjLXxT2xg
The Robot Dance - https://youtu.be/T8Df3VZCKUc
The Monkey Dance - https://youtu.be/qQB-V4r-uMY
The Stomp Clap Dance Song - https://youtu.be/nvDLe3FHcuY
The Dinosaur Dance - https://youtu.be/qSkVgH-4PKw
For free downloads and other goodies, visit dannygo.net!
Get your kids moving, having fun, being silly and learning with Danny Go! Tired of YouTube simple nursery rhymes? Every Danny Go! video is packed with original songs for kids and dances for kids that even mom, dad, teachers and caretakers can enjoy! Play freeze games, floor is lava games, this or that games, construction vehicle games and more! Dance along with us to songs about cowboys, dinosaurs, monkeys, robots, unicorns, cartoons, diggers, space, cars, and more! When we're not moving and grooving, we will be taking exciting field trips to fire stations, trampoline parks, animal shelters, going on treasure hunts and more. We will see you there!
Danny Go! on Instagram: https://www.instagram.com/dannygo_official/
Danny Go! on Facebook: https://www.facebook.com/dannygoofficial
Danny Go! on Cameo: https://www.cameo.com/dannygo
Stream Danny Go! music:
Spotify - https://open.spotify.com/artist/3DQZdH2A5YhL1XIt4DKfUm
Apple Music - https://music.apple.com/us/artist/danny-go/1475674203
Amazon Music - https://music.amazon.com/artists/B07W7ML8Q4/danny-go
© 2024 Danny Go, LLC. All Rights Reserved.
- published: 22 Apr 2024
- views: 76364965
-
#LL37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video 1
#LL37 #alarmin #psoriasis LL-37 has attracted increased attention due to its contribution to the development of inflammatory & autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis , psoriasis, atopic dermatitis & atherosclerosis. LL-37 is a proteolytic fragment of cathelicidin which works as a defensin by inserting into the membranes of bacterial pathogens, and as alarmin in stimulating chemotaxis of innate immune cells, & alters the structure & efficacy of various cytokines.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&li...
published: 16 Jan 2023
-
L2.12: Mechanism of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
#immunology #neutrophils #antimicrobial #mechanismofaction
This is the 12th video of chapter 2 of immunology and focuses on the secondary granules in Neutrophils and mechanisms of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
The links to the other 11 videos are the following
L2.1: Immunology; Hematopoiesis; Hematopoietic Stem Cell and Common Myeloid-Erythroid Progenitor
https://youtu.be/vpb_XN5o60k
L2.2: Immunology; Hematopoiesis; Hematopoietic Stem Cell (HSC) and Common Lymphoid Progenitor
https://youtu.be/O4l4s1QwwQ0
L2.3: Immunology; Granulocytes and Agranulocytes; A quick review
https://youtu.be/bvPw4QWu7zE
L2.4: Immunology; Neutrophils; The first line defender/Granulopoiesis/Geimsa stain
https://youtu.be/cwfRiE7JEj8
L2.5: Immunology; Neutrophils/ Gr...
published: 30 Mar 2024
-
What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
Hello Everyone
Today's video is : What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
If you like my 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video, please give it a big thumbs up.
If you found this 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video useful, please consider subscribing.
Also, if you'd like to see more videos like 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' leave me a comment below.
Topic: What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
Tags: Medical Videos, Medical Lectures, dental emergenc...
published: 02 Oct 2020
-
Generation and Structure of Human Cathelicidin LL37
#dermaimmunology #LL37 #Cathelicidin
LL-37 acts as an antimicrobial peptide & also as an immunomodulator, potentially CONTRIBUTING TO the onset of autoimmune diseases. LL-37 is the only Cathelicidin member in humans.
