TFEC: Difference between revisions

TFEC
Identifiers
Aliases	TFEC, TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L, transcription factor EC
External IDs	OMIM: 604732; MGI: 1333760; HomoloGene: 32148; GeneCards: TFEC; OMA:TFEC - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	116,159,896 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	16,898,440 bp
RNA expression pattern
	Top expressed in
	monocyte; ; testicle; ; granulocyte; ; appendix; ; kidney tubule; ; bone marrow cells; ; spleen; ; lymph node; ; jejunal mucosa; ; upper lobe of left lung;
	Top expressed in
	epithelium of small intestine; ; migratory enteric neural crest cell; ; proximal tubule; ; stroma of bone marrow; ; right kidney; ; human kidney; ; yolk sac; ; morula; ; efferent ductule; ; granulocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription coactivator activity; protein binding; protein dimerization activity; transcription corepressor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm;
Biological process	cellular response to heat; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of nucleic acid-templated transcription; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	22797
	21426
	ENSG00000105967
	ENSMUSG00000029553
	O14948
	Q9WTW4
	NM_001018058; NM_001244583; NM_012252
	NM_031198
	NP_001018068; NP_001231512; NP_036384
	NP_112475
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 15:02, 11 June 2008

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Transcription factor EC, also known as TFEC, is a human gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105967 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029553 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: TFEC transcription factor EC".

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 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Zhao GQ, Zhao Q, Zhou X, ''et al.'' |title=TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4505-12 |year= 1993 |pmid= 8336698 |doi=  }}
+*{{cite journal  | author=Zhao GQ, Zhao Q, Zhou X, ''et al.'' |title=TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4505–12 |year= 1993 |pmid= 8336698 |doi=  }}
-*{{cite journal  | author=Yasumoto K, Shibahara S |title=Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator. |journal=Biochim. Biophys. Acta |volume=1353 |issue= 1 |pages= 23-31 |year= 1997 |pmid= 9256061 |doi=  }}
+*{{cite journal  | author=Yasumoto K, Shibahara S |title=Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator. |journal=Biochim. Biophys. Acta |volume=1353 |issue= 1 |pages= 23–31 |year= 1997 |pmid= 9256061 |doi=  }}
-*{{cite journal  | author=Steingrímsson E, Tessarollo L, Reid SW, ''et al.'' |title=The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. |journal=Development |volume=125 |issue= 23 |pages= 4607-16 |year= 1999 |pmid= 9806910 |doi=  }}
+*{{cite journal  | author=Steingrímsson E, Tessarollo L, Reid SW, ''et al.'' |title=The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. |journal=Development |volume=125 |issue= 23 |pages= 4607–16 |year= 1999 |pmid= 9806910 |doi=  }}
-*{{cite journal  | author=Chung MC, Kim HK, Kawamoto S |title=TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells. |journal=Biochemistry |volume=40 |issue= 30 |pages= 8887-97 |year= 2001 |pmid= 11467950 |doi=  }}
+*{{cite journal  | author=Chung MC, Kim HK, Kawamoto S |title=TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells. |journal=Biochemistry |volume=40 |issue= 30 |pages= 8887–97 |year= 2001 |pmid= 11467950 |doi=  }}
-*{{cite journal  | author=Mansky KC, Sulzbacher S, Purdom G, ''et al.'' |title=The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. |journal=J. Leukoc. Biol. |volume=71 |issue= 2 |pages= 304-10 |year= 2002 |pmid= 11818452 |doi=  }}
+*{{cite journal  | author=Mansky KC, Sulzbacher S, Purdom G, ''et al.'' |title=The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. |journal=J. Leukoc. Biol. |volume=71 |issue= 2 |pages= 304–10 |year= 2002 |pmid= 11818452 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
+*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
-*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
+*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
+*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
 }}
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Revision as of 15:02, 11 June 2008

References

Further reading