KDM7A
Izgled
Lizin-demetilaza 7A je protein/enzim koji je kod ljudi kodiran genom KDM7A.[5]
Aminokiselinska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 941 aminokiselina, а molekulska težina 106.557 Da.[6]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MAGAAAAVAA | GAAAGAAAAA | VSVAAPGRAS | APPPPPPVYC | VCRQPYDVNR | ||||
FMIECDICKD | WFHGSCVGVE | EHHAVDIDLY | HCPNCAVLHG | SSLMKKRRNW | ||||
HRHDYTEIDD | GSKPVQAGTR | TFIKELRSRV | FPSADEIIIK | MHGSQLTQRY | ||||
LEKHGFDVPI | MVPKLDDLGL | RLPSPTFSVM | DVERYVGGDK | VIDVIDVARQ | ||||
ADSKMTLHNY | VKYFMNPNRP | KVLNVISLEF | SDTKMSELVE | VPDIAKKLSW | ||||
VENYWPDDSV | FPKPFVQKYC | LMGVQDSYTD | FHIDFGGTSV | WYHVLWGEKI | ||||
FYLIKPTDEN | LARYESWSSS | VTQSEVFFGD | KVDKCYKCVV | KQGHTLFVPT | ||||
GWIHAVLTSQ | DCMAFGGNFL | HNLNIGMQLR | CYEMEKRLKT | PDLFKFPFFE | ||||
AICWFVAKNL | LETLKELRED | GFQPQTYLVQ | GVKALHTALK | LWMKKELVSE | ||||
HAFEIPDNVR | PGHLIKELSK | VIRAIEEENG | KPVKSQGIPI | VCPVSRSSNE | ||||
ATSPYHSRRK | MRKLRDHNVR | TPSNLDILEL | HTREVLKRLE | MCPWEEDILS | ||||
SKLNGKFNKH | LQPSSTVPEW | RAKDNDLRLL | LTNGRIIKDE | RQPFADQSLY | ||||
TADSENEEDK | RRTKKAKMKI | EESSGVEGVE | HEESQKPLNG | FFTRVKSELR | ||||
SRSSGYSDIS | ESEDSGPECT | ALKSIFTTEE | SESSGDEKKQ | EITSNFKEES | ||||
NVMRNFLQKS | QKPSRSEIPI | KRECPTSTST | EEEAIQGMLS | MAGLHYSTCL | ||||
QRQIQSTDCS | GERNSLQDPS | SCHGSNHEVR | QLYRYDKPVE | CGYHVKTEDP | ||||
DLRTSSWIKQ | FDTSRFHPQD | LSRSQKCIRK | EGSSEISQRV | QSRNYVDSSG | ||||
SSLQNGKYMQ | NSNLTSGACQ | ISNGSLSPER | PVGETSFSVP | LHPTKRPASN | ||||
PPPISNQATK | GKRPKKGMAT | AKQRLGKILK | LNRNGHARFF | V |
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000006459 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042599 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Lysine demethylase 7A". Pristupljeno 9. 4. 2016.
- ^ "UniProt, Q6ZMT4" (jezik: engleski). Pristupljeno 25. 9. 2021.
Dopunska literatura
[uredi | uredi izvor]- Huang C, Xiang Y, Wang Y, Li X, Xu L, Zhu Z, Zhang T, Zhu Q, Zhang K, Jing N, Chen CD (2010). "Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4". Cell Res. 20 (2): 154–65. doi:10.1038/cr.2010.5. PMID 20084082.
Vanjski linkovi
[uredi | uredi izvor]- PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysine-specific demethylase 7A (KDM7A)