UNIVERSITY OF CAMBRIDGE INTERNATIONAL EXAMINATIONS

General Certificate of Education

Advanced Subsidiary Level and Advanced Level

BIOLOGY 9700/01
Paper 1 Multiple Choice October/November 2007
1 hour
Additional Materials: Multiple Choice Answer Sheet
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IB07 11_9700_01/5RP
© UCLES 2007 [Turn over
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1 The diagram shows part of a membrane around a vacuole of a plant cell.

scale bar
2 nm

What is the width of the membrane?

A 7.5 × 10–3 m

B 7.5 × 10–6 m

C 7.5 × 10–9 m

D 7.5 × 10–12 m

2 The diagram is taken from an electron micrograph of a cell which secretes digestive enzymes.

Where are these enzymes made?

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3 A specimen is viewed under a microscope using green light with a wavelength of 510 nm.

If the same specimen is viewed under the same conditions, but using red light with a wavelength
of 650 nm instead, what effect will this have on the magnification and on the resolution of the
microscope?

magnification resolution

A decreased decreased
B increased increased
C remains the same increased
D remains the same decreased

4 The diagram shows a transverse section of part of a dicotyledonous leaf.

What are the correct labels for 1, 2, 3 and 4?

1 2 3 4

A phloem xylem palisade mesophyll spongy mesophyll

B phloem xylem spongy mesophyll palisade mesophyll
C xylem phloem palisade mesophyll spongy mesophyll
D xylem phloem spongy mesophyll palisade mesophyll

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5 A student is asked to study two photographs, taken at the same magnification, of a palisade
mesophyll cell, one using a high quality light microscope and the other using an electron
microscope.

The student observed

1 the cisternae of the Golgi apparatus

2 the grana in the chloroplasts
3 the two membranes of the nuclear envelope
4 the vacuole enclosed by a tonoplast
Which features can be seen because of the higher resolution of the electron microscope?

A 1, 2 and 3
B 1, 2 and 4
C 1, 3 and 4
D 2, 3 and 4

6 The diagram shows a photomicrograph. Its magnification is ×2800.

What is the diameter of the nucleolus?

A 2.5 µm B 5 µm C 10 µm D 20 µm

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7 When solutions of dilute sodium hydroxide and copper(II) sulphate (biuret test) were added to an
unknown substance, a purple colour was observed.

This test indicates the presence of which bond in the unknown substance?

A disulphide
B hydrogen
C ionic
D peptide

8 The diagram shows part of a macromolecule in the form of triple helices, lying side by side with
covalent cross links between them.

What is the name of the molecule?

A cellulose
B collagen
C glycogen
D triglyceride

9 Which of the following is a polysaccharide present in human muscle?

A amylose
B collagen
C glycogen
D haemoglobin

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10 An investigation was carried out into the effect of various chemicals on the permeability of the
plasma membrane and tonoplast of beetroot cells. Beetroot cell vacuoles contain a red pigment,
which cannot pass out of the cells because it cannot diffuse through their tonoplasts and plasma
membranes.

1 cm3 cubes were cut from beetroot and washed in running water for twenty minutes to remove
any pigment released from damaged cells.

They were then placed in different solutions and the results observed. In each case the solution
turned red.

What shows the correct behaviour of phospholipids and proteins in different solutions?

phospholipids protein
solution solution
dissolve denatures

A dilute HCl water at 40 oC

B dilute HCl ethanol
C ethanol dilute HCl
D water at 40 oC ethanol

11 The diagram shows a phospholipid molecule.

H H O

H C C C H

O O H

C O C O

Z Y

What are X, Y and Z?

X Y Z

A hydrocarbon chain hydrocarbon chain phosphate-containing group

B hydrocarbon chain glycerol phosphate-containing group
C phosphate-containing group hydrocarbon chain hydrocarbon chain
D phosphate-containing group glycerol hydrocarbon chain

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12 The diagrams show four different molecules.

P Q

CH2OH CH2OH
C O H O
H H H N C C
C C H OH
HO OH H OH H
C C
H OH

R S

CH2OH O OH
C O C
H H OH
C C CH2
HO OH H H H O
C C N C C
H OH H OH
H

Which shows the correct information about the molecule or molecules?

contains a forms 1,6 glycosidic forms peptide bonds

carboxyl group bonds in glycogen by condensation

A P P P and Q
B Q R P and R
C R R R and Q
D S P Q and S

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13 The graph shows the effect of an enzyme on a reaction.

transition
state

X
energy of
system substrate Y

Z
product

time

Which combination identifies X, Y and Z?

