WormBook is a comprehensive, open-access collection of original,
peer-reviewed chapters covering topics related to the biology of Caenorhabditis
elegans and other nematodes. Wormbook also contains: WormMethods, a collection of
protocols for nematode researchers; WormHistory, personal perspectives on C. elegans
research; and the Worm Breeder's Gazette, an informal, non-refereed, biannual
newsletter for the interchange of ideas and information related to C. elegans and
other nematodes. Additional chapters can be found in GENETICS.
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News and Notes
May 2, 2018
New chapter added to Genetics and genomics
Caenorhabditis nomenclature, by Mary Ann Tuli, Aric Daul, and Tim Schedl, has been added to the Genetics and genomics section of WormBook. This chapter details the nomenclature rules for C. elegans and other nematodes including the naming of transgenic and engineered variations.
January 30, 2018
Tubulin chapter added to WormBook
Tubulins in C. elegans, by Daryl Hurd, has just been pre-published ahead of formal publication in the Cell Biology section. This chapter describes the large family of tubulins in C. elegans, their cellular and developmental roles, biogenesis, and post-translational modifications.
March 23 2017
History Chapter added to WormBook
History of research on C. elegans and other free-living nematodes as model organisms, by Victor Marc Nigon and Marie-Anne Félix, has been added to the History section of Wormbook as a pre-publication. This chapter reviews the early history of using free-living nematodes as models to address general questions in biology. It focuses on the period beginning in 1899 with the first publication of Emile Maupas mentioning Rhabditis elegans and ending in 1974 with the first publications by Sydney Brenner.
August 23 2016
New chapter added to Cell Biology
Development, structure, and maintenance of C. elegans body wall muscle, by Kathrin Gieseler, Hiroshi Qadota, and Guy Benian, has been pre-published in the Cell Biology section. This chapter partially updates and greatly expands on Sarcomere assembly in C. elegans muscle by Don Moerman and Ben Williams. The new chapter includes detailed descriptions of sarcomere components, their assembly, organization, regulation, and function. It also includes a discussion of insights into dystrophin function from C. elegans studies.
July 14 2016
New chapter added to WormMethods
Working with dauer larvae, by Xantha Karp, has been added to the Behavior section of WormMethods as an ePub ahead of formal publication. This chapter summarizes dauer formation and describes methods for inducing and isolating dauers. Methods for obtaining pre- and post-dauer larvae are also provided.
May 24 2016
Small GTPase chapter updated
Small GTPases (2016), by David Reiner and Erik Lundquist, has been added to the Signal transduction section. This chapter updates the 2006 chapter by Lundquist with the same title. The new chapter provides an overview of small GTPases in C. elegans and gives details for members of the Ras, Rho, Rab, Arf, and Ran families. Atypical nematode members that fall outside these subfamilies are also discussed.
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