Leica M525 OH4

The Premium Surgical Microscope Solution for Precision Neurosurgery

Living up to Life

Leic
Leica Design by Christophe Apothloz

ca M525 OH4
Leica Microsystems stands for excellence in optics. Outstanding contrast, brilliance, sharpness,
resolution, color fidelity, and precision are hallmarks of Leica surgical microscopes. The Leica OH4
stand not only complements the LeicaM525 optics, but also improves the overall microsurgical experience with superior movement, innovative illumination, and user-friendly features.
Designed and manufactured using superior materials and the highest quality standards, the premium
Leica M525 OH4 is built for long service life and outstanding reliability. The Leica M525 OH4 fulfils
Leicas vision of providing the best viewing conditions and the greatest maneuverability to enable
successful surgery.

Optical Excellence
By integrating new glass, coatings, and design parameters,
Leicas OptiChrome technology delivers the extra working
distance, depth of focus, and light intensity needed for precision
microsurgery. It forms the basis for the worlds most advanced
optical system. Leica M525 optics deliver the following out
standing benefits:
Longer
Deeper
Brighter
Sharper
Smarter

32% extended working distance to 470 mm

30% increased depth of focus at same magnification
30% more light intensity
Higher contrast and crisper, sharper images
AutoIris magnification-controlled illumination

Advanced Illumination
Illumination Settings
Max

BrightCare
Adjusted

Working Distance

Max

Long
working distance

Decreased
working distance
creates burn
potential

BrightCare
auto adjustment for
safer illumination
levels (up to 60%
decrease based
on the working
distance)

Illumination Settings
LOW
Magnification

HIGH
Magnification

AutoIris
Adjusted

At low magnification, the field of

illumination (yellow)
fills the field of view
(green).

Previously, as
magnification
increased, the field
of view became
smaller, but the
illumination field
remained the same.
The illumination
outside the field
of view could
potentially cause
tissue burns (red).

Now, AutoIrisTM
automatically works
with the zoom,
decreasing the field
of illumination as
the field of view
decreases. There is
no peripheral
illumination to
cause tissue burns
outside the field of
view.

Illumination in an instant, always

The LeicaM525OH4 features two completely independent 300W
xenon arc-lamp illumination systems. The second system auto
matically activates in the event of lamp failure in the primary
system, which gives the surgeon confidence to know that surgery
will not be jeopardized due to lamp failure.
BrightCare Working-distance-controlled illumination
As a microscopes working distance decreases, the intensity
of the microscope light (without adjustments) increases. This
can pose a risk of tissue burns to patients. Leica Microsystems
BrightCare working-distance-controlled light intensity feature
addresses this issue to provide more safety for the patient by
adjusting light intensity based on the working distance.

AutoIris Magnification-controlled illumination

As magnification increases, the field of view becomes smaller,
but the illumination field remains the same. This can potentially
cause tissue burns. To provide additional safety for the patient,
Leica Microsystems AutoIris magnification-controlled illumination diameter auto-matically works with the zoom, providing a field
of illumination that is only as wide as the surgeons field of view.

Compact, yet provides superior reach and ample overhead room

The Leica M525 OH4 provides the highest overhead clearance
and the longest reach of any surgical microscope on the market
today. Because of the superior reach, the surgeon has the
ultimate flexibility to place the microscope wherever it is most
beneficial for the surgery.

COMPACT

DESIGN

S U P E R I O R O V E R H E A D

R E A C H

Superior Reach and Height

The Leica M525 OH4 allows perfect positioning for surgery
and takes up very little space in the operating room. The
Leica M525OH4 provides superior reach, height, and clearance,
which allows it to be conveniently located behind the surgeon
in the unique overhead position, or positioned anywhere around
or across the operating table.

