fluconazole (Q411478)

cargo

1 reference

Gene Ontology release 2019-11-16

fluconazole transport

cargo

1 reference

Gene Ontology release 2019-11-16

fluconazole:proton antiporter activity

cargo

1 reference

Gene Ontology release 2020-05-02

has use

medication

1 reference

Fluconazole (English)

DrugBank

17 November 2015

Fluconazole structure.svg
568 × 800; 3 KB

1 reference

image of molecular model or crystal lattice model

German Wikipedia

Fluconazole-from-xtal-3D-balls.png
1,004 × 1,100; 211 KB

depicts

ball-and-stick model

0 references

mass

306.104 dalton

1 reference

fluconazole (English)

19 October 2016

306.104065444 dalton

1 reference

inferred from InChI

chemical formula

C₁₃H₁₂F₂N₆O

1 reference

fluconazole (English)

19 November 2016

canonical SMILES

C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O

1 reference

World Health Organisation international non-proprietary name

fluconazole (English)

19 November 2016

1 reference

14 February 2018

fluconazole (English)

1 reference

In vitro and in vivo antifungal activities of the eight steroid saponins from Tribulus terrestris L. with potent activity against fluconazole-resistant fungal pathogens.

fluconazole (English)

19 October 2016

1 reference

Pseudallescheria boydii

1 reference

Antifungal agents from Pseudallescheria boydii SNB-CN73 isolated from a Nasutitermes sp. termite

Mirabilis jalapa

1 reference

Three new phenolic compounds from a manipulated plant cell culture, Mirabilis jalapa

Cordyceps farinosa

1 reference

Paecilosetin Derivatives as Potent Antimicrobial Agents from Isaria farinosa

Ganoderma gibbosum

1 reference

Triterpenoids from Ganoderma gibbosum: A Class of Sensitizers of FLC-Resistant Candida albicans to Fluconazole

Stachybotrys chartarum

1 reference

Antimicrobial Dolabellanes and Atranones from a Marine-Derived Strain of the Toxigenic Fungus Stachybotrys chartarum

Dendrodochium

1 reference

Polyhydroxy Cyclohexanols from a Dendrodochium sp. Fungus Associated with the Sea Cucumber Holothuria nobilis Selenka

Guignardia

1 reference

Synergistic Antifungal Meroterpenes and Dioxolanone Derivatives from the Endophytic Fungus Guignardia sp.

Biatriospora

1 reference

Heptaketides from an Endolichenic Fungus Biatriospora sp. and Their Antifungal Activity

medical condition treated

vulvovaginal candidiasis

2 references

13 December 2016

2 October 2018

2 references

13 December 2016

2 October 2018

1 reference

chronic mucocutaneous candidiasis

13 December 2016

1 reference

13 December 2016

1 reference

13 December 2016

2 references

13 December 2016

2 October 2018

1 reference

13 December 2016

1 reference

fungal infectious disease

13 December 2016

1 reference

13 December 2016

esophageal candidiasis

1 reference

2 October 2018

urinary tract infection

1 reference

Food and Drug Administration

2 October 2018

cryptococcal meningitis

start time

28 January 1990

approved by

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/8VZV102JFY

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019949s051lbl.pdf

vulvovaginal candidiasis

start time

28 January 1990

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/8VZV102JFY

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019949s051lbl.pdf

significant drug interaction

simvastatin

1 reference

reference URL

https://www.goodrx.com/drugs/safety/drug-interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

domperidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

uveitis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

aminophylline

1 reference

A reference set of clinically relevant adverse drug-drug interactions

theophylline monohydrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

vincristine

hepatotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

carbamazepin

hepatotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rac-warfarin

retroperitoneal hemorrhage

1 reference

A reference set of clinically relevant adverse drug-drug interactions

acenocoumarol

retroperitoneal hemorrhage

1 reference

A reference set of clinically relevant adverse drug-drug interactions

alfentanil

central respiratory depression

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

kidney failure

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

cholestasis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

paresthesia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

torsades de pointes

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cardiotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pulseless electrical activity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

leukopenia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

anemia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

thrombocytopenia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

diarrhea

1 reference

A reference set of clinically relevant adverse drug-drug interactions

visual impairment

1 reference

A reference set of clinically relevant adverse drug-drug interactions

blindness

1 reference

A reference set of clinically relevant adverse drug-drug interactions

photophobia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eye pain

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

thrombocytopenia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

leukopenia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

diarrhea

1 reference

A reference set of clinically relevant adverse drug-drug interactions

anemia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ataxia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hyperreflexia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nystagmus

1 reference

A reference set of clinically relevant adverse drug-drug interactions

intention tremor

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ataxia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hyperreflexia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nystagmus

1 reference

A reference set of clinically relevant adverse drug-drug interactions

intention tremor

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tacrolimus

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category D

1 reference

English Wikipedia

US pregnancy category C

1 reference

LiverTox likelihood score

English Wikipedia

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Fluconazole

21 May 2017

1 reference

https://www.pfizer.com/products/product-list

cytochrome P-450 CYP2C9 Inhibitor

1 reference

15 March 2018

1 reference

MeSH descriptor ID

D015725

14-alpha demethylase inhibitor

15 March 2018

1 reference

MeSH descriptor ID

D015725

cytochrome P-450 CYP2C19 Inhibitors

15 March 2018

1 reference

InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

15 March 2018

0 references

Fluconazole

0 references

Identifiers

InChI

1 reference

fluconazole (English)

19 November 2016

2 references

fluconazole (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

86386-73-4

2 references

fluconazole (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=86386-73-4

8 April 2021

1 reference

Fluconazole (English)