🔔Subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388365/
Key moments"
00:00 Introduction
02:35 LL37 Generation
11:35 LL37 Structure
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube....
published: 14 Nov 2023
-
#shorts LL-37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video #2
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
published: 18 Sep 2023
-
LL-37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video #2
#LL-37 has an affinity for phospholipid membranes. So, LL-37 contributes to the nuclear membrane disruption & the formation of #NETs. LL-37 in combination with DNA or RNA may contribute to a self-sustaining & amplifying vicious cycle of ongoing & progressive chronic #inflammation. LL-37 peptide-containing complexes, in which LL-37 protects NET-derived DNA from degradation accumulation of immunogenic NETs & induction of anti-NET antibodies.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
key moments:
00:00 Introduction
02:40 LL-37 in psoriasis
03:27 LL-37 in LE
05:49 LL-37 in other Autoimmune & Inflammatory ...
published: 20 Jan 2023
-
Cathelicidins: Vitamin D's antimicrobial arsenal
Today, I detail the antimicrobial proteins Cathelicidins, and how they are dependent on adequate vitamin D intake. I also show you how to enhance the function of any supplemental vitamin D you're taking.
ENZYMENTAL Episode 185
Motion graphics by http://www.canva.com
#enzymental #jasoncarter #stayhealthy
published: 25 Feb 2022
-
Joshua McClure - Antimicrobial Peptoids: Next Generation Anti-infectives
MaxWell Bioscience's mission is to prove our disruptive new "peptoid" anti-infectives destroy humanity's top threat - highly infectious pandemic microbes - like untreatable viruses, drug-resistant bacteria, and drug-resistant fungi. Maxwell's anti-infectives have been shown by multiple independent labs (including Stanford, NYU and others) to be rapid killers of the worst viruses, drug-resistant fungi and treatment-resistant bacteria. These labs show Maxwell peptoids are highly selective for pathogens over human cells, are biostable, effective at low doses, and rapidly destroy biofilm defenses. MaxWell Bioscience are in preclinical stage now, preparing for human trials.
https://maxwellbiosciences.com
Joshua McClure is Founder and CEO of MaxWell Biosciences. Joshua has co-invented and secu...
published: 22 Dec 2019
-
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. Biswajit Brahma et al (2015), PLoS ONE http://dx.doi.org/10.1371/journal.pone.0144741
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum bactericidal activities. In this study, we investigated the diversity and biological activity of cathelicidins of buffalo, a species known for its disease resistance. A series of new homologs of cathelicidin4 (CATHL4), which were structurally diverse in their antimicrobial domain, was identified in buffalo. AMPs of newly identified buffalo CATHL4s (buCATHL4s) displayed potent antimicrobial activity against selected Gram positive (G+) and Gram negative (G-) bacteria. These peptides were prompt to disrupt the membrane integrity...
published: 16 Dec 2015
-
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
published: 22 Jun 2011
9:08
#LL37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video 1
#LL37 #alarmin #psoriasis LL-37 has attracted increased attention due to its contribution to the development of inflammatory & autoimmune disorders, such as sys...
#LL37 #alarmin #psoriasis LL-37 has attracted increased attention due to its contribution to the development of inflammatory & autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis , psoriasis, atopic dermatitis & atherosclerosis. LL-37 is a proteolytic fragment of cathelicidin which works as a defensin by inserting into the membranes of bacterial pathogens, and as alarmin in stimulating chemotaxis of innate immune cells, & alters the structure & efficacy of various cytokines.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/in/naglaa-na...
https://wn.com/Ll37_(Antimicrobial_Peptide_Derived_From_Cathelicidin)_Netosis_Video_1
#LL37 #alarmin #psoriasis LL-37 has attracted increased attention due to its contribution to the development of inflammatory & autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis , psoriasis, atopic dermatitis & atherosclerosis. LL-37 is a proteolytic fragment of cathelicidin which works as a defensin by inserting into the membranes of bacterial pathogens, and as alarmin in stimulating chemotaxis of innate immune cells, & alters the structure & efficacy of various cytokines.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/in/naglaa-na...
- published: 16 Jan 2023
- views: 623
13:02
L2.12: Mechanism of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
#immunology #neutrophils #antimicrobial #mechanismofaction
This is the 12th video of chapter 2 of immunology and focuses on the secondary granules in Neutrophi...
