amphotericin B (Q412223)

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chemical compound

APT370
AMPH-b
C-AmB
liposomal amphotericin B

Language	Label	Description	Also known as
English	amphotericin B	chemical compound	APT370 AMPH-b C-AmB liposomal amphotericin B

Statements

type of chemical entity

0 references

0 references

APKFDSVGJQXUKY-ZCGADPMASA-N

1 reference

based on heuristic

inferred from SMILES

1 reference

Amphotericin B (English)

language of work or name

publication date

17 November 2015

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

chemical structure

Amphotericin B new.svg
512 × 259; 19 KB

0 references

image of molecular model or crystal lattice model

Amphotericin b.png
890 × 664; 52 KB

space-filling model

0 references

923.488 dalton

1 reference

language of work or name

amphotericin b (English)

17 November 2016

stereoisomer of

2 references

based on heuristic

inferred from InChIKey

based on heuristic

inferred from InChI

2 references

based on heuristic

inferred from InChIKey

based on heuristic

inferred from InChI

2 references

based on heuristic

inferred from InChIKey

based on heuristic

inferred from InChI

chemical formula

C₄₇H₇₃NO₁₇

1 reference

language of work or name

amphotericin b (English)

17 November 2016

canonical SMILES

CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O

1 reference

language of work or name

amphotericin b (English)

17 November 2016

isomeric SMILES

C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O

1 reference

language of work or name

amphotericin b (English)

17 November 2016

defined daily dose

35 milligram

route of administration

parenteral route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=J02AA01

0.2 gram

route of administration

intravaginal administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=G01AA03

40 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=A01AB04

0.4 gram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=A07AA07

World Health Organisation international non-proprietary name

amphotericin B (English)

2 references

language of work or name

amphotericin B (English)

4 October 2016

Recommended INN: List 4

publication date

1962

Streptomyces hygroscopicus

1 reference

Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain

Ralstonia solanacearum

1 reference

Ralfuranone Is Produced by an Alternative Aryl-Substituted γ-Lactone Biosynthetic Route in Ralstonia solanacearum

Floricola striata

1 reference

p-Terphenyl Derivatives from the Endolichenic Fungus Floricola striata

Mirabilis jalapa

1 reference

Three new phenolic compounds from a manipulated plant cell culture, Mirabilis jalapa

Streptomyces albolongus

1 reference

Bafilomycins and Odoriferous Sesquiterpenoids from Streptomyces albolongus Isolated from Elephas maximus Feces

Trichoderma brevicompactum

1 reference

Trichothecenes from a Soil-Derived Trichoderma brevicompactum

1 reference

Terpenoids from Toona ciliata.

Colletotrichum higginsianum

1 reference

Deleting a Chromatin Remodeling Gene Increases the Diversity of Secondary Metabolites Produced by Colletotrichum higginsianum

Casearia sylvestris

1 reference

Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris

Penicillium convolutum

1 reference

Antifungal substances against pathogenic fungi, talaroconvolutins, from talaromyces convolutus

Talaromyces convolutus

1 reference

Antifungal substances against pathogenic fungi, talaroconvolutins, from talaromyces convolutus

Aspergillus wentii

1 reference

Aspewentins D-H, 20-Nor-isopimarane Derivatives from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310.

Streptomyces noursei

1 reference

Noursamycins, Chlorinated Cyclohexapeptides Identified from Molecular Networking of Streptomyces noursei NTR-SR4

Streptomyces violascens

1 reference

Violapyrones A-G, α-pyrone derivatives from Streptomyces violascens isolated from Hylobates hoolock feces

Trichoderma virens

1 reference

Trichocadinins B-G: Antimicrobial Cadinane Sesquiterpenes from Trichoderma virens QA-8, an Endophytic Fungus Obtained from the Medicinal Plant Artemisia argyi

Podospora australis

1 reference

Emestrins: Anti-Cryptococcus Epipolythiodioxopiperazines from Podospora australis.

Ascochyta medicaginicola

1 reference

Xanthepinone, an antimicrobial polyketide from a soil fungus closely related to Phoma medicaginis.

Artemisia argyi

1 reference

Trichocadinins B-G: Antimicrobial Cadinane Sesquiterpenes from Trichoderma virens QA-8, an Endophytic Fungus Obtained from the Medicinal Plant Artemisia argyi

Penicillium chermesinum

1 reference

Chermesins A-D: Meroterpenoids with a Drimane-Type Spirosesquiterpene Skeleton from the Marine Algal-Derived Endophytic Fungus Penicillium chermesinum EN-480.

