LAMC1

LAMC1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1KLO, 1NPE, 1TLE, 4AQT
Dynodwyr
Cyfenwau	LAMC1, LAMB2, Laminin, gamma 1, laminin subunit gamma 1
Dynodwyr allanol	OMIM: 150290 HomoloGene: 1724 GeneCards: LAMC1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • extracellular matrix structural constituent • extracellular matrix constituent conferring elasticity Cydrannau o'r gell • GO:0005578 extracellular matrix • extracellular region • basement membrane • laminin-1 complex • extracellular exosome • laminin-10 complex • laminin-11 complex • extracellular space • endoplasmic reticulum lumen • collagen-containing extracellular matrix Prosesau biolegol • hemidesmosome assembly • substrate adhesion-dependent cell spreading • endoderm development • cell adhesion • extracellular matrix organization • cell migration • positive regulation of epithelial cell proliferation • extracellular matrix disassembly • post-translational protein modification • GO:0034622 protein-containing complex assembly • animal organ morphogenesis • tissue development • organism system development • basement membrane assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3915	n/a
Ensembl	ENSG00000135862	n/a
UniProt	P11047	n/a
RefSeq (mRNA)	NM_002293	n/a
RefSeq (protein)	NP_002284	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LAMC1 yw LAMC1 a elwir hefyd yn Laminin subunit gamma-1 a Laminin subunit gamma 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LAMC1.

• LAMB2

Llyfryddiaeth

• "A functional polymorphism located at transcription factor binding sites, rs6695837 near LAMC1 gene, confers risk of colorectal cancer in Chinese populations. ". Carcinogenesis. 2017. PMID 28039327.
• "Laminin C1 expression by uterine carcinoma cells is associated with tumor progression. ". Gynecol Oncol. 2015. PMID 26343160.
• "Anti-laminin-gamma 1 Pemphigoid with Generalized Pustular Psoriasis and Psoriasis Vulgaris. ". Acta Derm Venereol. 2016. PMID 26074471.
• "Anti-laminin-γ1 pemphigoid developed in a case of autosomal recessive congenital ichthyosis. ". Acta Derm Venereol. 2015. PMID 24733442.
• "Association between laminin γ1 expression and meningioma grade, recurrence, and progression-free survival.". Acta Neurochir (Wien). 2013. PMID 23053286.