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DEFB129

From Wikipedia, the free encyclopedia
DEFB129
Identifiers
AliasesDEFB129, C20orf87, DEFB-29, DEFB29, bA530N10.3, hBD-29, defensin beta 129
External IDsMGI: 3644405; HomoloGene: 83411; GeneCards: DEFB129; OMA:DEFB129 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080831

NM_001037933

RefSeq (protein)

NP_543021

NP_001033022

Location (UCSC)Chr 20: 0.23 – 0.23 MbChr 2: 152.3 – 152.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Beta-defensin 129 is a protein that in humans is encoded by the DEFB129 gene.[5][6]

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125903Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074681Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved β-defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. Bibcode:2002PNAS...99.2129S. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.
  6. ^ a b "Entrez Gene: DEFB129 defensin, beta 129".

Further reading

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