1cP-LSD (N1-(cyclopropylmethanoyl)-lysergic acid diethylamide) is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug. [1][2] It was first synthesized as a legal-LSD alternative by Lizard Labs, a Netherlands based research chemical laboratory.[3] In tests on mice it was found to be an active psychedelic with similar potency to 1P-LSD.[4]

1cP-LSD
Clinical data
Other names1cP, acid, LSD, Lucy
Dependence
liability
Low
Addiction
liability
None
Routes of
administration
By mouth, under the tongue
Legal status
Legal status
Pharmacokinetic data
Onset of action30 - 60 minutes
Duration of action8 - 24 hours
Identifiers
  • (6aR,9R)-N,N-diethyl-7-methyl-4-cyclopropylmethanoyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC24H29N3O2
Molar mass391.515 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C@@H]5C=C2[C@@H](Cc3cn(C(=O)C1CC1)c4cccc2c34)N(C)C5
  • InChI=1S/C24H29N3O2/c1-4-26(5-2)23(28)17-11-19-18-7-6-8-20-22(18)16(12-21(19)25(3)13-17)14-27(20)24(29)15-9-10-15/h6-8,11,14-15,17,21H,4-5,9-10,12-13H2,1-3H3/t17-,21-/m1/s1
  • Key:RAFUPYYDHPFASC-DYESRHJHSA-N
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1cP-LSD on blotter paper

Sweden's public health agency suggested classifying 1cP-LSD as a dangerous substance on 18 December 2019 and later classified it as such on 22 April 2021.[5][6]

See also

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References

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  1. ^ Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2020). "[Identification of LSD Derivatives, 1cP-LSD, MIPLA and 1B-LSD in Illegal Products as Paper Sheet]". Yakugaku Zasshi. 140 (11): 1405–1413. doi:10.1248/yakushi.20-00124. PMID 33132277.
  2. ^ Vincenti F, Gregori A, Flammini M, Di Rosa F, Salomone A (July 2021). "Seizures of New Psychoactive Substances on the Italian territory during the COVID-19 pandemic". Forensic Science International. 326: 110904. doi:10.1016/j.forsciint.2021.110904. PMC 8411784. PMID 34371393.
  3. ^ spotlight (2018-07-25). "About Us - Lizard Labs". lizardlabs.nl. Retrieved 2024-09-13.
  4. ^ Brandt SD, Kavanagh PV, Westphal F, Stratford A, Odland AU, Klein AK, et al. (June 2020). "Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)". Drug Testing and Analysis. 12 (6): 812–826. doi:10.1002/dta.2789. PMC 9191646. PMID 32180350.
  5. ^ "Förordning (1999:58) om förbud mot vissa hälsofarliga varor".
  6. ^ "Tjugotre ämnen föreslås klassas som narkotika eller hälsofarlig vara" [Twenty-three substances are proposed to be classified as drugs or dangerous goods] (in Swedish). Folkhälsomyndigheten. December 18, 2019. Archived from the original on November 24, 2022. Retrieved May 28, 2020.