LONG

REACH

Extraordinary movement
The LeicaM525OH4 offers a greatly expanded range of movement
in all dimensions for improved maneuverability. It takes half the
force to move the Leica OH4 than other high-end microscopes.
The system is vibration-free at all magnification levels. The stands
patented advanced movement system achieves perfect balance
in six axes and at all locations and angles of the microscope.
100 range of lateral movement provides the most difficult-tomaneuver side views.
150 inclination angle range combined with the most compact
microscope provides unmatched comfort, even in difficult positions.
Movement precision The LeicaM525OH4 has robotic functions
on two axes (X/Y) to allow a higher degree of precision movement.
With its 100 range of lateral movement the surgeon can easily achieve
the most challenging side views.

The 150 range of inclination angle

combined with a compact microscope
provides unmatched ergonomics even
in the most difficult positions.

The ergonomically designed mouth

switch allows the surgeon to easily
position the microscope, hands-free.

The ultra precise pistol grip provides

control of the microscope, stand, and
IGS and fluorescence functions.

Range of Movement

Fast and Precise Balance

True auto-balance
Leica Microsystems single button auto-balance-feature saves
valuable time. The surgeon activates this feature by simply push
ing the auto-balance button, which fully balances all six axes for
precise positioning.
Intraoperative re-balance
A microscope frequently needs re-balancing during surgery due
to the surgeons and assistants need to change positioning. It is
easy to re-balance the microscope intraoperatively, even through
a sterile drape. Simply push the AC/BC button, conveniently located
above the optical head, to quickly and accurately re-balance the
microscope in seconds.

Leica Microsystems graphical user

interface allows users to conveniently
and intuitively control all microscope
functions during surgery. Additionally,
there are hard keys for illumination
control and auto-balancing for added
safety.

10

Taking control
Fast, precise control over all of the stands functions, the micro
scope, and the accessories is vital in the operating room. The
LeicaM525OH4 features a touch screen with intuitive graphical
user interface.

Intraoperative re-balancing
for uninterrupted surgery.

Motorized Inclination and Tilt

The Leica M525 OH4 has robotic functions on two axes (X/Y) to
further enhance movement precision. The robotic functions can
be activated by hand and/or foot controls.
Combined with an IGS computer, the stands robotic ability allows
the microscope to follow the surgeons hand instruments, thus
eliminating the need for the surgeon to take his/her hand away
from the surgical site to move the microscope.

The handles ultra precise joystick

allows micrometric movements for tilt
and inclination. When preselected,
it can also, for example, control the
image injection functions.

Combined with an IGS computer, the

LeicaOH4 stands robotic ability allows
the microscope to follow the surgical
instruments.

11

Video screen integrated with floor stand

The Leica M525 OH4 features a built-in, movable video screen
arm, with three rotation axes and an inclination axis to best
position the large video flat screen (optional) into the perfect
position for all viewers. Also, all functions of the integrated video
recording system are conveniently and directly controlled via the
large video screen (using a keyboard, touch pad or touch screen
option).

Full image coverage on a 24

HD flat screen and wireless
video transfer to the surgeons
Apple device (optional).

Wireless transfer of high-quality HD videos and still images of

surgical cases to the AppleiPhone, iPodTouch or iPad
MedXMobile, available at the AppleApp Store, allows a surgeon
to wirelessly transfer surgical videos and stills directly from
the Med X Change HDMD recording unit to the surgeons
Apple iPhone, iPodTouch or iPad immediately upon procedure
completion. This new technology offers surgeons and staff yet
another method to transport, view, and share stunning, highquality content.

12

Integrated Digital Video

Ready for future imaging technologies
The selection of video options continually changes as imaging
technology evolves. The LeicaM525OH4 is an open architecture
system that allows the surgeon to upgrade components as
new video innovations become available. The Leica MDRS4
or the Med X Change HDMD high-definition digital recording
systems are integrated with the LeicaM525OH4 floor stand for
convenience and easy accessibility.

LeicaMDRS4 medical digital recording

system or HDMD high-definition
video system

Wide choice of Leica Video Adapters

All Leica video adapters offer an intra operative fine focus to
adjust the video focus. This enables the surgeon to always
achieve crisp and clear focus quality in documentation. For a
smooth surgical workflow, the surgeon can also choose between
manual or remote control. The remote control can be used sterile
(with a sterile cover) or unsterile by any person in the OR. Finally,
the c-mount interface allows the connection of a 1/2", 1/3", and
HD camera.

