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Meta Analysis in Literature Review

The document discusses conducting a meta-analysis within a literature review. It explains that a meta-analysis requires synthesizing data from multiple studies to draw conclusions, and involves conducting a thorough literature search, extracting relevant data from studies, and synthesizing findings. It also notes that performing a meta-analysis requires advanced statistical skills to calculate effect sizes and assess heterogeneity among studies. The document recommends seeking professional assistance to ensure the literature review meets academic standards, as meta-analyses require significant effort and expertise.

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100% found this document useful (2 votes)
56 views6 pages

Meta Analysis in Literature Review

The document discusses conducting a meta-analysis within a literature review. It explains that a meta-analysis requires synthesizing data from multiple studies to draw conclusions, and involves conducting a thorough literature search, extracting relevant data from studies, and synthesizing findings. It also notes that performing a meta-analysis requires advanced statistical skills to calculate effect sizes and assess heterogeneity among studies. The document recommends seeking professional assistance to ensure the literature review meets academic standards, as meta-analyses require significant effort and expertise.

Uploaded by

dafobrrif
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

meta analysis in literature reviewPrevent plagiarism. Run a free check.

A systematic review is a good choice of


review if you want to answer a question about the effectiveness of an intervention, such as a medical treatment.
This will help keep the data organized and help the researcher focus on exactly which data needs to be extracted.
Efficacy of sotrovimab on omicron BA.2, BA.4 and BA.5. Background: The aim of this meta-analysis was to
ascertain whether sotrovimab was effective in reducing COVID-19 related hospitalization and mortality also in
Omicron BA.2, BA.4 and BA.5 subvariants compared to other antivirals effective in index period. The main
reason is that the observational studies may entail an increased risk of biases and high levels of heterogeneity.
Meurer, MD, MPH Department of Family and Community Medicine. “Systematic Synthesis of the Literature:
Introduction to Meta-analysis”. Meta-analyses of observational studies such as cohort studies are frequently
performed, but no widely accepted guidance is available at the moment. My supervisors had pushed me to explain
what kind of realist review I intended to undertake, and I found out there was a branch of critical realism which
was briefly of interest. Were the groups similar at baseline in terms of prognostic factors. Similar to a systematic
review, a scoping review is a type of review that tries to minimize bias by using transparent and repeatable
methods. Step 2: Develop a protocol A protocol is a document that contains your research plan for the systematic
review. Supplementary Information Additional file 1.. Search Term Additional file 2: Table S1. JBI Manual for
Evidence Synthesis The JBI Manual for Evidence Synthesis is designed to provide authors with a comprehensive
guide to conducting JBI systematic reviews. Systematic reviews typically answer their research question by
synthesizing all available evidence and evaluating the quality of the evidence. Systematic review is a type of
literature review that uses systematic methods to collect secondary data, critically appraise research studies, and
synthesise findings. People aged ?18?years old showed a higher HBV prevalence. This also helps avoid
formulating decisions exclusively based on the outcomes or studies of your findings. This is the median control
group risk across 8 trials of 3,663 women. If the key findings disappear, then the conclusions need to be
expressed more cautiously. Review purpose of a Systematic Review Types of systematic review Best question for
each study type Process of designing a systematic review. Statswork offers expert consulting assistance and
enhancing researchers by our distinct statistical process and communication throughout the research process with
us.

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Meta Analysis In Literature Review
Seroepidemiological survey of hepatitis B among children in Milin county of Tibet 2020. In addition to the focus
and transparency of these types of reviews, additional aspects of a quality systematic literature review includes:
Clear and concise review and summary Comprehensive coverage of the topic Accessibility and equality of the
research reviewed Systematic Review vs Literature Review The difference between literature review and
systematic review comes back to the initial research question. A systematic review is secondary research because
it uses existing research. If you don’t have enough data, or the data from different studies aren’t
comparable, then you can take just a narrative approach. This presented review had fewer studies on the
prevalence of HBV in rural and urban areas, which would lead to a reduction in HBV prevalence in rural and
urban areas. Or, you can decide to explore a different research method (perhaps more qualitative). This process is
more ad hoc for literature reviews. Data Extraction Tip 5: Communicate Regularly The Covidence Global
Scholarship recipients are putting evidence-based research into practice. The advent of evidence-based medicine
has increased the demand for systematic methods to analyze and synthesize clinical evidence. The prevalence of
HBV varied in different age groups. As an assignment For a report or thesis (e.g. for senior project) As a graduate
student For a technical paper. It’s a statistical analysis that combines the results of two or more studies,
usually to estimate an effect size. For example, the 95% confidence interval for the paper written by Steele and
Turner was 1.1- 2.1. The 95% part just means that the statistical software told the researchers that they can be 95%
sure that the relative risk is in this range. There is not a necessity to restrict your study to only numerical data
which can be meta-analyzed. To reduce bias, it’s important to search for relevant studies very thoroughly.
DR. SEAS is an easy way to help remember that the steps of doing a meta-analysis are. Pharmaceutical
companies use meta-analysis to gauge their model’s generalizability, developing and validating different
prediction models. The studies selected to be included add strength to the analysis. However, a scoping review
isn’t a type of systematic review. However, we strongly advise against trying to pass AI-generated text off as
your own work.