#immunology #neutrophils #antimicrobial #mechanismofaction
This is the 12th video of chapter 2 of immunology and focuses on the secondary granules in Neutrophils and mechanisms of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
The links to the other 11 videos are the following
L2.1: Immunology; Hematopoiesis; Hematopoietic Stem Cell and Common Myeloid-Erythroid Progenitor
https://youtu.be/vpb_XN5o60k
L2.2: Immunology; Hematopoiesis; Hematopoietic Stem Cell (HSC) and Common Lymphoid Progenitor
https://youtu.be/O4l4s1QwwQ0
L2.3: Immunology; Granulocytes and Agranulocytes; A quick review
https://youtu.be/bvPw4QWu7zE
L2.4: Immunology; Neutrophils; The first line defender/Granulopoiesis/Geimsa stain
https://youtu.be/cwfRiE7JEj8
L2.5: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Myeloperoxidase
https://youtu.be/Ub5wFPRUu8g
L2.6: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Defensins
https://youtu.be/bLVLO4Ne3GA
L2.7: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Lysozymes
https://youtu.be/SRexXAbRzCA
L2.8: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Elastase
https://youtu.be/ZgJ6rGJ-zfg
L2.9: Function of Cathepsins
https://youtu.be/4BHw0Uxs-AA
L2.10: Function of Lactoferrin (Secondary Granules in Neutrophils)
https://youtu.be/BECFTjTUXvI
L2.11: Mechanism of action of Collagenase and Lysozymes (Secondary Granules in Neutrophils)
https://youtu.be/N3ODHu1B6o0
Cationic Antimicrobial Proteins (CAPs)
The secondary granules or specific granules in neutrophils contain CAPs including defensins, lysozymes, and Cathelicidins.
The CAPs are characterized by their positive net charge
Cathelicidins are a family of antimicrobial peptides that are stored in neutrophil granules as inactive precursors called pro-cathelicidins.
Upon activation by proteolytic cleavage (removal of pro-peptide region), cathelicidins release active peptides that exhibit antimicrobial activity by disrupting microbial membranes and also modulating immune responses.
Cathelicidins exhibit broad-spectrum antimicrobial activity against bacteria, fungi, and some enveloped viruses
In humans, the most extensively studied cathelicidin is LL-37 (+6), derived from the precursor protein hCAP18 (human cationic antimicrobial protein 18)
Mechanism of Action
Cathelicidins like LL-37 possess an amphipathic structure (have both hydrophobic and hydrophilic regions) and this amphipathic nature allows them to interact with lipid bilayers of microbial membranes.
Upon encountering a microbial membrane, LL-37 is inserted into the lipid bilayer, with its hydrophobic regions buried within the lipid acyl chains and their cationic regions oriented towards the membrane surface.
The interaction of LL-37 with microbial membranes leads to the formation of pores and compromises the integrity and permeability of the membrane.
This causes leakage of intracellular contents and ultimately leads to microbial cell death.
The pore-forming activity of cathelicidins is often associated with their ability to oligomerize or aggregate on the membrane surface, leading to the formation of transmembrane pores or defects.
LL-37 can also interact with intracellular targets in bacteria, such as DNA and proteins, disrupting essential cellular processes.
How Selective Targeting is Achieved
Cathelicidins exhibit selective targeting of microbial membranes over mammalian cell membranes.
This selectivity is attributed to differences in membrane composition between microbial and mammalian cells, such as differences in lipid composition and surface charge.
Microbial membranes typically contain a higher proportion of negatively charged lipids, such as phosphatidylglycerol and cardiolipin, which provide electrostatic interactions with the positively charged cationic regions of cathelicidins, facilitating their binding and membrane disruption.
https://wn.com/L2.12_Mechanism_Of_Action_Of_Elastase_And_Cationic_Antimicrobial_Proteins_Cathelicidins_Ll_37
#immunology #neutrophils #antimicrobial #mechanismofaction
This is the 12th video of chapter 2 of immunology and focuses on the secondary granules in Neutrophils and mechanisms of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
The links to the other 11 videos are the following
L2.1: Immunology; Hematopoiesis; Hematopoietic Stem Cell and Common Myeloid-Erythroid Progenitor
https://youtu.be/vpb_XN5o60k
L2.2: Immunology; Hematopoiesis; Hematopoietic Stem Cell (HSC) and Common Lymphoid Progenitor
https://youtu.be/O4l4s1QwwQ0
L2.3: Immunology; Granulocytes and Agranulocytes; A quick review
https://youtu.be/bvPw4QWu7zE
L2.4: Immunology; Neutrophils; The first line defender/Granulopoiesis/Geimsa stain
https://youtu.be/cwfRiE7JEj8
L2.5: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Myeloperoxidase
https://youtu.be/Ub5wFPRUu8g
L2.6: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Defensins
https://youtu.be/bLVLO4Ne3GA
L2.7: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Lysozymes
https://youtu.be/SRexXAbRzCA
L2.8: Immunology; Neutrophils/ Granules/Primary Granules/Azurophilic granules/Elastase
https://youtu.be/ZgJ6rGJ-zfg
L2.9: Function of Cathepsins
https://youtu.be/4BHw0Uxs-AA
L2.10: Function of Lactoferrin (Secondary Granules in Neutrophils)
https://youtu.be/BECFTjTUXvI
L2.11: Mechanism of action of Collagenase and Lysozymes (Secondary Granules in Neutrophils)
https://youtu.be/N3ODHu1B6o0
Cationic Antimicrobial Proteins (CAPs)
The secondary granules or specific granules in neutrophils contain CAPs including defensins, lysozymes, and Cathelicidins.
The CAPs are characterized by their positive net charge
Cathelicidins are a family of antimicrobial peptides that are stored in neutrophil granules as inactive precursors called pro-cathelicidins.
Upon activation by proteolytic cleavage (removal of pro-peptide region), cathelicidins release active peptides that exhibit antimicrobial activity by disrupting microbial membranes and also modulating immune responses.
Cathelicidins exhibit broad-spectrum antimicrobial activity against bacteria, fungi, and some enveloped viruses
In humans, the most extensively studied cathelicidin is LL-37 (+6), derived from the precursor protein hCAP18 (human cationic antimicrobial protein 18)
Mechanism of Action
Cathelicidins like LL-37 possess an amphipathic structure (have both hydrophobic and hydrophilic regions) and this amphipathic nature allows them to interact with lipid bilayers of microbial membranes.
Upon encountering a microbial membrane, LL-37 is inserted into the lipid bilayer, with its hydrophobic regions buried within the lipid acyl chains and their cationic regions oriented towards the membrane surface.
The interaction of LL-37 with microbial membranes leads to the formation of pores and compromises the integrity and permeability of the membrane.
This causes leakage of intracellular contents and ultimately leads to microbial cell death.
The pore-forming activity of cathelicidins is often associated with their ability to oligomerize or aggregate on the membrane surface, leading to the formation of transmembrane pores or defects.
LL-37 can also interact with intracellular targets in bacteria, such as DNA and proteins, disrupting essential cellular processes.
How Selective Targeting is Achieved
Cathelicidins exhibit selective targeting of microbial membranes over mammalian cell membranes.
This selectivity is attributed to differences in membrane composition between microbial and mammalian cells, such as differences in lipid composition and surface charge.
Microbial membranes typically contain a higher proportion of negatively charged lipids, such as phosphatidylglycerol and cardiolipin, which provide electrostatic interactions with the positively charged cationic regions of cathelicidins, facilitating their binding and membrane disruption.
- published: 30 Mar 2024
- views: 60
12:50
What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
Hello Everyone
Today's video is : What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
If you like my 'What A...
Hello Everyone
Today's video is : What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
If you like my 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video, please give it a big thumbs up.
If you found this 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video useful, please consider subscribing.
Also, if you'd like to see more videos like 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' leave me a comment below.
Topic: What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
Tags: Medical Videos, Medical Lectures, dental emergency, dental periodontal lecture, perio hub, antimicrobial peptides, AMP, histadins, defensins, perioqueries.
WATCH OUR OTHER VIDEOS
Dental Plaque : https://www.youtube.com/watch?v=Afn2H...
Gingiva : https://www.youtube.com/watch?v=Afn2H...
Alveolar bone : https://www.youtube.com/watch?v=jVjuP...
Cementum : https://www.youtube.com/watch?v=m1oKv...
Periodontal ligament : https://www.youtube.com/watch?v=ADOqC...
