DMTF1
Izgled
Ciklin-D-vezujući myboliki transkripcijski faktor 1 je protein koji je kod ljudi kodiran genom DMTF1.[5][6]
Aminokiselinska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 760 aminokiselina, а molekulska težina 84.471 Da.[7]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MSTVEEDSDT | VTVETVNSVT | LTQDTEGNLI | LHCPQNEADE | IDSEDSIEPP | ||||
HKRLCLSSED | DQSIDDSTPC | ISVVALPLSE | NDQSFEVTMT | ATTEVADDEV | ||||
TEGTVTQIQI | LQNEQLDEIS | PLGNEEVSAV | SQAWFTTKED | KDSLTNKGHK | ||||
WKQGMWSKEE | IDILMNNIER | YLKARGIKDA | TEIIFEMSKD | ERKDFYRTIA | ||||
WGLNRPLFAV | YRRVLRMYDD | RNHVGKYTPE | EIEKLKELRI | KHGNDWATIG | ||||
AALGRSASSV | KDRCRLMKDT | CNTGKWTEEE | EKRLAEVVHE | LTSTEPGDIV | ||||
TQGVSWAAVA | ERVGTRSEKQ | CRSKWLNYLN | WKQSGGTEWT | KEDEINLILR | ||||
IAELDVADEN | DINWDLLAEG | WSSVRSPQWL | RSKWWTIKRQ | IANHKDVSFP | ||||
VLIKGLKQLH | ENQKNNPTLL | ENKSGSGVPN | SNTNSSVQHV | QIRVARLEDN | ||||
TAISSSPMAA | LQIPVQITHV | SSADSPATVD | SETITLNSGT | LQTFEILPSF | ||||
HLQPTGTPGT | YLLQTSSSQG | LPLTLTASPT | VTLTAAAPAS | PEQIIVHALS | ||||
PEHLLNTSDN | VTVQCHTPRV | IIQTVATEDI | TSSISQAELT | VDSDIQSSDF | ||||
PEPPDALEAD | TFPDEIHHPK | MTVEPSFNDA | HVSKFSDQNS | TELMNSVMVR | ||||
TEEEISDTDL | KQEESPSDLA | SAYVTEGLES | PTIEEQVDQT | IDDETILIVP | ||||
SPHGFIQASD | VIDTESVLPL | TTLTDPILQH | HQEESNIIGS | SLGSPVSEDS | ||||
KDVEDLVNCH |
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000135164 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042508 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT (maj 1999). "Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)". Gene. 229 (1–2): 223–8. doi:10.1016/S0378-1119(98)00591-5. PMID 10095122.
- ^ "Entrez Gene: DMTF1 cyclin D binding myb-like transcription factor 1".
- ^ "UniProt, Q9Y222" (jezik: engleski). Pristupljeno 24. 9. 2021.
Dopunska literatura
[uredi | uredi izvor]- Försti A, Angelini S, Festa F, et al. (2004). "Single nucleotide polymorphisms in breast cancer". Oncol. Rep. 11 (4): 917–22. doi:10.3892/or.11.4.917. PMID 15010895.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Tschan MP, Fischer KM, Fung VS, et al. (2003). "Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns". J. Biol. Chem. 278 (44): 42750–60. doi:10.1074/jbc.M307067200. PMID 12917399.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- <Please add first missing authors to populate metadata.> (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Inoue K, Sherr CJ, Shapiro LH (1998). "Regulation of the CD13/aminopeptidase N gene by DMP1, a transcription factor antagonized by D-type cyclins". J. Biol. Chem. 273 (44): 29188–94. doi:10.1074/jbc.273.44.29188. PMID 9786929.
- Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
- Hirai H, Sherr CJ (1996). "Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1". Mol. Cell. Biol. 16 (11): 6457–67. doi:10.1128/MCB.16.11.6457. PMC 231647. PMID 8887674.
- Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.