Извор странице CD97

{{PBB|geneid=976}}
'''-{CD97}- antigen''' je [[protein]] koji je kod ljudi kodiran -{''CD97''}- [[gen]]om.<ref name="pmid7636245">{{cite journal |vauthors=Hamann J, Eichler W, Hamann D, Kerstens HM, Poddighe PJ, Hoovers JM, Hartmann E, Strauss M, van Lier RA | title = Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain | journal = J Immunol | volume = 155 | issue = 4 | pages = 1942–50 | year = 1995 | pmid = 7636245 | pmc =  | doi =  }}</ref><ref name="pmid8786105">{{cite journal |vauthors=Hamann J, Hartmann E, van Lier RA | title = Structure of the human CD97 gene: exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily | journal = Genomics | volume = 32 | issue = 1 | pages = 144–7 | year = 1996 | pmid = 8786105 | pmc =  | doi = 10.1006/geno.1996.0092 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CD97 CD97 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=976| accessdate = }}</ref>

Ovaj gen je član -{EGF-TM7}- familije klase II sedam transmembranskih (7-TM) molekula. On je kodiran genskim klusterom na kratkoj ruci [[hromozom]]a 19. -{CD97}- je glikoprotein koji je prisutan na površini aktiviranih [[leukocit]]a. Njegov ekstracelularni region sadrži nekoliko [[N-terminus|-{N}--terminalnih]] domena sličnih epidermalnom faktoru rasta, koji posreduju vezivanje njegovog liganda, faktora ubrzanja raspada ({{jez-eng-lat|decay accelerating factor}}) (-{DAF, CD55}-), regulatornog proteina komplementne kaskade. Prisustvo strukturnih osobina karakterističnih za proteine [[Екстрацелуларни матрикс|ekstracelularnog matriksa]] i [[Transmembranski receptor|transmembranske proteine]] sugeriše da ovaj receptor učestvuje u ćelijskoj adheziji i signalizaciji nakon aktivacije leukocita. Poznate su tri [[alternativno splajsovanje|alternativno splajsovane]] varijante.<ref name="entrez" />

==Reference==
{{reflist|2}}

==Literature==
{{Литература | 2}}
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{{Литература крај}}
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{{PDB Galerija-lat|geneid=976}}
{{Klasteri diferencijacije-lat}}
{{G protein spregnuti receptori-lat}}

{{normativna kontrola}}

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