ribociclib (Q27088552)

LEE011 (English)

19 October 2016

C₂₃H₃₀N₈O

1 reference

LEE011 (English)

19 October 2016

CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5

1 reference

World Health Organisation international non-proprietary name

LEE011 (English)

19 October 2016

1 reference

14 February 2018

ribociclib (English)

1 reference

published in

Recommended INN: List 73

publication date

2015

medical condition treated

breast cancer

0 references

physically interacts with

Cyclin dependent kinase 6

subject has role

reaction inhibitor

1 reference

Open Targets Platform

https://platform.opentargets.org/drug/CHEMBL3545110

14 August 2023

reference URL

LiverTox likelihood score

LiverTox toxicity likelihood category C

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Ribociclib

last update

8 May 2018

subject has role

protein kinase inhibitors

0 references

NCI Thesaurus ID

C95701

1 reference

InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)

14 February 2018

Ribociclib

0 references

Identifiers

InChI

1 reference

LEE011 (English)

19 October 2016

2 references

LEE011 (English)

19 October 2016

14 February 2018

2 references

14 February 2018

https://commonchemistry.cas.org/detail?cas_rn=1211441-98-3

9 April 2021

1 reference

ribociclib (English)

19 October 2016

2 references

English

title

LEE011 (English)

19 October 2016

ChEBI ID

230905

mapping relation type

exact match

1 reference

International Chemical Identifier

InChI

InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)

1 reference

Ribociclib (English)

19 October 2016

2 references

inferred from InChIKey

1 reference

1 reference

ECHA Substance Infocard database

0 references

1 reference

ECHA Substance Infocard ID

100.234.566

ECHA Substance Infocard ID

29 July 2019

title

7-Cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide (English)

quotation

CAS no.: 1211441-98-3 (English)

100.234.566

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.234.566

World Health Organisation international non-proprietary name numeric ID

29 July 2019

title

7-Cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide (English)

quotation

CAS no.: 1211441-98-3 (English)

ATC code

L01XE42

0 references

9968

1 reference

reference URL

https://mednet-communities.net/inn/db/ViewINN.aspx?i=9968

Guide to Pharmacology Ligand ID

7383

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7383

ribociclib (English)

19 October 2016

1 reference

14 February 2018

1 reference

Human Metabolome Database ID

HMDB0257211

2 references

based on heuristic

inferred from InChIKey

UNII

TK8ERE8P56

2 references

UNII

TK8ERE8P56

14 February 2018

MedlinePlus drug identifier

a617008

0 references

PatientsLikeMe treatment ID

0 references

1 reference

26 February 2018

0 references

1 reference

0 references

0 references

Google Knowledge Graph ID

/g/11c2y30327

0 references

Microsoft Academic ID

0 references

1 reference