STAY CONNECTED
» Instagram: https://www.instagram.com/periohub/
» Facebook: https://www.facebook.com/periohub1402/
» LinkedIn: https://www.linkedin.com/in/dr-sneha-...
» Gmail :
[email protected]
#antimicrobialpeptides
#periohub
#perioqueries
https://wn.com/What_Are_Anti_Microbial_Peptides_‖_Antimicrobial_Peptides_In_Periodontics_‖_Perioqueries‖_Dr.Sneha
Hello Everyone
Today's video is : What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
If you like my 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video, please give it a big thumbs up.
If you found this 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' video useful, please consider subscribing.
Also, if you'd like to see more videos like 'What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha' leave me a comment below.
Topic: What Are Anti-Microbial Peptides ??‖ Antimicrobial Peptides in Periodontics ‖#perioqueries‖ Dr.Sneha
Tags: Medical Videos, Medical Lectures, dental emergency, dental periodontal lecture, perio hub, antimicrobial peptides, AMP, histadins, defensins, perioqueries.
WATCH OUR OTHER VIDEOS
Dental Plaque : https://www.youtube.com/watch?v=Afn2H...
Gingiva : https://www.youtube.com/watch?v=Afn2H...
Alveolar bone : https://www.youtube.com/watch?v=jVjuP...
Cementum : https://www.youtube.com/watch?v=m1oKv...
Periodontal ligament : https://www.youtube.com/watch?v=ADOqC...
STAY CONNECTED
» Instagram: https://www.instagram.com/periohub/
» Facebook: https://www.facebook.com/periohub1402/
» LinkedIn: https://www.linkedin.com/in/dr-sneha-...
» Gmail :
[email protected]
#antimicrobialpeptides
#periohub
#perioqueries
- published: 02 Oct 2020
- views: 13229
17:29
Generation and Structure of Human Cathelicidin LL37
#dermaimmunology #LL37 #Cathelicidin
LL-37 acts as an antimicrobial peptide & also as an immunomodulator, potentially CONTRIBUTING TO the onset of autoimmune...
#dermaimmunology #LL37 #Cathelicidin
LL-37 acts as an antimicrobial peptide & also as an immunomodulator, potentially CONTRIBUTING TO the onset of autoimmune diseases. LL-37 is the only Cathelicidin member in humans.
🔔Subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388365/
Key moments"
00:00 Introduction
02:35 LL37 Generation
11:35 LL37 Structure
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
For more information:
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/feed/?trk=ms...
https://wn.com/Generation_And_Structure_Of_Human_Cathelicidin_Ll37
#dermaimmunology #LL37 #Cathelicidin
LL-37 acts as an antimicrobial peptide & also as an immunomodulator, potentially CONTRIBUTING TO the onset of autoimmune diseases. LL-37 is the only Cathelicidin member in humans.
🔔Subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388365/
Key moments"
00:00 Introduction
02:35 LL37 Generation
11:35 LL37 Structure
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
For more information:
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/feed/?trk=ms...
- published: 14 Nov 2023
- views: 116
0:16
#shorts LL-37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video #2
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
https://wn.com/Shorts_Ll_37_(Antimicrobial_Peptide_Derived_From_Cathelicidin)_Netosis_Video_2
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
- published: 18 Sep 2023
- views: 61
9:08
LL-37 (antimicrobial peptide derived from cathelicidin) & NETOSIS video #2
#LL-37 has an affinity for phospholipid membranes. So, LL-37 contributes to the nuclear membrane disruption & the formation of #NETs. LL-37 in combination with...
