Clinical Pharmacy Quiz
Clinical Pharmacy Quiz
Clinical Pharmacy Quiz
General Instructions:
1. Use a half crosswise sheet of yellow pad paper for your answers. Write your complete name on the
top left portion of the sheet, and "Clinical Pharmacy Quiz" beside your name.
2. No need to write down the questions; just write your answers in an organized manner.
3. Submit your papers to Ms. Faye on September 1, 2018 (Saturday) prior to taking the Module 3
Exam.
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5. Usage of methotrexate puts the user at greater risk of:
a. Visual impairment
b. Heart attack
c. Anaphylactic shock
d. Infection
PART 2: Drug Interactions (10 points)
Instruction: Select the BEST answer from the following choices, and indicate the pharmacological rationale
for your chosen answer (reference not required).
Sample Question:
Eating a lot of bananas while on spironolactone therapy may lead to:
a. Increase in the body's sodium levels
b. Increase in the bioavailability of spironolactone
c. Increase the body's potassium levels
d. Decrease in the excretion of spironolactone
Sample Answer:
C - Spironolactone is a potassium-sparing diuretic which works by blocking the excretion of potassium ions
in the collecting duct of the kidney tubules. Eating banana, which is rich in potassium, while on
spironolactone therapy may lead to hyperkalemia.
1. Griseofulvin, when taken with fatty food, affects drugs by:
a. Increasing the BA of drugs
b. Decreasing the BA of drugs
c. No effect on BA of drugs
d. Increasing the rate of excretion of drugs
2. Digoxin and quinidine, when taken concomitantly, may lead to:
a. Decreased quinidine effect
b. Decreased digoxin effect
c. Increased risk for digitalis toxicity
d. Increased risk for quinidine toxicity
3. Sildenafil and isosorbide mononitrate, when taken concomitantly, may lead to:
a. Increased thrombotic effect
b. Increased hypotensive effect
c. Increased hypertensive effect
d. Increased bradycardic effect
4. Methotrexate and probenecid, when taken concomitantly, may lead to:
a. Decreased levels of methotrexate
b. Increased levels of methotrexate
c. Decreased levels of probenecid
d. Increased levels of probenecid
5. Clonidine and propranolol, when taken concomitantly, may lead to:
a. Increased risk for tachycardia
b. Increased risk for bradycardia
c. Increased risk for hypokalemia
d. Increased risk for hyperkalemia
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PART 3: Medication Errors (5 points)
Instruction: Indicate the accurate category of medication error committed based on the NCCMERP
guidelines.
1. A physician prescribed the adult dosage for an antibiotic to a pediatric patient. Upon arrival at the
local pharmacy, the pharmacist detected the error, and called the patient's physician for
reconciliation. The pharmacist dispensed the antibiotic in its correct dosage, and provided
counseling to the patient's guardian.
2. A pharmacy attendant dispensed a different oral contraceptive to a patient than the one prescribed
by the patient's gynecologist. Four months later, the patient was admitted to a hospital after being
diagnosed with deep vein thrombosis.
3. An adult male took an overdose of ibuprofen after feeling extreme pain from running a marathon.
The patient had himself checked at the nearest hospital after feeling pain in his lower abdomen. He
was told that his liver enzymes had to be monitored for sudden changes.
4. An adult female patient took an incorrect dosage of amlodipine which caused her to experience
tachycardia. The patient was rushed to the emergency room, and was administered first aid
treatment. The patient was released after five hours after her heart rate stabilized.
5. The patient was prescribed isotretinoin for acne. She did not inform her dermatologist that she got
pregnant, and continued taking the medication as prescribed. Upon giving birth, it was determined
that her neonate developed several anomalies due to isotretinoin.
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