GIMAP5

GIMAP5
식별자
다른 이름	GIMAP5, HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD, GTPase, IMAP family member 5, NCPH2
외부 ID	OMIM: 608086 MGI: 1932723 GeneCards: GIMAP5
유전자 위치 (인간)
염색체	7번 염색체
끝	150,750,033 bp
유전자 위치 (쥐)
염색체	6번 염색체 (쥐)
끝	48,747,785 bp
RNA 발현 패턴
	최상위 발현
	오른허파; ; 과립구; ; upper lobe of left lung; ; 비장; ; 림프절; ; apex of heart; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; 아킬레스건; ; gastric mucosa;
	최상위 발현
	림프절; ; mesenteric lymph nodes; ; 비장; ; 혈액; ; 가슴샘; ; subcutaneous adipose tissue; ; 샘창자; ; 오른허파; ; 과립구; ; 턱밑샘;
	추가 참조 발현 데이터
	; ;
	추가 참조 발현 데이터
동원체
	55340
	83408
	ENSG00000196329
	ENSMUSG00000039264
	Q96F15
	Q99MI6
	NM_018384
	NM_031247
	NP_060854; NP_060854.2
	NP_112537
	위키데이터
인간 보기/편집	쥐 보기/편집

GTP 가수분해효소 IMAP Family Member 5(GTPase IMAP family member 5)는 인간에서 GIMAP5 유전자에 의해 암호화되는 효소이다.^[5]

이 유전자는 GTP 결합 및 뉴클레오타이드 결합 단백질의 면역 관련 뉴클레오타이드(IAN) 서브 패밀리에 속하는 단백질을 암호화한다. 인간에서 IAN 서브 패밀리 유전자는 7q36.1의 클러스터에 위치한다.^[5]

각주

↑ ^가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000196329 - 앙상블, May 2017
↑ ^가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000039264 - 앙상블, May 2017
↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ ^가 ^나 “Entrez Gene: GIMAP5 GTPase, IMAP family member 5”.

추가 자료

“Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity.”. 《Nucleic Acids Res.》 29 (6): 1308–16. 2001. doi:10.1093/nar/29.6.1308. PMC 29751. PMID 11238997.
“Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36.”. 《Gene》 282 (1–2): 159–67. 2002. doi:10.1016/S0378-1119(01)00837-X. PMID 11814688.
“Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells”. 《Blood》 99 (9): 3293–301. 2002. doi:10.1182/blood.V99.9.3293. PMID 11964296.
“Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. 《Proc. Natl. Acad. Sci. U.S.A.》 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
“Human chromosome 7: DNA sequence and biology”. 《Science》 300 (5620): 767–72. 2003. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
“Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis”. 《Mol. Biol. Cell》 14 (8): 3292–304. 2004. doi:10.1091/mbc.E02-10-0700. PMC 181568. PMID 12925764.
“Complete sequencing and characterization of 21,243 full-length human cDNAs”. 《Nat. Genet.》 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
“hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies”. 《Genes Immun.》 5 (2): 109–16. 2004. doi:10.1038/sj.gene.6364044. PMID 14724691.
“Comparative analysis of the human gimap gene cluster encoding a novel GTPase family”. 《Gene》 341: 291–304. 2005. doi:10.1016/j.gene.2004.07.005. PMID 15474311.
“The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. 《Genome Res.》 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
“The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus”. 《J. Med. Genet.》 44 (5): 314–21. 2007. doi:10.1136/jmg.2006.046185. PMC 2597989. PMID 17220214.
“Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells”. 《Int. Immunol.》 19 (4): 447–53. 2007. doi:10.1093/intimm/dxm009. PMID 17369194.
“IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5”. 《Genes Immun.》 8 (6): 503–12. 2007. doi:10.1038/sj.gene.6364413. PMID 17641683.

[refGRCh38Ensembl-1] 가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000196329 - 앙상블, May 2017

[refGRCm38Ensembl-2] 가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000039264 - 앙상블, May 2017

[3] “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[4] “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[entrez-5] 가 ^나 “Entrez Gene: GIMAP5 GTPase, IMAP family member 5”.

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