The Leica Zoom Video Adapter (top

left) allows focus and magnification
adjustments independently of the
surgeons view.
The Leica Dual Video Adapter (top
right) for vascular fluorescence cases
is NIR optimized with fine focus and
remote control.
The Manual and Remote Video
Adapters (bottom left and right) both
have a fine focus. Also, the remote
control allows the Remote Video
Adapter to be operated from any
position and in any situation in the OR.

13

OpenArchitecture
OpenArchitecture for IGS integration
The Leica DI C500 allows the surgeon to input data from any
external source such as MRI, CT, IGS, and endoscopes. With an
IGS computer the CT or MRI can be fully correlated to the image
in either eyepiece. The fully correlated image can be laid over the
actual image or a shutter can be used, which displays the actual
image in one eyepiece and the fully correlated image in the other
eyepiece.
In combination with the tool tracking capabilities
of an IGS system the optical axis and focal plane
of the microscope follows the tip of a navigated
tool in any lateral direction.

The LeicaDIC500
Dual Imaging Module
handles more data
formats than ever
before.

Neuro-endoscopy images
Non-correlated images, such as endoscope images, can be projected with the highest resolution and contrast available. With
the LeicaDIC500, the surgeon can view the endoscopy image in
whichever microscope eyepiece he or she chooses.

Tool tracking
In combination with the tool tracking capabilities of an IGS system,
the Leica M525 OH4 microscope can track an instrument in the
X,Y, and focus axis. Move the instrument and the microscope
follows without the surgeon touching the handle grips.

14

Integrated Fluorescence
Neurovascular fluorescence
The study of fluorescence microscopy has a long tradition at Leica
Microsystems, dating back to the beginning of the 20th century.
An indispensable component of biological research, fluorescence
science is now integrated with the technology of the surgical microscope to provide state-of-the-art neuro-vascular fluorescence.

Leica FL400*
The Leica FL400 enables
fluorescence-guided tumor
resection.

Malignant glioma, white light mode

Malignant glioma, blue light mode

ICG injection after 5 seconds:

Capillary view

ICG injection after 9 seconds:

Venous view

Leica FL800*

ICG injection after 2 seconds:

Arterial view

The Leica FL800 allows

surgeons to determine the
patency of blood flow through
vessels during surgery.
*Please check the status of Leica FL400 and Leica FL800 regulatory approval
with your local Leica Microsystems representative.

15

Superior
Reliability and Safety
Trusted reliability
Leica Microsystems utilizes superior materials and design technologies, and manufactures to the highest quality standards for
long service life and outstanding reliability. The LeicaM525OH4s
full metal construction is designed to withstand intensive use in
the operating room, remain precise throughout its life, and maintain
its value. Smart engineering and special vibration-dissipating
materials further support the stable, extra long swing arm. The
LeicaOH series has proven to be consistently reliable.

Typical structure of
a metal powder (Ag)
produced via inert
gas condensation
(nano powder).
Full metal construction

AgProtect: anti-microbial coating for added safety

Leica Microsystems antimicrobial nano silver coating, AgProtect,
provides outstanding protection to microscope users by reducing
exposure to surface pathogens. AgProtect covers the microscopes outside surface and protects the operator and other
individuals in the work area by penetrating the membranes of
microbes to prevent replication. Leica Microsystems develops
instruments with added safety for its customers, medical teams,
and their patients through AgProtect.