#LL-37 has an affinity for phospholipid membranes. So, LL-37 contributes to the nuclear membrane disruption & the formation of #NETs. LL-37 in combination with DNA or RNA may contribute to a self-sustaining & amplifying vicious cycle of ongoing & progressive chronic #inflammation. LL-37 peptide-containing complexes, in which LL-37 protects NET-derived DNA from degradation accumulation of immunogenic NETs & induction of anti-NET antibodies.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
key moments:
00:00 Introduction
02:40 LL-37 in psoriasis
03:27 LL-37 in LE
05:49 LL-37 in other Autoimmune & Inflammatory CONDITIONS
07:47 LL-37 Final notes
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/in/naglaa-na...
https://wn.com/Ll_37_(Antimicrobial_Peptide_Derived_From_Cathelicidin)_Netosis_Video_2
#LL-37 has an affinity for phospholipid membranes. So, LL-37 contributes to the nuclear membrane disruption & the formation of #NETs. LL-37 in combination with DNA or RNA may contribute to a self-sustaining & amplifying vicious cycle of ongoing & progressive chronic #inflammation. LL-37 peptide-containing complexes, in which LL-37 protects NET-derived DNA from degradation accumulation of immunogenic NETs & induction of anti-NET antibodies.
🔔subscribe for more free Derma Immunology videos: https://www.youtube.com/@dermaimmunology/featured
REFERENCE:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368159/#:~:text=The%20LL%2D37%20peptide%20is,dsDNA%20and%20to%20LL%2D37.
key moments:
00:00 Introduction
02:40 LL-37 in psoriasis
03:27 LL-37 in LE
05:49 LL-37 in other Autoimmune & Inflammatory CONDITIONS
07:47 LL-37 Final notes
PLAYLISTS:
https://www.youtube.com/watch?v=xAu2c1FOVeA&list=PLPXT4Vm87xRr8BJ-BOIlDs1wciqufQhw6
https://www.youtube.com/watch?v=vRumDsHJVCc&list=PLPXT4Vm87xRrKY_nZEFU4nhMQiBkXDUk5
https://www.youtube.com/watch?v=gDz9sqHOfX8&list=PLPXT4Vm87xRoE8dYCWNi-EITfeUu7kG_m
https://www.youtube.com/watch?v=eRnGK01ffME
https://www.youtube.com/watch?v=HA9xh4002Hs&list=PLPXT4Vm87xRrSGV-W5EFJRE6aVdJW-ayV
https://www.youtube.com/watch?v=oFR1D5W6k14&list=PLPXT4Vm87xRpLsvDjNTl20Sv36IMBctID
https://www.youtube.com/watch?v=1WxcOIX9Dvg&list=PLPXT4Vm87xRoP1u3Vil8QzVoYvPJItqa3
https://www.youtube.com/watch?v=RlLsG9mB9iM&list=PLPXT4Vm87xRpazVaOXIEecnC9ame0nQTX
https://www.youtube.com/watch?v=C6r2p1_3FyA&list=PLPXT4Vm87xRpkdiG8rvS-O2PxHzFluqSd
https://www.youtube.com/watch?v=156Fr_IOwic&list=PLPXT4Vm87xRqXKfoQdERZjvJIBI5qI5zI
https://www.youtube.com/watch?v=pti4JBTC_Sw&list=PLPXT4Vm87xRrkfjS3Juouf2Ue2hdqV-Nw
https://www.youtube.com/watch?v=PjlRnRTTyMg&list=PLPXT4Vm87xRrTJHr6EvcVaq8YSBT0xHOE
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
https://www.youtube.com/watch?v=epX6qnkqRV8&list=PLPXT4Vm87xRq5kyrgPGOqLoejpIi0IeYZ
https://www.youtube.com/watch?v=ycHVN8pr5NM&list=PLPXT4Vm87xRr4i4mbPEz9TwCVYuw3EJ-v
Web site: https://dermatologytrend.com
Facebook page: https://www.facebook.com/dermatoltrend
LinkedIn: https://www.linkedin.com/in/naglaa-na...
- published: 20 Jan 2023
- views: 499
3:56
Cathelicidins: Vitamin D's antimicrobial arsenal
Today, I detail the antimicrobial proteins Cathelicidins, and how they are dependent on adequate vitamin D intake. I also show you how to enhance the function ...
Today, I detail the antimicrobial proteins Cathelicidins, and how they are dependent on adequate vitamin D intake. I also show you how to enhance the function of any supplemental vitamin D you're taking.
ENZYMENTAL Episode 185
Motion graphics by http://www.canva.com
#enzymental #jasoncarter #stayhealthy
https://wn.com/Cathelicidins_Vitamin_D's_Antimicrobial_Arsenal
Today, I detail the antimicrobial proteins Cathelicidins, and how they are dependent on adequate vitamin D intake. I also show you how to enhance the function of any supplemental vitamin D you're taking.
