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integrin subunit beta 1 (Q4201966)

From Wikidata
mammalian protein found in Homo sapiens
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
  • GPIIA
  • very late activation protein, beta polypeptide
  • Fibronectin receptor subunit beta
  • integrin VLA-4 beta subunit
  • integrin beta-1
  • ITGB1
  • integrin beta 1
  • VLA-4 subunit beta
  • glycoprotein IIa
  • Integrin beta1
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    English
    integrin subunit beta 1
    mammalian protein found in Homo sapiens
    • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
    • GPIIA
    • very late activation protein, beta polypeptide
    • Fibronectin receptor subunit beta
    • integrin VLA-4 beta subunit
    • integrin beta-1
    • ITGB1
    • integrin beta 1
    • VLA-4 subunit beta
    • glycoprotein IIa
    • Integrin beta1

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    43 references
    retrieved
    8 April 2019
    stated in
    Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel intracellular fibulin-1D variant binds to the cytoplasmic domain of integrin beta 1 subunit
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NAG-2, a Novel Transmembrane-4 Superfamily (TM4SF) Protein That Complexes with Integrins and Other TM4SF Proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Effect of medium change on the development of in vitro matured and fertilized bovine oocytes cultured in medium containing amino acids
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ICAP-1, a Novel β1 Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β1 Integrin
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Basic amino-acid side chains regulate transmembrane integrin signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structure of three tandem filamin domains reveals auto-inhibition of ligand binding
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Filamin A regulates cell spreading and survival via beta1 integrins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Thrombospondin-1 acts via IAP/CD47 to synergize with collagen in alpha2beta1-mediated platelet activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SHARPIN is an endogenous inhibitor of β1-integrin activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ganglioside GM3 Inhibits Matrix Metalloproteinase-9 Activation and Disrupts Its Association with Integrin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A family of beta 7 integrins on human mucosal lymphocytes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural Diversity in Integrin/Talin Interactions
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Role of dystrophins and utrophins in platelet adhesion process
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Characterization of L‐plastin interaction with beta integrin and its regulation by micro‐calpain
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IPI
    cell component
    cell surface
    determination method or standard
    IDA
    IEA
    17 references
    retrieved
    26 September 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    26 September 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    26 September 2017
    stated in
    Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Characterization of integrin engagement during defined human embryonic stem cell culture
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Platelet Proteome Analysis Reveals Integrin-dependent Aggregation Defects in Patients with Myelodysplastic Syndromes
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Quantitative proteomics identifies a Dab2/integrin module regulating cell migration
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor β
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    The Androgen Receptor Induces Integrin α6β1 to Promote Prostate Tumor Cell Survival via NF-κB and Bcl-xL Independently of PI3K Signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    plasma membrane
    determination method or standard
    NAS
    IDA
    TAS
    IEA
    7 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    A novel protease-docking function of integrin at invadopodia
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    NAS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The Androgen Receptor Induces Integrin α6β1 to Promote Prostate Tumor Cell Survival via NF-κB and Bcl-xL Independently of PI3K Signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Role of dystrophins and utrophins in platelet adhesion process
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    focal adhesion
    determination method or standard
    IDA
    IEA
    6 references
    retrieved
    26 September 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    26 September 2017
    stated in
    Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    26 September 2017
    stated in
    Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    focal adhesion
    determination method or standard
    HDA
    IBA
    IDA
    IEA
    8 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IBA
    retrieved
    8 April 2019
    stated in
    Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    HDA
    cell surface
    determination method or standard
    HDA
    IBA
    IDA
    IEA
    18 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor β
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Characterization of integrin engagement during defined human embryonic stem cell culture
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The Androgen Receptor Induces Integrin α6β1 to Promote Prostate Tumor Cell Survival via NF-κB and Bcl-xL Independently of PI3K Signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IBA
    retrieved
    8 April 2019
    stated in
    Platelet Proteome Analysis Reveals Integrin-dependent Aggregation Defects in Patients with Myelodysplastic Syndromes
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    HDA
    retrieved
    8 April 2019
    stated in
    Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    HDA
    retrieved
    8 April 2019
    stated in
    Quantitative proteomics identifies a Dab2/integrin module regulating cell migration
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    HDA
    retrieved
    8 April 2019
    stated in
    Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    HDA
    biological process
    cell-matrix adhesion
    determination method or standard
    IEA
    IMP
    5 references
    retrieved
    26 September 2017
    stated in
    CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    26 September 2017
    stated in
    Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    26 September 2017
    stated in
    Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    26 September 2017
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    26 September 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P05556&geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    cell-matrix adhesion
    determination method or standard
    IBA
    IEA
    IMP
    6 references
    retrieved
    8 April 2019
    stated in
    CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner
    GOA
    curator
    UniProt
    UniProt protein ID
    P05556
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05556
    determination method or standard
    IBA

    Identifiers

    MeSH descriptor ID
    D019012
    subject named as
    Integrin beta1
    0 references
    Freebase ID
    /m/02q6c22
    0 references
     
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q4201966&oldid=2022905186"