Butirosin

Butirosin
INN: Butirosin
	Butirosin A (top) and butirosin B (bottom)
Clinical data
Other names	Ambutyrosin; Butyrosin
Drug class	Aminoglycoside antibiotic
Identifiers
CAS Number	12772-35-9 ;
PubChem CID	72393;
ChemSpider	65326;
UNII	8S52KR0L58;
KEGG	C01559;
ChEBI	CHEBI:65109;
CompTox Dashboard (EPA)	DTXSID60925967 ;
Chemical and physical data
3D model (JSmol)	Interactive image;
	SMILES C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N;
	InChI InChI=1S/C21H41N5O12/c22-2-1-8(28)19(34)26-7-3-6(24)17(37-20-11(25)15(32)13(30)9(4-23)35-20)18(12(7)29)38-21-16(33)14(31)10(5-27)36-21/h6-18,20-21,27-33H,1-5,22-25H2,(H,26,34)/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15+,16+,17+,18+,20+,21+/m0/s1; Key:XEQLFNPSYWZPOW-NUOYRARPSA-N;

Butirosin is an aminoglycoside antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.^[1] It is a mixture with butirosin A (80-85%) and butirosin B being the major components.^[2]

References

^ Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.
^ Elks J (2014). The Dictionary of Drugs. Springer. p. 198.

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