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Meta Analysis In Literature Review
They often, in fact, identify lack of evidence or knowledge limitations, and consequently recommend further
study, if needed. CINeMA: an approach for assessing confidence in the results of a network meta-analysis. PLoS
Med. 2020;17(4):e1003082. Investigation on prevalence of HBsAg and HBsAb in population aged 1 to 69 years
in Jiangxi Province in 2020. Meta-analysis. Department of Education, University of Oxford. Session 2.3:
Assessing Quality. If you are proposing to perform a systematic review these provide invaluable detailed advice,
and useful examples. Please see our Privacy Policy for more information. Annual trends in arthroscopic meniscus
surgery: analysis of a national database in Japan. PLoS One. 2018;13(4):e0194854. The Steps of a Meta-Analysis
DR. SEAS is an acronym to help remember the steps for doing a meta-analysis. High-quality systematic reviews
and meta-analyses take great care to find all relevant studies, critically assess each study, synthesize the findings
from individual studies in an unbiased manner, and present balanced important summary of findings with due
consideration of any flaws in the evidence. The researcher performing a meta-analysis study must be sure that the
research methods measured what they were supposed to measure. A meta-analysis is a statistical analysis, not a
type of review. Step 2: Develop a protocol A protocol is a document that contains your research plan for the
systematic review. Systematic reviews strive to be as thorough and rigorous as possible to minimise the bias that
would result from cherry-picking studies in a non-systematic way. Next, the reviewers extract the relevant data
and assess the quality of the included studies. Using our example, it would mean that these researchers found that
using oral contraceptives for 10 or more years did not increase the risk for developing cervical cancer. Meta-
analysis denotes the statistical analysis of the data from other independent fundamental studies that focus on the
same question. The next steps, S elect appropriate studies, E xtract data, A nalyze data, and S ynthesize data, are
represented by the SEAS in the acronym. 1. Define Research Question and Review Literature Meta-analyses
begin with defining the research question. It supports reviewers with study selection, data extraction and quality
assessment. An annotated bibliography might suffice for a literature review. For instance, the intervention may
work differently in different contexts, and the included studies were gathered from all over the world.

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Meta Analysis In Literature Review
Lancet Region Health-Western Pacif. 2021;16:100267.. Sun Q, Lao TT, Du M, Xie M, Sun Y, Bai B, et al. In:
Espregueira-Mendes, J., Karlsson, J., Musahl, V., Ayeni, O.R. (eds) Orthopaedic Sports Medicine. Explore data
(heterogeneity) Synthesize the data descriptively and inferentially via meta-analysis if appropriate. North Am J
Med Sci. 2011;4(1) World Health Organization. A literature review is a type of review that uses a less systematic
and formal approach than a systematic review. Anti-HBs levels in children under the age of two years born to
HBV carrier mothers after immunoprophylaxis: a multicenter cross-sectional study. Publication bias assessment
was tested by Egger’s test and funnel plot. Literature searching Key Sources Books Journal Articles and
Databases Grey Literature Theses. But it is not always required, and sometimes meta-analysis is conducted
without the context of systematic analysis, as in the case of clinical trials. There are various guides found which
outline how to undertake a meta-analysis in clinical research. The components of a systematic literature review
are quite different from the standard literature review research theses that most of us are used to (more on this
below). Now, they also include any evidence-based research questions. There’s more work related to a
systematic literature review, so it makes sense to divide the work among two or three (or even more) researchers.
Ideally, clinical decision making ought to be based on the latest evidence available. Among the available electronic
scientific database, the popular ones are PUBMED, MEDLINE, and EMBASE. How did the control group score
on the assessments in comparison to the test group. Preregistration gives other researchers confidence that the
team is not selectively choosing advantageous results at the end to make an interesting paper. Each term refers to
research about research, but there are important differences. How many patients does case series should have In
comparison to case reports. The rows represent each study included in the review, and the columns indicate the
review authors’ determination about potential bias in each study.

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Meta Analysis In Literature Review


If the answer was Yes, the item got 1 point, and if the answer was No or Unclear, the item got 0 points. It is
therefore an approach for systematically combining pertinent qualitative and quantitative study data from several
included studies to establish a single conclusion that has significant statistical power. The Guide explores different
approaches and methods for expedited synthesis of health policy and systems research, and highlights key
challenges for this emerging field, including its application in low- and middle-income countries. Data Extraction
Tip 4: Extract the Right Amount of Data Data Extraction Tip 3: Pilot the Template Better systematic review
management, head office, working for an institution or organisation. There are two main approaches to
synthesizing the data: Narrative ( qualitative ): Summarize the information in words. After these criteria have been
decided upon, the researcher will use the abstract, or summary, of each study to make an initial decision to
include or exclude it. The components of a systematic literature review are quite different from the standard
literature review research theses that most of us are used to (more on this below). Because of this, when carried
out well, they provide reliable estimates about the effects of interventions so that conclusions are defensible.
Keywords: COVID-19; early treatment; hospitalization; monoclonal antibodies; mortality. BMC Pub Health.
2023;23(1):256.. He L, Pan X, Yang J, Ma Q, Jiang J, Wang W, et al. Systematic reviews result in high-quality
secondary data that concretely substantiates the case made. The rows represent each study included in the review,
and the columns indicate the review authors’ determination about potential bias in each study. There’s
more work related to a systematic literature review, so it makes sense to divide the work among two or three (or
even more) researchers. This question, in and of itself, is highly focused to match the review of the literature
related to the topic at hand. Heterogeneity means diversity (and is the opposite of homogeneity). Looking at the
forest plot's confidence interval, which indicates the possible ranges of values for a statistical measure, is also an
important part of the process, as is looking at the null line, which indicates significance of the findings. How
would you make a decision if you read 30 studies that said a weight loss treatment worked and 30 that said it
didn't work. Were the groups similar at baseline in terms of prognostic factors. Analysis of seroepidemiological
survey of hepatitis B among people aged 0-79 years in Zhengzhou from 2019 to 2021. Language Editing Plus
includes checking the logic and flow of your manuscript, reference checks, formatting in accordance to your
chosen journal and even a custom cover letter.

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Meta Analysis In Literature Review

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