Review
doi: 10.1097/00041433-199602000-00011.
n-3 polyunsaturated fatty acids and human cytokine synthesis
Affiliations
- PMID: 8925190
- DOI: 10.1097/00041433-199602000-00011
Item in Clipboard
Review
n-3 polyunsaturated fatty acids and human cytokine synthesis
Curr Opin Lipidol.
1996 Feb.
Abstract
The cytokines interleukin-1 and tumor necrosis factor contribute to the pathogenesis of inflammatory diseases and, potentially, to atherogenesis. The synthesis of these cytokines in humans can be suppressed by oral intake of n-3 polyunsaturated fatty acids. This mechanism may contribute to the beneficial effect of long-term n-3 fatty acid supplementation in inflammatory diseases such as renal transplant rejection, immunoglobulin A nephropathy and rheumatoid arthritis.
Similar articles
-
n-3 polyunsaturated fatty acids in the regulation of human cytokine synthesis.Biochem Soc Trans. 1995 May;23(2):277-81. doi: 10.1042/bst0230277a. Biochem Soc Trans. 1995. PMID: 7672303 Review. No abstract available.
-
n-3 polyunsaturated fatty acids and human cytokine synthesis.Lipids. 1996 Mar;31 Suppl:S239-42. doi: 10.1007/BF02637083. Lipids. 1996. PMID: 8729126 Review.
-
Rheumatoid arthritis and the balance of dietary N-6 and N-3 essential fatty acids.Br J Rheumatol. 1997 May;36(5):513-4. doi: 10.1093/rheumatology/36.5.513. Br J Rheumatol. 1997. PMID: 9189049 No abstract available.
-
Effects of omega 3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen.World Rev Nutr Diet. 1991;66:401-6. doi: 10.1159/000419308. World Rev Nutr Diet. 1991. PMID: 2053356 No abstract available.
-
N-3 polyunsaturated fatty acids restore Th17 and Treg balance in collagen antibody-induced arthritis.PLoS One. 2018 Mar 15;13(3):e0194331. doi: 10.1371/journal.pone.0194331. eCollection 2018. PLoS One. 2018. PMID: 29543869 Free PMC article.
Cited by
-
Regulation of Inflammasomes by Application of Omega-3 Polyunsaturated Fatty Acids in a Spinal Cord Injury Model.Cells. 2021 Nov 12;10(11):3147. doi: 10.3390/cells10113147. Cells. 2021. PMID: 34831370 Free PMC article.
-
Free fatty acids, cardiovascular disease, and mortality in the Multi-Ethnic Study of Atherosclerosis.J Clin Lipidol. 2020 Jul-Aug;14(4):531-541. doi: 10.1016/j.jacl.2020.06.005. Epub 2020 Jun 10. J Clin Lipidol. 2020. PMID: 32651087 Free PMC article.
-
Fish oil for kidney transplant recipients.Cochrane Database Syst Rev. 2016 Aug 18;2016(8):CD005282. doi: 10.1002/14651858.CD005282.pub3. Cochrane Database Syst Rev. 2016. PMID: 27535773 Free PMC article. Review.
-
Omega-3 fatty acids' effect on leptin and adiponectin concentrations in patients with spinal cord injury: A double-blinded randomized clinical trial.J Spinal Cord Med. 2015 Sep;38(5):599-606. doi: 10.1179/2045772314Y.0000000251. Epub 2014 Aug 6. J Spinal Cord Med. 2015. PMID: 25096818 Free PMC article. Clinical Trial.
-
Ethnicity, plasma phospholipid fatty acid composition and inflammatory/endothelial activation biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).Eur J Clin Nutr. 2012 May;66(5):600-5. doi: 10.1038/ejcn.2011.215. Epub 2012 Jan 4. Eur J Clin Nutr. 2012. PMID: 22215136 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources