15 Mixing Medications Using One Syringe

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Mixing Medications Using One Syringe

Equipment:
 Client’s Medication Administration Record (MAR) or computer printout
 Two vials of medication
** one vial and one ampule
** two ampules OR
** one vial or one ampule and one cartridge

 Antiseptic swabs
 Sterile syringe and safety needle OR insulin syringe and needle (if insulin
syringe is being given, use a small-gauge hypodermic needle, e.g., #26
gauge)

 Additional sterile subcutaneous or intramuscular safety needle (optional)


 
No. Steps Rationale
  Preparation:  
 1 Check the MAR.  
 Check the label on the medications
carefully against the MAR to make sure
that the correct medication is being
prepared.
 Follow the three checks for administering
medications. Read the label on the
medication (1) when it is taken from the
medication cart, (2) before withdrawing the
medication, and (3) after withdrawing the
medication.
 Before preparing and combining the
medications, ensure that the total volume
of the injection is appropriate for the
injection site.
2 Organize equipment.
  Steps:  
1 Perform hand hygiene and observe other
appropriate infection prevention procedures.
2 Prepare the medication ampule or vial for
medication withdrawal.
 Prepare the medications to be withdrawn. Preparations that have
 While preparing medications from an changed in appearance
ampule or vial, inspect the appearance for should be discarded.
clarity. Note, however, that some
medications are always cloudy.
 Clean the top of the vials with antiseptic This avoids contamination of
swabs. the medication once the
needle is inserted for
medication withdrawal.
3 Withdraw the medications.

Mixing Medications from Two Vials


 Take the syringe and draw up a volume of
air equal to the volume of medications to be
withdrawn from both vials A & B.
 Inject a volume of air to the volume of This prevents cross
medication to be withdrawn into vial A. contamination of the
Make sure the needle does not touch the medications because the
solution. same needle will be used for
 Withdraw the needle from vial A and inject vial B.
the remaining air into vial B.
 Withdraw the required amount of The same needle is used to
medication from vial B. inject air into and withdraw
medication from the second
vial.
 Remove and properly discard the needle
then replace with a new sterile needle.
 Using a newly attached sterile needle, With this method, neither of
withdraw the required amount of medication the vial is contaminated by
from vial A. Avoid pushing the plunger of microorganisms or by
the syringe because it will introduce medication from the other
medication B into vial A. vial.
Be careful to withdraw only the desired The syringe now contains
amount and to not create air bubbles. the two medications and an
excess amount cannot be
returned to the vial.

Mixing Medications from One Vial and One


Ampule
 Prepare first and withdraw the medication Ampules do not require
from the vial. injection of air prior to
withdrawal of medication.
 Withdraw the required amount of
medication from the ampule.
4 Cover the top of the vial and/or ampule securely This maintains the shelf life
with clean adhesive then store appropriately. of the medication/s.
5 Discard appropriately the used needle and For safety purpose and
supplies. cleanliness of the
medication cart

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