16

Technical Specifications

Dimensions in mm
17

ELECTRICAL DATA
Power connection

ACCESSORIES
1600 VA 50/60 Hz

LeicaULT500

180 stereo observer ports with selectable lateral or opposite

assistant: Main surgeon and opposite assistant 40% each eyepiece,
lateral assistant / video 20% each eyepiece / beam path

Second observer

Dual stereo attachment: 50% each eyepiece

Beam splitter

50% / 50%, 70% / 30%

Binocular tube

Variable angle 0 180

100 V (+10%/-15%), 120 V (+10%/-15%),

220 V (+10%/-15%), 240 V (+10%/-15%)
Safety class

Class1

LEICA M525 MICROSCOPE

Magnification

6:1 zoom, motorized

Focus

Motorized via multifocal lens, with manual adjustment

Eyepieces

Widefield eyepieces for eyeglass wearers 10 and 12.5,

dioptric setting 5 with adjustable eye cup

Objective

Multifocal lens, 207mm to 470mm variable working distance through

motorized lens, continuously adjustable, with manual override

Variable angle 30 150

Video adapter

Leica Remote Video Adapter (RVA),

55mm, 70 mm, 107 mm focal length, c-mount, with fine focus
Leica Zoom Video Adapter (ZVA), 3:1 zoom,
35mm to 100mm focal length, c-mount, with fine focus

Optional WD extender lens (not for IGS applications)

Illumination

Continuously adjustable illumination field diameter with Gaussshaped light distribution; continuously adjustable brightness at a
constant color temperature

Leica Manual Video Adapter (MVA),

55 mm, 70 mm, 107 mm focal length, c-mount, with fine focus

Leica NIR Dual Video Adapter (DVA),

60.6 mm, 79.5 mm focal length, c-mount, with fine focus
Imaging

LeicaDIC500 high resolution true dual imaging color module for

correlated and non correlated data display,
1024768pixel resolution, 256 grey scale

Main light source

High-performancee 300 Watt xenon arc-lamp through fiber optic

Emergency lamp

300 Watt xenon arc-lamp on a separate electrical system

Asepsis

AutoIris

Built-in, automatic, zoom-synchronized illumination field diameter,

with manual override and reset feature

Sterilizable protective glass for the objective; sterilizable

components for all drive knobs, commercially available drapes

Laser

BrightCare

Safety technology for the working distance-synchronized light

control

Various commercially available lasers and laser shutters can be

attached

IGS
OPTICAL DATA
Magnification range

1.2 12.8 with 10 eyepiece

Field of view

16.5mm to 180mm with 10 eyepiece

IGS interface /
compatibility

Open architecture for IGS systems

FLUORESCENCE
MICROSCOPE CARRIER
Rotation of optics

540

Lateral tilt

50 to left / 50 to right

Inclination tilt

30 / +120

XY speed

Zoom-correlated XY speed

Balancing

A, B, C, and D axes are fully automatic, each can be manually

balanced

Intraoperative
balancing

AC/BC button for automatic intraoperative re-balancing of the A and

C axes, and for re-balancing the B and C axes

Brakes

1 brake for A/B axis, 1 brake for C axis

Indicator

LED for fluorescence mode status, LED for video record status

18

Vascular
fluorescence

Optional Leica FL800 is available in the USA, EU, and most other
countries

Oncological
fluorescence

Optional Leica FL400 is available in the EU, and some other countries

Please check the status of regulatory approval with your local Leica Microsystems
representative.

Technical Specifications
Leica M525 OH4
LEICA OH4 FLOOR STAND

HD IMAGING

Type

Floor stand with six electromagnetic brakes

For more information, please refer to your local Leica Microsystems Sales Representative.

Base

720 mm 720 mm with four 360 rotatable casters of 130 mm

diameter each; one central, single step foot brake

Balancing

One button / two pushes for complete, automatic balancing of stand

and optics

In use

+10C to +40C (+50F to +104F), 30% to 95% rel. humidity,

500mbar to 1060mbar atmospheric pressure

Intraoperative
re-balancing

AC / BC button for automatic intraoperative re-balancing of the

AC axis and the BC axis

Storage

40C to +70C (40F to +158F), 10% to 100% rel. humidity,

500mbar to 1060mbar atmospheric pressure

Swing arm

Patented advanced movement system for perfect balance in six

axes, vibration-dissipating technology

Floor stand
control unit

New generation touch panel technology. The latest electronics

control for continuous control of all motor functions and the light
intensity. Data shown by means of LCD. Built-in BrightCare
technology for working distance synchronized light control.
ISUS Intelligent Setup System, menu selection based on unique
software for user-specific configuration, with built-in electronic
auto-diagnosis and user support. Software-independent hard keys
for illumination and auto-balancing. Indicator for main / backup
illumination and fluorescence modes. Open architecture for future
software developments.

