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Clinical Trial
. 1988 Jan;118(1):77-83.
doi: 10.1111/j.1365-2133.1988.tb01753.x.

Effect of dietary supplementation with n-3 fatty acids on clinical manifestations of psoriasis

A Bjørneboe  1 , A K Smith, G E Bjørneboe, P O Thune, C A Drevon
Affiliations
Clinical Trial

Effect of dietary supplementation with n-3 fatty acids on clinical manifestations of psoriasis

A Bjørneboe et al. Br J Dermatol. 1988 Jan.

Abstract

In a double-blind, block randomized study we investigated the effect of dietary supplementation with eicosapentaenoic acid in patients with psoriasis. The experimental group received 10 g of fish oil daily containing approximately 1.8 g eicosapentaenoic acid, while the controls were given an isoenergetic amount of olive oil. We found no significant change in the clinical manifestations of psoriasis in either group after 8 weeks of treatment. In the experimental group, the amount of n-3 fatty acids in serum phospholipids was significantly increased at the end of trial as compared to pre-treatment values, whereas the level of n-6 fatty acids was decreased.

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