VTN

VTN
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1OC0, 1S4G, 1SSU, 2JQ8, 3BT1, 3BT2, 4K24
Dynodwyr
Cyfenwau	VTN, V75, VN, VNT, vitronectin
Dynodwyr allanol	OMIM: 193190 HomoloGene: 532 GeneCards: VTN
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • scavenger receptor activity; • heparin binding; • extracellular matrix binding; • polysaccharide binding; • integrin binding; • identical protein binding; • collagen binding; • extracellular matrix structural constituent;
Cydrannau o'r gell	• alphav-beta3 integrin-vitronectin complex; • extracellular exosome; • blood microparticle; • Golgi lumen; • basement membrane; • rough endoplasmic reticulum lumen; • cytoplasm; • GO:0005578 extracellular matrix; • extracellular space; • Reticwlwm endoplasmig; • intracellular membrane-bounded organelle; • extracellular region; • collagen-containing extracellular matrix;
Prosesau biolegol	• receptor-mediated endocytosis; • positive regulation of protein binding; • cell adhesion; • positive regulation of cell-substrate adhesion; • extracellular matrix organization; • smooth muscle cell-matrix adhesion; • regulation of complement activation; • positive regulation of smooth muscle cell migration; • negative regulation of endopeptidase activity; • positive regulation of peptidyl-tyrosine phosphorylation; • positive regulation of vascular endothelial growth factor receptor signaling pathway; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response; • endodermal cell differentiation; • positive regulation of wound healing; • positive regulation of receptor-mediated endocytosis; • negative regulation of blood coagulation; • oligodendrocyte differentiation; • cell adhesion mediated by integrin; • cell-matrix adhesion; • protein polymerization; • liver regeneration; • cell population proliferation; • cell migration; • vesicle-mediated transport; • endocytosis;
	Sources:Amigo / QuickGO
Orthologau
	7448
	n/a
	ENSG00000109072
	n/a
	P04004
	n/a
	NM_000638
	n/a
	NP_000629
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VTN yw VTN a elwir hefyd yn Vitronectin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q11.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VTN.

VN
V75
VNT

Llyfryddiaeth

"The Rickettsia conoriiAdr1 Interacts with the C-Terminus of Human Vitronectin in a Salt-Sensitive Manner. ". Front Cell Infect Microbiol. 2017. PMID 28299286.
"Diagnostic and prognostic value of serum vitronectin levels in human glioma. ". J Neurol Sci. 2016. PMID 27871448.
"Diagnostic and prognostic roles of serum vitronectin in hepatitis B-related hepatocellular carcinoma. ". Cancer Biomark. 2016. PMID 27802203.
"Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin. ". EMBO Rep. 2016. PMID 27189837.
"Vitronectin significantly influences prognosis in osteosarcoma.". Int J Clin Exp Pathol. 2015. PMID 26617861.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] VTN - Cronfa NCBI

[1]

[2]