This exemplary initial setup uses two devices /dev/sdb and /dev/sdc but can be applied to any amount of devices by following the steps with additional devices.

Create keyfile:

dd bs=64 count=1 if=/dev/urandom of=/etc/cryptkey iflag=fullblock
chmod 600 /etc/cryptkey

A quick guide on how to setup a GPU-Passthorugh. Below are some of my Resources

• https://wiki.archlinux.org/index.php/PCI_passthrough_via_OVMF
• https://www.evonide.com/non-root-gpu-passthrough-setup/
• https://dominicm.com/gpu-passthrough-qemu-arch-linux/

The Arch Wiki is the goto place for additional information and performance tweaks like CPU-Pinning.

• IGPU or second dedicated GPU for Host system (unless you want to go the hard way and use one GPU for HOST and GUEST)