MPPF

MPPF
	4-Fluoro-N-[2-[4-(2-metoksifenil)-1-piperazinil]etil]-N-(2-piridil)benzamid
Identifikacija
CAS registarski broj	155204-26-5
PubChem	6603915
Jmol-3D slike	Slika 1
SMILES
	COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4=CC=C(C=C4)F
Svojstva
Molekulska formula	C25H27FN4O2
Molarna masa	434,51 g/mol
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

MPPF (2'-metoksifenil-(N-2'-piridinil)-p-fluoro-benzamidoetilipiperazin) je jedinjenje koje se vezuje za serotoninski 1A receptor. Obeležen sa fluorom-18 on je korišten kao radioligand za pozitronsku emisionu tomografiju.^[3] On je između ostalog bio korišten za ispitivanje razlika vezivanja za neuroreceptore u ljudskom mozgu kod osoba različitog pola i uzrasta.^[4]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ D. Le Bars (May 1998). „High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635”. Nuclear Medicine and Biology 25 (4): 343–350. DOI:10.1016/S0969-8051(97)00229-1.
↑ Nicolas Costes; Merlet, I; Ostrowsky, K; Faillenot, I; Lavenne, F; Zimmer, L; Ryvlin, P; Le Bars, D (December 2005). „A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging”. the Journal of Nuclear Medicine 46 (12): 1980–1989. PMID 16330560.

Povezano

WAY-100,635

Spoljašnje veze

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] D. Le Bars (May 1998). „High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635”. Nuclear Medicine and Biology 25 (4): 343–350. DOI:10.1016/S0969-8051(97)00229-1.

[4] Nicolas Costes; Merlet, I; Ostrowsky, K; Faillenot, I; Lavenne, F; Zimmer, L; Ryvlin, P; Le Bars, D (December 2005). „A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging”. the Journal of Nuclear Medicine 46 (12): 1980–1989. PMID 16330560.

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