From Wikipedia, the free encyclopedia
Protein-coding gene in humans
Cleavage stimulation factor 50 kDa subunit is a protein that in humans is encoded by the CSTF1 gene .[ 5] [ 6] [ 7]
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3' end cleavage of pre-mRNAs . Similar to mammalian G protein beta subunits , this protein contains transducin-like repeats . Several transcript variants with different 5' UTR , but encoding the same protein, have been found for this gene.[ 7]
CSTF1 has been shown to interact with BARD1 .[ 6] [ 8]
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