ENZYMENTAL Episode 185
Motion graphics by http://www.canva.com
#enzymental #jasoncarter #stayhealthy
- published: 25 Feb 2022
- views: 703
34:11
Joshua McClure - Antimicrobial Peptoids: Next Generation Anti-infectives
MaxWell Bioscience's mission is to prove our disruptive new "peptoid" anti-infectives destroy humanity's top threat - highly infectious pandemic microbes - like...
MaxWell Bioscience's mission is to prove our disruptive new "peptoid" anti-infectives destroy humanity's top threat - highly infectious pandemic microbes - like untreatable viruses, drug-resistant bacteria, and drug-resistant fungi. Maxwell's anti-infectives have been shown by multiple independent labs (including Stanford, NYU and others) to be rapid killers of the worst viruses, drug-resistant fungi and treatment-resistant bacteria. These labs show Maxwell peptoids are highly selective for pathogens over human cells, are biostable, effective at low doses, and rapidly destroy biofilm defenses. MaxWell Bioscience are in preclinical stage now, preparing for human trials.
https://maxwellbiosciences.com
Joshua McClure is Founder and CEO of MaxWell Biosciences. Joshua has co-invented and secured over a dozen patents in the areas of multi-tissue regeneration and gene expression modulation in collaboration with co-inventors at Stanford University, and University of California Berkeley. McClure leads a team of some of the world's top scientists and clinicians in the field of tissue regeneration, using computational systems medicine to personalize therapies.
A graduate of the USAF Academy, McClure has been a leader of tech companies for over 15 years and comes to industry with a background in top secret USAF projects. He has invented multiple new category-first companies, revolutionary new technologies and now devotes his time to biotechnologies with the capacity to reverse age-related degeneration, and optimize human longevity. MaxWell is working with Mayo Clinic, The American Red Cross and others to bring these technologies to humans.
https://www.linkedin.com/in/joshuamcclure
Many thanks for watching!
Consider supporting SciFuture by:
a) Subscribing to the SciFuture YouTube channel: http://youtube.com/subscription_center?add_user=TheRationalFuture
b) Donating
- Bitcoin: 1BxusYmpynJsH4i8681aBuw9ZTxbKoUi22
- Etheriem: 0xd46a6e88c4fe179d04464caf42626d0c9cab1c6b
- Patreon: https://www.patreon.com/scifuture
c) Sharing the media SciFuture creates: http://scifuture.org
Kind regards,
Adam Ford
- Science, Technology & the Future
https://wn.com/Joshua_Mcclure_Antimicrobial_Peptoids_Next_Generation_Anti_Infectives
MaxWell Bioscience's mission is to prove our disruptive new "peptoid" anti-infectives destroy humanity's top threat - highly infectious pandemic microbes - like untreatable viruses, drug-resistant bacteria, and drug-resistant fungi. Maxwell's anti-infectives have been shown by multiple independent labs (including Stanford, NYU and others) to be rapid killers of the worst viruses, drug-resistant fungi and treatment-resistant bacteria. These labs show Maxwell peptoids are highly selective for pathogens over human cells, are biostable, effective at low doses, and rapidly destroy biofilm defenses. MaxWell Bioscience are in preclinical stage now, preparing for human trials.
https://maxwellbiosciences.com
Joshua McClure is Founder and CEO of MaxWell Biosciences. Joshua has co-invented and secured over a dozen patents in the areas of multi-tissue regeneration and gene expression modulation in collaboration with co-inventors at Stanford University, and University of California Berkeley. McClure leads a team of some of the world's top scientists and clinicians in the field of tissue regeneration, using computational systems medicine to personalize therapies.
A graduate of the USAF Academy, McClure has been a leader of tech companies for over 15 years and comes to industry with a background in top secret USAF projects. He has invented multiple new category-first companies, revolutionary new technologies and now devotes his time to biotechnologies with the capacity to reverse age-related degeneration, and optimize human longevity. MaxWell is working with Mayo Clinic, The American Red Cross and others to bring these technologies to humans.
https://www.linkedin.com/in/joshuamcclure
Many thanks for watching!