2 references

Medermycin-Type Naphthoquinones from the Marine-Derived Streptomyces sp. XMA39

Bioactive Streptoglutarimides A-J from the Marine-Derived Streptomyces sp. ZZ741

1 reference

Wortmannin and Wortmannine Analogues from an Undescribed Niesslia sp

1 reference

Phthalide and Isocoumarin Derivatives Produced by an Acremonium sp. Isolated from a Mangrove Rhizophora apiculata

1 reference

Antimicrobial Furancarboxylic Acids from a Penicillium sp

Nocardia abscessus

1 reference

Nabscessins A and B, Aminocyclitol Derivatives from Nocardia abscessus IFM 10029T.

medical condition treated

coccidioidomycosis

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

fungal meningitis

1 reference

language of work or name

13 December 2016

chronic mucocutaneous candidiasis

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

visceral leishmaniasis

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

paracoccidioidomycosis

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

fungal infectious disease

1 reference

language of work or name

13 December 2016

urinary tract infection

1 reference

language of work or name

13 December 2016

entomophthoramycosis

1 reference

language of work or name

13 December 2016

cutaneous candidiasis

1 reference

language of work or name

13 December 2016

pregnancy category

US pregnancy category B

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category C

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/AmphotericinB

8 April 2016

subject has role

enzyme inhibitor

1 reference

5 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

essential medicine

0 references

1 reference

Identifiers

InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

1 reference

APKFDSVGJQXUKY-INPOYWNPSA-N

2 references

language of work or name

amphotericin b (English)

17 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

APKFDSVGJQXUKY-INPOYWNPSA-N

CAS Common Chemistry

9 April 2021

https://commonchemistry.cas.org/detail?cas_rn=1397-89-3

1 reference

language of work or name

Amphotericin B (English)

17 November 2016

1 reference

language of work or name

amphotericin b (English)

17 November 2016

Reaxys registry number

4645978

1 reference

language of work or name

amphotericin B (English)

4 October 2016

mapping relation type

1 reference

language of work or name

AMPHOTERICIN B (English)

17 November 2016

1 reference

language of work or name

AMPHOTERICIN B (English)

17 November 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

APKFDSVGJQXUKY-INPOYWNPSA-N

UniChem compound ID

1 reference

splash10-0a4i-1123235419-f891317fdaca7d831615

0 references

splash10-0006-0498435600-321adc31acae1790ffde

0 references

splash10-01ox-0389436800-eb8da79d46c3d954f0ab

0 references

splash10-01r6-0389435700-7986c789c46d4b5499a2

0 references

splash10-0006-0389436800-e3f5c5734c1d91848f93

0 references

splash10-009b-0496327200-ad27b8415f7c27b3eac7

0 references

CAMEO Chemicals ID

0 references

0 references

1 reference

Hazardous Substances Data Bank

publication date

28 October 2019

AMPHOTERICIN B (English)

10 May 2021

DSSTox substance ID

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

APKFDSVGJQXUKY-INPOYWNPSA-N

DSSTOX compound identifier

0 references

0 references

0 references

0 references

1 reference

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Amphotericin B (English)

CAS no.: 1397-89-3 (English)

1 reference

language of work or name

Amphotericin B (English)

publication date

17 November 2015

1 reference

language of work or name

Amphotericin B (English)

publication date

17 November 2015

1 reference

language of work or name

Amphotericin B (English)

publication date

17 November 2015

1 reference

language of work or name

Amphotericin B (English)

publication date

17 November 2015

World Health Organisation international non-proprietary name numeric ID

1 reference

https://mednet-communities.net/inn/db/ViewINN.aspx?i=869

MeSH descriptor ID

subject named as

Amphotericin B

0 references

MeSH concept ID

0 references

D02.540.576.500.500

0 references

1 reference

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

1 reference

matched by identifier from

APKFDSVGJQXUKY-INPOYWNPSA-N

Human Metabolome Database ID

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

APKFDSVGJQXUKY-INPOYWNPSA-N

2 references

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

matched by identifier from

APKFDSVGJQXUKY-INPOYWNPSA-N

PatientsLikeMe treatment ID

0 references

NIAID ChemDB ID

1 reference

imported from Wikimedia project

English Wikipedia

1 reference

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

Probes And Drugs ID

0 references

1 reference

1 reference

language of work or name

amphotericin B (English)

4 October 2016

1 reference

language of work or name

amphotericin B (English)

4 October 2016

0 references

0 references

electronic Essential Medicines List medicine ID

0 references

Encyclopædia Britannica Online ID

science/amphotericin-B

subject named as

amphotericin B

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

0 references

NCI Drug Dictionary ID

liposomal-amphotericin-b

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

ScienceDirect topic ID

agricultural-and-biological-sciences/amphotericin-b

0 references

UK Parliament thesaurus ID

subject named as

Amphotericin B

0 references

1 reference

Global Substance Registration System

language of work or name

amphotericin b (English)

17 November 2016

0 references

WikiProjectMed ID

0 references

Sitelinks

Wikipedia(34 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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