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    Drug Study Ceftriaxone Sodium

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    Princess Queenie Olarte
    This document provides information about the drug Rocephin (generic name Ceftriaxone Sodium), a third-generation cephalosporin antibiotic. It lists recommended dosages by route and frequency for various conditions. Potential drug interactions and contraindications are noted. Common adverse effects include headache, nausea, diarrhea and injection site reactions. Nurses are responsible for assessing patients for allergic reactions, monitoring injection sites, and educating patients about reporting side effects like bleeding or diarrhea.

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    Drug Study Ceftriaxone Sodium

    Uploaded by

    Princess Queenie Olarte
    774 views3 pages
    This document provides information about the drug Rocephin (generic name Ceftriaxone Sodium), a third-generation cephalosporin antibiotic. It lists recommended dosages by route and frequency for various conditions. Potential drug interactions and contraindications are noted. Common adverse effects include headache, nausea, diarrhea and injection site reactions. Nurses are responsible for assessing patients for allergic reactions, monitoring injection sites, and educating patients about reporting side effects like bleeding or diarrhea.

    Original Description:

    Nursing Drug Study

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    This document provides information about the drug Rocephin (generic name Ceftriaxone Sodium), a third-generation cephalosporin antibiotic. It lists recommended dosages by route and frequency for various conditions. Potential drug interactions and contraindications are noted. Common adverse effects include headache, nausea, diarrhea and injection site reactions. Nurses are responsible for assessing patients for allergic reactions, monitoring injection sites, and educating patients about reporting side effects like bleeding or diarrhea.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    774 views3 pages

    Drug Study Ceftriaxone Sodium

    Uploaded by

    Princess Queenie Olarte
    This document provides information about the drug Rocephin (generic name Ceftriaxone Sodium), a third-generation cephalosporin antibiotic. It lists recommended dosages by route and frequency for various conditions. Potential drug interactions and contraindications are noted. Common adverse effects include headache, nausea, diarrhea and injection site reactions. Nurses are responsible for assessing patients for allergic reactions, monitoring injection sites, and educating patients about reporting side effects like bleeding or diarrhea.

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    DRUG STUDY

    Brand Name: __Rocephin____ Generic Name: _Ceftriaxone Sodium_ Drug Classification: _Antiinfective; Antibiotic; Third - Generation Cephalosporin_

    Dosage, Route & Frequency Drug-Drug & Adverse


    Contraindication Side Effects
    Drug Action Drug-Food Indications Reactions (By
    Recommended Prescribed s (By System)
    Interactions System)
    Moderate to 100 mg/kg/day, Semisynthetic third- Interactions Infections caused Hypersensitivity to CNS: Headache, Body as a
    Severe generation Drug: by susceptible cephalosporins dizziness, lethargy Whole: Pruritus,
    Infections cephalosporin Probenecid organisms in and related GI: Nausea, fever, chills, pain,
    vomiting, diarrhea,
    antibiotic. decreases renal lower respiratory antibiotics; induration at IM
    Child: IV/IM 50– anorexia,
    Preferentially binds to elimination of tract, skin and pregnancy pseudomembrano injection site;
    75 mg/kg/d in 2 one or more of the ceftriaxone; skin structures, (category B). phlebitis (IV site).
    us colitis
    divided doses penicillin-binding alcohol produces urinary tract, HEMATOLOGIC:
    (max: 2 g/d) proteins (PBP) located disulfiram bones and joints; bone marrow GI: Diarrhea,
    on cell walls of reaction. also intra- depression–dec. abdominal
    Meningitis
    susceptible organisms. abdominal WBC, platelets, cramps,
    Child: IV/IM 75 Hct pseudomembrano
    This inhibits third and infections, pelvic
    LOCAL: pain, us colitis, biliary
    mg/kg loading final stage of bacterial inflammatory inflammation of IV sludge.
    dose, then 100 cell wall synthesis, disease, Site
    mg/kg/d in 2 thus killing the uncomplicated OTHER: Urogenital:
    divided doses bacterium. gonorrhea, superinfections, Genital pruritus;
    (max: 4 g/d) meningitis, and disulfiram-like
    moniliasis.
    surgical reaction with
    alcohoL
    Pharmacokinetics prophylaxis.

    Peak: 1.5–4 h after IM;


    immediately after IV
    infusion.

    Distribution: Widely
    distributed in body
    Patient’s Name / Room No. | 1
    tissues and fluids;
    good CNS penetration,
    especially with
    inflamed meninges;
    crosses placenta.

    Metabolism: Not
    metabolized.

    Elimination: 33–65%
    excreted unchanged in
    urine; also excreted in
    bile; small amount
    excreted in breast milk.

    Half-Life: 5–10 h.

    Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)

    Assessment & Drug Effects Patient & Family Education

    ● Determine history of hypersensitivity reactions to cephalosporins and ● Report any signs of bleeding.
    penicillins and history of other allergies, particularly to drugs, before ● Report loose stools or diarrhea promptly.
    therapy is initiated. ● Do not breast feed while taking this drug without consulting physician
    ● Lab tests: Perform culture and sensitivity tests before initiation of therapy
    and periodically during therapy. Dosage may be started pending test
    results. Periodic coagulation studies (PT and INR) should be done.
    ● Inspect injection sites for induration and inflammation. Rotate sites. Note
    IV injection sites for signs of phlebitis (redness, swelling, pain).
    ● Monitor for manifestations of hypersensitivity (see Appendix F). Report
    their appearance promptly and discontinue drug.
    ● Watch for and report signs: petechiae, ecchymotic areas, epistaxis, or
    Patient’s Name / Room No. | 2
    any unexplained bleeding. Ceftriaxone appears to alter vitamin K–
    producing gut bacteria; therefore, hypoprothrombinemic bleeding may
    occur.
    ● Check for fever if diarrhea occurs: Report both promptly. The incidence of
    antibiotic-produced pseudomembranous colitis (see Appendix F) is higher
    than with most cephalosporins. Most vulnerable patients: chronically ill or
    debilitated older adult patients undergoing abdominal surgery.

    Patient’s Name / Room No. | 3

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