X Y Z

A catalysed reaction uncatalysed reaction activation energy

B catalysed reaction uncatalysed reaction energy lost during reaction
C uncatalysed reaction catalysed reaction energy gained by product
D uncatalysed reaction catalysed reaction overall energy change

14 Which graph represents the action of a non-competitive inhibitor?

A B

maximum maximum

rate of rate of
reaction reaction

concentration of substrate concentration of substrate key

without inhibitor
C D with inhibitor
maximum maximum

rate of rate of
reaction reaction

concentration of substrate concentration of substrate

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15 Strips of plant tissue were immersed in a range of sucrose solutions of different concentrations.
Their lengths were measured before immersion and after 30 minutes.

The graph shows the ratio of initial length to final length.

1.4

1.2

initial length 1.0

final length
0.8

0.6

0.4
0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8

sucrose concentration / mol dm–3

What is a correct description of the change in the cells and in their water potential as the sucrose
concentration increases?

change in the cells change in the water potential

A more turgid less negative

B less turgid more negative
C more turgid more negative
D less turgid less negative

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16 The graph shows rates of simple diffusion and facilitated diffusion, of substance X across a cell
surface membrane, as the concentration of substance X increases.

simple diffusion

rate of facilitated diffusion

diffusion /
arbitrary
units

concentration of substance X

Why does the rate of facilitated diffusion level off whereas the rate of simple diffusion does not?

A Facilitated diffusion is limited by the number of protein channels in the membrane.

B Facilitated diffusion is limited by the number of protein pumps in the membrane.
C Facilitated diffusion requires ATP which will eventually be used up.
D Only facilitated diffusion is affected by the kinetic energy of the molecules that are diffusing.

17 Which part of a phospholipid molecule makes up most of the thickness of a cell surface
membrane?

A glycerol
B hydrocarbon chains
C hydrophilic head
D phosphate group

18 Which of the following is true of cancer?

A Each mitotic division produces more than two daughter cells.

B Mitosis has stopped.
C Mitosis is uncontrolled.
D Mitosis results in cells with variable numbers of chromosomes.

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19 Each of the following events takes place during mitosis.

1 centromeres divide
2 chromatids move to opposite poles of the cell
3 chromosomes line up along the equator of the spindle
4 chromosomes uncoil
5 two chromatids are joined by a centromere

In which order do the events take place?

first last

A 1 2 4 5 3
B 3 1 2 4 5
C 4 5 3 1 2
D 5 3 1 2 4

20 The diagram shows part of a DNA molecule.

Where are hydrogen bonds found?

A
B

21 Which type of molecule is the end product of translation?

A amino acid
B DNA
C mRNA
D polypeptide

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22 An unidentified single-stranded molecule was described as having the following features.

• complementary base pairing along some of its length

• an area that can attach to a ribosome

• a site to which a specific amino acid attaches

What is the unidentified molecule?

A DNA polymerase
B messenger RNA
C RNA polymerase
D transfer RNA

23 Some antibacterial drugs can affect the synthesis of proteins.

antimicrobial
rifampicin streptomycin tetracycline
drug
mode of binds to RNA genetic code misread prevents binding of
action polymerase during translation tRNA to ribosome

Which is the correct set of immediate effects of these drugs?

antimicrobial
rifampicin streptomycin tetracycline
drug

A defective protein mRNA does not bind to amino acids not added
synthesised ribosome to growing chain
B mRNA not synthesised defective protein amino acids not added
synthesised to growing chain
C mRNA not synthesised mRNA does not bind to transcription prevented
ribosome
D transcription prevented defective protein mRNA does not bind to
synthesised ribosome

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24 The diagram represents the phloem pathway, with adjacent cells, from leaf to root in a plant.

2
leaf cell 1

chloroplast parenchyma cell

nucleus

companion cell

root cell

Which process is occurring between 1 to 2 and what is the effect on the water potential at 2?

process from 1 to 2 water potential at 2

A active transport of sucrose becomes more negative

B active transport of sucrose becomes less negative
C diffusion of sucrose becomes more negative
D diffusion of sucrose becomes less negative

© UCLES 2007 9700/01/O/N/07 [Turn over

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25 The diagram represents a transverse section through a part of the root of a plant.

cortex
xylem
soil water

Which values of water potential (kPa) in the xylem and soil water help to explain why water
passes from the soil into the xylem across the cortex?

xylem soil water

A –700 kPa 0 kPa

B –1800 kPa –700 kPa
C 0 kPa –1800 kPa
D –700 kPa –1800 kPa

26 Translocation in plants moves sucrose from sources to sinks.

Which of the following can be a source and which a sink?

source sink

A germinating seeds green leaves

B green leaves storage roots
C phloem germinating seeds
D storage roots phloem

27 The red blood cell count of humans increases when they remain at high altitudes.

What is the effect of this?

