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Gene Therapy Final

The document outlines tasks related to Mendel's laws of genetics, specifically focusing on monohybrid and dihybrid crosses using Punnett squares. It explains Mendel's Law of Segregation and Law of Independent Assortment, detailing the resulting genotypic and phenotypic ratios. Additionally, it discusses somatic gene therapy and differentiates between various gene therapy techniques.

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Reich jan Saysot
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61 views4 pages

Gene Therapy Final

The document outlines tasks related to Mendel's laws of genetics, specifically focusing on monohybrid and dihybrid crosses using Punnett squares. It explains Mendel's Law of Segregation and Law of Independent Assortment, detailing the resulting genotypic and phenotypic ratios. Additionally, it discusses somatic gene therapy and differentiates between various gene therapy techniques.

Uploaded by

Reich jan Saysot
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Republic of the Philippines

SURIGAO DEL NORTE STATE UNIVERSITY


Narciso Street, Surigao City 8400, Philippines
“For Nation’s Greater

Name: SALIBAY, REICH JAN S. Date: 04-07-


2025
Course: BSED-FILIPINO 2B
ACTIVITY: GENE THERAPY
TASK 1. Make a graphic organizer of gene therapy types and techniques.
Instruction. Do the 2 tasks on the law of Mendel. Accomplish the tasks below which
correspond on the Punnett square of the characteristics of offspring (task 1). And task 2 for
Dihybrid cross.

TASK 1: MONOHYBRID CROSS – Mendel’s Law of Segregation

Description:

The diagram shows a 2x2 Punnett square for flower color:

 P (purple) is dominant
 p (white) is recessive
Each parent is heterozygous (Pp), so the cross is Pp × Pp.

The resulting genotypes are:

 1 PP (homozygous dominant – Purple)


 2 Pp (heterozygous – Purple)
 1 pp (homozygous recessive – White)

Explanation:

This illustrates Mendel's Law of Segregation, which states that during gamete formation, the two alleles for a gene
separate so that each gamete carries only one allele. When fertilization occurs, offspring inherit one allele from
each parent, resulting in a 3:1 ratio of dominant to recessive traits.
TASK 2: DIHYBRID CROSS – Mendel’s Law of Independent
Assortment

Description:

The 4x4 Punnett square shows a dihybrid cross for:

 Seed color: Yellow (Y) vs Green (y)


 Seed shape: Round (R) vs Wrinkled (r)
Each parent is heterozygous for both traits (YyRr × YyRr), producing gametes: YR, Yr, yR, yr.

The resulting phenotypic ratio is:

 9 Yellow-Round
 3 Yellow-Wrinkled
 3 Green-Round
 1 Green-Wrinkled

Explanation:

This follows Mendel’s Law of Independent Assortment, which states that genes for different traits are passed
independently of one another from parents to offspring. The [Link] ratio appears when two traits are inherited together
from heterozygous parents.
Guide Questions:

1. How somatic gene therapy can be used to treat and how it is passed on the offspring?
Somatic gene therapy treats genetic diseases by introducing functional DNA into non-reproductive body cells.
It corrects gene defects at the cellular level. Since it does not affect egg or sperm cells, the changes are not
inherited and cannot be passed on to offspring.

2. Differentiate gene therapy techniques.


 Gene Augmentation Therapy: Adds a healthy gene to replace a non-functioning one.
 Gene Inhibition Therapy: Shuts down or silences faulty genes causing disease.
 Cell-Killing Therapy: Introduces DNA to eliminate diseased cells, often used for cancer treatment.

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