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A. BJØRNEBOE, ANNE KLEMEYER SMITH, GUNN‐ELIN AA. BJØRNEBOE, P.O. THUNE, C.A. DREVON, Effect of dietary supplementation with n‐3 fatty acids on clinical manifestations of psoriasis, British Journal of Dermatology, Volume 118, Issue 1, 1 January 1988, Pages 77–83, https://doi.org/10.1111/j.1365-2133.1988.tb01753.x
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In a double‐blind, block randomized study we investigated the effect of dietary supplementation with eicosapentaenoic acid in patients with psoriasis. The experimental group received 10 g of fish oil daily containing approximately 1.8 g eicosapentaenoic acid, while the controls were given an isoenergetic amount of olive oil. We found no significant change in the clinical manifestations of psoriasis in either group after 8 weeks of treatment. In the experimental group, the amount of n‐3 fatty acids in serum phospholipids was significantly increased at the end of trial as compared to pre‐treatment values, whereas the level of n‐6 fatty acids was decreased.