19 November 2016

2 references

fluconazole (English)

19 November 2016

Reaxys registry number

7311650

1 reference

fluconazole (English)

19 October 2016

ChEBI ID

46081

mapping relation type

2 references

FLUCONAZOLE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

1 reference

FLUCONAZOLE (English)

19 November 2016

2 references

inferred from InChIKey

MSBNK-Eawag_Additional_Specs-ET230001

1 reference

MassBank accession ID

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

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0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

MSBNK-Athens_Univ-AU235257

0 references

MSBNK-Athens_Univ-AU235258

0 references

MSBNK-Athens_Univ-AU235259

0 references

MSBNK-Athens_Univ-AU235260

0 references

SPLASH

splash10-0a4i-0019000000-9ddd55ba2decdc6d3007

0 references

splash10-0079-0091000000-5501d6ab39e3fb2e3676

0 references

splash10-00y0-1690000000-fb006053901bf08be9c9

0 references

splash10-00y0-1920000000-a0f9f745307937304b45

0 references

splash10-00g0-1900000000-f3d3042120b194b579d4

0 references

splash10-00bi-1900000000-8d82f395b99e530cb46e

0 references

splash10-0a4i-0019000000-cf2933c2544adb816b0b

0 references

splash10-0079-0091000000-066891bc3d77fcb69c5d

0 references

splash10-00y0-1590000000-5d278aae398bb4d6c6b6

0 references

splash10-00y0-1920000000-3dcfbc3d71451cc9331c

0 references

splash10-00g0-1900000000-c4af46372e623cdeb3dd

0 references

splash10-0fi9-1900000000-c15061f8dd5425cdede4

0 references

splash10-000i-0090000000-af8c5257ccffbdd94e82

0 references

splash10-0006-0900000000-339ec0708a6a6299e4d1

0 references

splash10-0006-0900000000-ea278fc262275613a1fe

0 references

splash10-0006-0900000000-bbdadb624a7360b26fa3

0 references

splash10-00kf-6900000000-0316b801589bae74a3f9

0 references

splash10-014i-9100000000-d7b76913f55978a00d10

0 references

splash10-014i-9000000000-45cd8f87d45358745d5b

0 references

splash10-014i-9000000000-2f3230e2968762340fb0

0 references

splash10-0006-0900000000-ea0bdd0dd4905f7ca2a7

0 references

splash10-0006-0900000000-643df112c60eecdd6f26

0 references

splash10-00kf-6900000000-636d53fe2393f25b4cc4

0 references

splash10-014i-9100000000-2d05579f16a7ce194afb

0 references

splash10-014i-9000000000-bb834fc848ba7398b278

0 references

splash10-014i-9000000000-e3f46745a82b72dc28b0

0 references

splash10-0006-0900000000-565636d9f9e684b11429

0 references

splash10-0abi-2795000000-c36fbab24191f149ce46

0 references

splash10-05g0-1795000000-7cf5f5c74fd37b2b188f

0 references

splash10-0006-0900000000-224c620bb2943c3558aa

0 references

splash10-00dr-0390000000-5ae132600e3f7f3b30a1

0 references

NMRShiftDB structure ID

20246881

1 reference

HSDB ID

7420

1 reference

Hazardous Substances Data Bank

28 October 2019

FLUCONAZOLE (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

627-806-0

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.156.133

27 December 2018

ECHA Substance Infocard ID

2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol (English)

quotation

CAS no.: 86386-73-4 (English)

100.156.133

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.156.133

27 December 2018

2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol (English)

quotation

CAS no.: 86386-73-4 (English)

1 reference

Fluconazole (English)

17 November 2015

1 reference

Fluconazole (English)

17 November 2015

Fluconazole

0 references

0 references

0 references

1 reference

fluconazole (English)

19 November 2016

DrugBank ID

DB00196

1 reference

Human Metabolome Database ID

HMDB0014342

2 references

inferred from InChIKey

KNApSAcK ID

C00063215

2 references

inferred from InChIKey

2 references

fluconazole (English)

19 November 2016

MedlinePlus drug identifier

a690002

route of administration

oral administration

0 references

a601143

route of administration

intravenous administration

0 references

NDF-RT ID

N0000147613

1 reference

fluconazole (English)

19 November 2016

0 references

1 reference

1 reference

electronic Essential Medicines List medicine ID

Fluconazole (English)

19 January 2016

0 references

0 references

359

0 references

Encyclopedia of China (Third Edition) ID

0 references

1 reference

28 October 2013

Gran Enciclopèdia Catalana ID

fluconazole

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0 references

1 reference

9 July 2020

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

4WMZ (English)

19 October 2016

1 reference

2WV2 (English)

19 October 2016

1 reference

3L4D (English)

19 October 2016

1 reference

4ZE3 (English)

19 October 2016

1 reference

4ZDZ (English)

19 October 2016

1 reference

2IJ7 (English)

19 October 2016

1 reference

3KHM (English)

19 October 2016

1 reference

1EA1 (English)

19 October 2016

1 reference

2WUZ (English)

19 October 2016

1 reference

2WX2 (English)

19 October 2016

1 reference

agricultural-and-biological-sciences/fluconazole

German Wikipedia

ScienceDirect topic ID

0 references

Store medisinske leksikon ID

flukonazol

mapping relation type

exact match

subject named as

flukonazol

1 reference

Great Norwegian Encyclopedia

5 June 2020

1 reference

fluconazole (English)

19 November 2016

C0729170

1 reference