Clinical Biochemistry of Domestic Animals
Clinical Biochemistry of Domestic Animals
Clinical Biochemistry of Domestic Animals
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Kaneko JJ, Harvey JW, Bruss ML. Clinical Biochem- The current edition contains 30 chapters, compared
istry of Domestic Animals, 5th ed. Academic Press, with the previous edition with 28 chapters. The chapter
San Diego, California, 1997. 931 pp. ISBN 0-12- on 'Trace Elements' has been removed, the previous
396305-2. $120.00 US. 2 chapters on 'Ketogenesis and Ketosis' and on 'Lipid
Metabolism and Its Diseases' have been joined within
This is an internationally recognized reference textbook 'Lipids and Ketones'. Four new chapters have been
in animal clinical biochemistry that replaces the pre- added: 'Tumor Markers, Lysosomal Storage Diseases,
vious edition published in 1989. Although the format Clinical Biochemistry in Toxicology, and Avian Clinical
remains the same, there are many changes in addition to Biochemistry.' The majority of authors remain the same
the most important feature, namely, the incorporation of for this edition, although there are several changes and
a wealth of new information developed during the inter- additions of new names. The scientific information
vening years. Two internationally recognized authorities included in the new chapters will appeal to very differ-
have been added as associate editors to guide the prepa- ent and potentially new readers of this book.
ration of this edition. The dimensions of the pages are Although the chapters differ in outline, in general, each
larger, but this is counterbalanced by an increase in begins with an introduction and brief review of normal
font size resulting in a similar total number of pages. function or anatomical considerations and physiology,
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the clinical signs associated with major organ system dis- the central 95% reference limits, would greatly improve
orders or diseases, and methods of analysis and inter- the scientific value of the reference values included in the
pretation. Each chapter provides an independent and Appendix. Readers should be cautioned against using
broad source of information valuable to all clinicians, stu- these reference values for any more than relative infor-
dents, teachers, and researchers as a source of original mation, until they have been validated for the methods
information for review or for updating. It is interesting used in their laboratory. A minor typographical error is
that this textbook can be perceived as containing too noted in Table 1.1 where 'dogs' are referred to in the title
much detail for undergraduate students and general- but 'cows' are listed as the source of animals.
ists, but too little information for graduate students or Although I have not yet read all chapters in detail, it
specialists. For the latter, the extensive references pro- is apparent that there is much new and updated infor-
vide comprehensive sources of additional detail. mation in this edition. There are too many changes to
Incorporation of both the traditional and the 'sys- address each in detail, but, as an example, the new
teme international d'unites' is very much appreciated by authors have incorporated their collective clinical and lab-
international readers. The chapter on the 'Concepts of oratory experience in the revisions to the chapter on cere-
Normality in Clinical Biochemistry' was examined brospinal fluid. The new chapter on 'Avian Clinical
with interest, because of the great significance to every- Biochemistry' provides a major resource for both clin-
one generating or interpreting laboratory data. The icians and researchers in this area of increased interest.
reviewer is interested in the information presented, yet The editors and authors are to be congratulated on their
had to read this chapter very carefully in order to com- revisions and contributions to a major resource for ani-
prehend the authors' opinion about several points of mal clinical biochemistry. The current information
major interest and concern. should be used as a pnrmary resource for students study-
Since this textbook is read by the majority of the ing disease and clinicians differentiating disease, and as
contributors to this aspect of clinical biochemistry, this an initial resource for researchers and graduate stu-
chapter provides an opportunity to present simple guide- dents studying biochemical changes in health and disease.
lines for establishing reference values, including data
analysis. As an example to illustrate these concepts, Reviewed by John H. Lumsden, DVM, Professor,
additional information including methods used, source Veterinary Clinical Pathologist, Department of
and number of individuals sampled, the methods used for Pathology, Ontario Veterinay College, University of
calculating lower and upper limits, and if they represent Guelph, Guelph, Ontario NJG 2W].