Light source

Dual xenon arc-lamp illumination system and built-in, quick lamp

changer

Controls

10-function pistol grips for zoom, focus, all-free release of six

brakes, side button for user-defined brakes, motorized lateral tilt and
inclination (XY), Leica DI C500 or fluorescence functions. Except for
the all-free button, all functions are freely programmable.

AMBIENT CONDITIONS

LIMITATIONS OF USE
The LeicaM525OH4 surgical microscope may be used only in closed rooms and must be
placed on a solid floor.
Conformity
Council Directive 93/42/EEC on Medical Devices (MDD) and its amendments.
Classification: Class I, in compliance with Annex IX, rule 1 and rule 12 of the directive.
Medical Electrical Equipment, Part 1: General Requirements for Safety IEC 60601-1;
EN 60601-1; UL60601-1; CAN/CSA-C22.2 NO. 601.1-M90. Electromagnetic compatibility
IEC 60601-1-2; EN 60601-1-2. The Medical Division, within Leica Microsystems (Schweiz) AG,
holds the management system certificates for the international standards ISO 9001,
ISO 13485, and ISO 14001 relating to quality management, quality assurance and
environmental management.

Mouth switch for releasing the user defined brakes

12-function foot control, hand switch
Integration of
documentation

Prepared for integration of video- and digital recording systems.

Open architecture

Connectors

Numerous built-in connectors for video, IGS, and control data

transfer
Internal power 12 VDC, 19 VDC, and AC connections

Carrier for monitor

700 mm long
Flexible arm with 4 axes for the rotation and inclination required to
carry optional video monitor

Materials

All solid metal construction

Surface coating

Coated with antimicrobial paint (AgProtect)

Minimal height

In parked position 1945 mm

Range cantilever

Max. 1925 mm

Load

Min. 6.7 kg and max. 12.2 kg of accessories to the microscope

Weight

Approx. 320 kg without load

19

Leica Microsystems operates globally in four divisions,

where we rank with the market leaders.

Life Science Division

The Leica Microsystems Life Science Division supports the
imaging needs of the scientific community with advanced
innovation and technical expertise for the visualization,
measurement, and analysis of microstructures. Our strong
focus on understanding scientific applications puts Leica
Microsystems customers at the leading edge of science.

Industry Division
The Leica Microsystems Industry Divisions focus is to
support customers pursuit of the highest quality end result.
Leica Microsystems provide the best and most innovative
imaging systems to see, measure, and analyze the microstructures in routine and research industrial applications,
materials science, quality control, forensic science investigation, and educational applications.

Biosystems Division
The Leica Microsystems Biosystems Division brings histopathology labs and researchers the highest-quality,
most comprehensive product range. From patient to pathologist, the range includes the ideal product for each
histology step and high-productivity workflow solutions
for the entire lab. With complete histology systems featuring innovative automation and Novocastra reagents,
Leica Microsystems creates better patient care through
rapid turnaround, diagnostic confidence, and close customer collaboration.

Medical Division
The Leica Microsystems Medical Divisions focus is to
partner with and support surgeons and their care of patients with the highest-quality, most innovative surgical
microscope technology today and into the future.

The statement by Ernst Leitz in 1907, with the user, for the user, describes the fruitful collaboration
with end users and driving force of innovation at Leica Microsystems. We have developed five
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Science, and Continuous Improvement. For us, living up to these values means: Living up to Life.

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10 M1 110 0en/- Leica Microsystems (Schweiz) AG CH-9435 Heerbrugg, 2011 Printed in Switzerland VI.2011 RDV Illustrations, descriptions and technical data are not binding and may be changed without notice.
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