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DMTF1

S Wikipedije, slobodne enciklopedije
DMTF1
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

2LLK

Identifikatori
AliasiDMTF1
Vanjski ID-jeviOMIM: 608491 MGI: 1344415 HomoloGene: 8017 GeneCards: DMTF1
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za DMTF1
Genomska lokacija za DMTF1
Bend7q21.12Početak87,152,361 bp[1]
Kraj87,196,337 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za DMTF1
Genomska lokacija za DMTF1
Bend5|5 A1Početak9,168,801 bp[2]
Kraj9,211,776 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
vezivanje sa DNK
sequence-specific DNA binding
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
Ćelijska komponenta nukleoplazma
citosol
jedro
Biološki proces ćelijski ciklus
GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Ćelijska diferencijacija
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001142326
NM_001142327
NM_021145

NM_001110327
NM_011806

RefSeq (bjelančevina)

NP_001135798
NP_001135799
NP_066968

NP_001103797
NP_035936

Lokacija (UCSC)Chr 7: 87.15 – 87.2 MbChr 5: 9.17 – 9.21 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Ciklin-D-vezujući myboliki transkripcijski faktor 1 je protein koji je kod ljudi kodiran genom DMTF1.[5][6]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 760 aminokiselina, а molekulska težina 84.471 Da.[7]

1020304050
MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNEADEIDSEDSIEPP
HKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEV
TEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHK
WKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIA
WGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIG
AALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIV
TQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILR
IAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFP
VLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLEDN
TAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSF
HLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALS
PEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDF
PEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVR
TEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVP
SPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDS
KDVEDLVNCH

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135164 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042508 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT (maj 1999). "Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)". Gene. 229 (1–2): 223–8. doi:10.1016/S0378-1119(98)00591-5. PMID 10095122.
  6. ^ "Entrez Gene: DMTF1 cyclin D binding myb-like transcription factor 1".
  7. ^ "UniProt, Q9Y222" (jezik: engleski). Pristupljeno 24. 9. 2021.

Dopunska literatura

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