Clostridioides is a genus of Gram-positive bacteria, which includes Clostridioides difficile, a human pathogen causing an infectious diarrhea.
| Clostridioides | |
|---|---|
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| SE micrograph of Clostridioides difficile colonies from a stool sample | |
Scientific classification 
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| Domain: | Bacteria |
| Phylum: | Bacillota |
| Class: | Clostridia |
| Order: | Eubacteriales |
| Family: | Peptostreptococcaceae |
| Genus: | Clostridioides Lawson and Rainey (2016) |
| Selected species | |
Taxonomy
editThe genus Clostridioides was created to describe a few species formerly in the genus Clostridium which have been shown to be their own genetically distinct genus using 16S rRNA gene sequencing analysis.[1] However, both names are still in use and valid under the International Code of Nomenclature of Prokaryotes.[2] Since C. mangenotii was further separated into a distinct genus in 2024,[3] Clostridioides is a monotypic genus.
Description
editThey are obligate anaerobes capable of producing endospores. The normal, reproducing cells of Clostridioides, called the vegetative form, are rod-shaped, which gives them their name, from the Greek κλωστήρ or spindle. Clostridioides endospores, like Clostridium endospores, have a distinct bowling pin or bottle shape, distinguishing them from other bacterial endospores, which are usually ovoid in shape.[citation needed]
References
edit- ^ Lawson, Paul A.; Citron, Diane M.; Tyrrell, Kerin L.; Finegold, Sydney M. (August 2016). "Reclassification of Clostridium difficile as Clostridioides difficile (Hall and O'Toole 1935) Prévot 1938". Anaerobe. 40: 95–99. doi:10.1016/j.anaerobe.2016.06.008. PMID 27370902.
- ^ Oren, Aharon; Rupnik, Maja (August 2018). "Clostridium difficile and Clostridioides difficile: Two validly published and correct names". Anaerobe. 52: 125–126. doi:10.1016/j.anaerobe.2018.07.005. PMID 30031828. S2CID 51707574.
- ^ Bello, Sarah; McQuay, Sarah; Rudra, Bashudev; Gupta, Radhey (2024). "Robust demarcation of the family Peptostreptococcaceae and its main genera based on phylogenomic studies and taxon-specific molecular markers". International Journal of Systematic and Evolutionary Microbiology. 74 (2). doi:10.1099/ijsem.0.006247. PMID 38319314.