G protein-coupled estrogen receptor 1 (Q5514257)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99527

G protein-coupled receptor

1 reference

Transporter Classification Database ID

9.A.14.13.19

hierarchical database ID heuristic

2 October 2019

based on heuristic

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

estrogen receptor activity

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

steroid hormone binding

1 reference

8 April 2019

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

chromatin binding

1 reference

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

protein binding

3 references

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

1 reference

1 January 2018

G protein-coupled receptor activity

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

G protein-coupled receptor activity

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

estrogen receptor activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

steroid hormone receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

cell component

cytoplasm

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

nuclear envelope

1 reference

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

trans-Golgi network

1 reference

8 April 2019

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

mitochondrion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

3 references

8 April 2019

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

keratin filament

1 reference

8 April 2019

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

dendritic shaft

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

dendritic spine head

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

3 references

8 April 2019

8 April 2019

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

dendritic spine membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 references

8 April 2019

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

presynaptic active zone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

axon terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

Golgi membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

integral component of plasma membrane

1 reference

8 April 2019

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

presynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

hippocampal mossy fiber to CA3 synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

3 references

8 April 2019

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

1 reference

7 November 2018

positive regulation of protein phosphorylation

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of ERK1 and ERK2 cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of extrinsic apoptotic signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

negative regulation of inflammatory response

1 reference

8 April 2019

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

steroid hormone mediated signaling pathway

1 reference

8 April 2019

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

negative regulation of cell population proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

negative regulation of leukocyte activation

1 reference

8 April 2019

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

apoptotic chromosome condensation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

regulation of cytosolic calcium ion concentration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of neurotransmitter secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

nuclear fragmentation involved in apoptotic nuclear change

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of endothelial cell apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of inositol trisphosphate biosynthetic process

1 reference

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of cardiac vascular smooth muscle cell differentiation

1 reference

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

5 references

8 April 2019

8 April 2019

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

negative regulation of protein kinase B signaling

1 reference

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

negative regulation of cell cycle process

1 reference

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of release of sequestered calcium ion into cytosol

1 reference

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of release of cytochrome c from mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of cell migration

1 reference

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cellular response to tumor necrosis factor

1 reference

8 April 2019

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cellular response to estradiol stimulus

9 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

16 July 2018

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

cellular response to peptide hormone stimulus

1 reference

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

cellular response to mineralocorticoid stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of cell population proliferation

1 reference

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

negative regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

negative regulation of DNA metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

positive regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of uterine smooth muscle contraction

1 reference

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

neuronal action potential

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

mineralocorticoid receptor signaling pathway

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

positive regulation of apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

1 reference

8 April 2019

intracellular steroid hormone receptor signaling pathway

1 reference

16 July 2018

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

positive regulation of protein localization to plasma membrane

1 reference

8 April 2019

G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

adenylate cyclase-activating G protein-coupled receptor signaling pathway

1 reference

1 January 2018

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99527&geneProductId=UniProtKB:Q99527

modulation of chemical synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

intracellular steroid hormone receptor signaling pathway

cellular response to estradiol stimulus

10 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99527

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1013

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1016

language of work or name

English

http://purl.uniprot.org/uniprot/Q99527

17 August 2016

Gene Atlas image

PBB GE GPR30 210640 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

GPCR, rhodopsin-like, 7TM

Identifiers.org

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99527

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

Transporter Classification Database ID

9.A.14.13.19

2 references

Transporter Classification database

13 March 2020

Transporter Classification database