ECOP
Izgled
EGFR- koamplificirani i preeksprimirani protein, takođe poznat i kao COP, jest ljudski gen.[5]
Aminokiselinska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 172 aminokiseline, а molekulska težina 19.224 Da.[6]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MRRQPAKVAA | LLLGLLLECT | EAKKHCWYFE | GLYPTYYICR | SYEDCCGSRC | ||||
CVRALSIQRL | WYFWFLLMMG | VLFCCGAGFF | IRRRMYPPPL | IEEPAFNVSY | ||||
TRQPPNPGPG | AQQPGPPYYT | DPGGPGMNPV | GNSMAMAFQV | PPNSPQGSVA | ||||
CPPPPAYCNT | PPPPYEQVVK | AK |
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000154978 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037788 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: ECOP EGFR-coamplified and overexpressed protein".
- ^ "UniProt, Q96AW1" (jezik: engleski). Pristupljeno 24. 9. 2021.
Dopunska literatura
[uredi | uredi izvor]- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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- Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
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- Park S, James CD (2005). "ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner". Oncogene. 24 (15): 2495–502. doi:10.1038/sj.onc.1208496. PMID 15735698.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Brem H, Stojadinovic O, Diegelmann RF, et al. (2007). "Molecular Markers in Patients with Chronic Wounds to Guide Surgical Debridement". Mol. Med. 13 (1–2): 30–9. doi:10.2119/2006-00054.Brem. PMC 1869625. PMID 17515955.