A It increases the Bohr effect.

B It increases the rate of oxygen transport.
C It reduces the amount of haemoglobin per cell.
D It reduces the heart rate.

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28 A molecule of haemoglobin contains four haem groups. The haem groups contain iron atoms
which can bond reversibly with oxygen.

How many oxygen atoms can be carried by one haemoglobin molecule?

A 4 B 8 C 12 D 16

29 What is systolic blood pressure?

A the blood pressure in the arteries when the heart is relaxing

B the blood pressure in the left ventricle at the end of a contraction
C the maximum blood pressure in the arteries
D the maximum blood pressure in the right ventricle

30 Which cells or tissues are incorrectly paired with their function?

cells / tissues function

A cartilage reinforces the trachea

B ciliated epithelial cells move mucus over the surface of the trachea
C goblet cells produce enzymes to destroy bacteria
D smooth muscle constriction of the bronchioles

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31 The graph shows the volume of air breathed out quickly and with force, following a deep breath
in, for three different people, X, Y and Z.

5 X

4 Y

3
volume / dm3
2
Z
1

0
0 1 2 3 4 5
time / s

What is an explanation for the differences shown?

chronic bronchitis emphysema healthy lung function

A X Y Z
B X Z Y
C Y Z X
D Z Y X

32 Which statement is an example of epidemiological evidence linking smoking to lung cancer?

A Chemical analysis of tar from cigarettes shows that it contains carcinogens.

B Dogs made to inhale the smoke from cigarettes develop lung tumours.
C The incidence of lung cancer increases in a population as more cigarettes are smoked.
D When tar from cigarettes is rubbed onto the skin of mice, the mice develop skin tumours.

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33 Some facts about diseases are listed.

1 may be inherited from a parent

2 may be carried by a vector
3 may be caused by stress
4 may be passed on by contact
5 may enter through the mouth with food

Which numbered statements apply to infectious diseases?

A 1, 2 and 3
B 1, 3 and 5
C 2, 3 and 4
D 2, 4 and 5

34 Which disease is not likely to be passed directly from parent to child?

A cholera
B HIV / AIDS
C malaria
D tuberculosis

35 Which diseases can be cured by the use of antibiotics?

A cholera and tuberculosis

B HIV / AIDS and smallpox
C HIV / AIDS and tuberculosis
D smallpox and cholera

36 Which sequence of events correctly describes the action of a phagocyte when a pathogen is
encountered?

A endocytosis → digestion by lysosome enzymes → phagocytic vacuole formation →

exocytosis

B endocytosis → phagocytic vacuole formation → digestion by lysosome enzymes →

exocytosis

C exocytosis → phagocytic vacuole formation → digestion by lysosome enzymes →

phagocytosis

D phagocytosis → digestion by lysosome enzymes → phagocytic vacuole formation →

endocytosis

© UCLES 2007 9700/01/O/N/07 [Turn over

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37 Where are antibodies and antigens found?

on surface of on surface of
in blood plasma
pathogen macrophage

A antibody antibody antigen

B antibody antigen antibody
C antigen antibody antigen
D antigen antigen antibody

38 Which statement explains why two species cannot permanently occupy the same ecological
niche?
A The two species could not interbreed.
B The two species may be part of separate food webs.
C The two species would compete for the same resources.
D The two species would have different nutritional requirements.

39 Following an environmental disaster of a major volcanic eruption, the atmosphere contains

greatly increased amounts of dust.

How does this affect the following organisms?

nitrifying bacteria primary consumer producer secondary consumer

A decrease increase increase increase

B increase decrease decrease decrease
C increase no change no change decrease
D no change increase decrease no change

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40 The diagram shows the flow of energy through an ecosystem. Photosynthesis is the gross
productivity. Producers lose some energy in respiration and the energy left is the net
productivity.

This can also be expressed as an equation:

Net Productivity (NP) = Gross Productivity (GP) – Respiration (R)

Some of the net productivity passes to herbivores.

energy from
sunlight

photosynthesis

96 %
producers
gross productivity 4%

2.25 % lost in respiration

net productivity 1.75 %

1 % to
decomposers
0.75 %
primary
consumers

0.275 % to 0.4 % lost in respiration

decomposers
0.075 %
secondary
consumers

0.0685 % to 0.06 % lost in respiration

decomposers

Which calculation gives the proportion of net productivity passing to herbivores?

A
0.075
B
0.75
C
0.75
D
( 0.75 + 0.075 )
1.75 4 1.75 1.75

© UCLES 2007 9700/01/O/N/07

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