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Program for aligning DNA sequences, a pairwise aligner.

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LASTZ - pairwise DNA sequence aligner

This repository contains the latest official working branch of LASTZ. Official releases are tagged, and can be found in https://github.com/lastz/lastz/releases. Users are encouraged to use a tagged release, as this working branch may not be stable.

As of this writing, the latest official release is version 1.04.22. Additional LASTZ releases, including all releases prior to September 2021, can be found at http://www.bx.psu.edu/~rsharris/lastz (in the form of tarballs).

For information about installation and use, see https://lastz.github.io/lastz (equivalent to README.lastz.html in this repository).

The UCSC genome browser group has included lastz and lastz_D in their prebuilt binaries (the version there might lag behind the latest version here):

    http://hgdownload.soe.ucsc.edu/admin/exe/linux.x86_64/
    http://hgdownload.soe.ucsc.edu/admin/exe/macOSX.x86_64/

A GPU accelerated version, KegAlign, can be found at https://github.com/galaxyproject/KegAlign. This improves on an earlier GPU accelerated version, SegAlign, which can be found at https://github.com/gsneha26/SegAlign.

Updated Sep/2/2024 by Bob Harris (the LASTZ guy)