Consider supporting SciFuture by:
a) Subscribing to the SciFuture YouTube channel: http://youtube.com/subscription_center?add_user=TheRationalFuture
b) Donating
- Bitcoin: 1BxusYmpynJsH4i8681aBuw9ZTxbKoUi22
- Etheriem: 0xd46a6e88c4fe179d04464caf42626d0c9cab1c6b
- Patreon: https://www.patreon.com/scifuture
c) Sharing the media SciFuture creates: http://scifuture.org
Kind regards,
Adam Ford
- Science, Technology & the Future
- published: 22 Dec 2019
- views: 3004
0:57
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. Biswajit Brahma et al (2015), PLoS ONE http://dx.doi.org/10.1371/j...
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. Biswajit Brahma et al (2015), PLoS ONE http://dx.doi.org/10.1371/journal.pone.0144741
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum bactericidal activities. In this study, we investigated the diversity and biological activity of cathelicidins of buffalo, a species known for its disease resistance. A series of new homologs of cathelicidin4 (CATHL4), which were structurally diverse in their antimicrobial domain, was identified in buffalo. AMPs of newly identified buffalo CATHL4s (buCATHL4s) displayed potent antimicrobial activity against selected Gram positive (G+) and Gram negative (G-) bacteria. These peptides were prompt to disrupt the membrane integrity of bacteria and induced specific changes such as blebing, budding, and pore like structure formation on bacterial membrane. The peptides assumed different secondary structure conformations in aqueous and membrane-mimicking environments. Simulation studies suggested that the amphipathic design of buCATHL4 was crucial for water permeation following membrane disruption. A great diversity, broad-spectrum antimicrobial action, and ability to induce an inflammatory response indicated the pleiotropic role of cathelicidins in innate immunity of buffalo. This study suggests short buffalo cathelicidin peptides with potent bactericidal properties and low cytotoxicity have potential translational applications for the development of novel antibiotics and antimicrobial peptidomimetics.
Good channel: https://www.youtube.com/Dlium
Subscribe, like and comment.
Good website: https://www.dlium.com
Bookmark, subscribe and comment.
https://wn.com/Diversity,_Antimicrobial_Action_And_Structure_Activity_Relationship_Of_Buffalo_Cathelicidins
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. Biswajit Brahma et al (2015), PLoS ONE http://dx.doi.org/10.1371/journal.pone.0144741
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum bactericidal activities. In this study, we investigated the diversity and biological activity of cathelicidins of buffalo, a species known for its disease resistance. A series of new homologs of cathelicidin4 (CATHL4), which were structurally diverse in their antimicrobial domain, was identified in buffalo. AMPs of newly identified buffalo CATHL4s (buCATHL4s) displayed potent antimicrobial activity against selected Gram positive (G+) and Gram negative (G-) bacteria. These peptides were prompt to disrupt the membrane integrity of bacteria and induced specific changes such as blebing, budding, and pore like structure formation on bacterial membrane. The peptides assumed different secondary structure conformations in aqueous and membrane-mimicking environments. Simulation studies suggested that the amphipathic design of buCATHL4 was crucial for water permeation following membrane disruption. A great diversity, broad-spectrum antimicrobial action, and ability to induce an inflammatory response indicated the pleiotropic role of cathelicidins in innate immunity of buffalo. This study suggests short buffalo cathelicidin peptides with potent bactericidal properties and low cytotoxicity have potential translational applications for the development of novel antibiotics and antimicrobial peptidomimetics.
Good channel: https://www.youtube.com/Dlium
Subscribe, like and comment.
Good website: https://www.dlium.com
Bookmark, subscribe and comment.
- published: 16 Dec 2015
- views: 784
14:35
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
https://wn.com/Dr._Gerry_Schwalffenberg_Part_1_Of_3_Vitamin_D_Seminar,_Edmonton_Canada,_April_28,_2011
Dr. Gerry Schwalffenberg Part 1 of 3 - Vitamin D Seminar, Edmonton Canada, April 28, 2011
- published: 22 Jun 2011
- views: 1602