December 16, 2024
Image credit: PLOS Computational Biology
01/29/2025
Research Article
The authors present a quantitative approach to evaluating the role of various aspects of data in the emergence of low dimensional, topological, features. Topological features are those that are insensitive to certain deformations of an object, e.g. stretching, but not cutting.
Current Issue January 2025
01/23/2025
Education
However, effective translation of AI and deep learning methods requires computational researchers to have at least a basic understanding of histopathology. This work aims to bridge that gap by introducing essential histopathology concepts to support AI developers in their research.
Image credit: Mandal et al
01/24/2025
Research Article
This study explores how behavioral patterns vary across contexts and alliances. The authors investigate the possibility that resident female and male downy woodpeckers guard their breeding territories from conspecific intruders by deploying defensive behavior in context-specific patterns.
Image credit: Hans Veth
01/23/2025
Research Article
This study proposes a data-driven approach to validate the applicability of mathematical models. The authors developed methods to automatically select the appropriate mathematical models based on the patterns of interest and to estimate the model parameters.
01/10/2025
Education
This paper suggests 10 simple rules for you to both (i) ensure you share models in a way that is at least “good enough,” and (ii) enable others to lead the change towards better model-sharing practices.
Image credit: Fabio (Unsplash)
01/07/2025
Research Article
In many cases, the goal of conducting new experiments in protein design is optimizing for a property or improving the machine learning model. Many standard methods for these two tasks require good estimates of the uncertainty in the model’s predictions.
Image credit: NCI
12/30/2024
Education
This paper provides a step-by-step tutorial to train 4 different ML models to predict drug resistance for E.coli isolates and to evaluate their performance.
Image credit: Wikipedia
12/26/2024
Research Article
This study analyzed the performance of a large and diverse collection of IPD strategies across thousands of computer tournaments. While no single strategy consistently excels, successful strategies share key characteristics.
Image credit: GR Stocks
12/13/2024
Research Article
The authors explore the importance of adapting temporal parameters in spiking neural networks in an evolutionary context, observing that adapting weights by themselves was not sufficient to solve a range of tasks.
Image credit: Wikimedia
12/11/2024
Research Article
OmicSHIELD is introduced as an open-source tool aimed at overcoming challenges in sharing by enabling privacy-protected federated analysis of sensitive omic data.
Image credit: Scott Rogerson
This Collection aims to increase the coverage of computational biology-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.
This series of perspective articles from computational biologists in a variety of countries, offers their personal viewpoint on the history, current status, and future of computational biology in their region.
This collection aims to provide practical tutorials and background information on important computational methods used to investigate key biological questions, as well as resources for training scientists at all stages of their careers.
The Benchmarking collection help readers decide between a number of methods which are developed to solve scientific problems.
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Test accuracy of polymerase chain reaction methods against conventional diagnostic techniques for Cutaneous Leishmaniasis (CL) in patients with clinical or epidemiological suspicion of CL: Systematic review and meta-analysis
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys
Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data
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