Expanded Program for Immunization (EPI)
Principles of EPI
1. Epidemiological situation
2. Mass approach
3. Basic Health Service
The 7 immunizable diseases
1. Tuberculosis
2. Diptheria
3. Pertussis
4. Measles
5. Poliomyelitis
6. Tetanus
7. Hepatitis B
Target Setting
Infants 0-12 months
Pregnant and Post Partum Women
School Entrants/ Grade 1 / 7 years old
Objectives of EPI
To reduce morbidity and mortality rates among infants and children from six childhood immunizable disease
Elements of EPI
Target Setting
Cold chain Logistic Management- Vaccine distribution through cold chain is designed to ensure that the vaccines
were maintained under proper environmental condition until the time of administration.
Information, Education and Communication (IEC)
Assessment and evaluation of Over-all performance of the program
Surveillance and research studies
Administration of vaccines
Vaccine
Content
Form & Dosage
BCG (Bacillus Calmette Live attenuated
Guerin)
bacteria
Freeze dried
Infant- 0.05ml
# of
Doses
Route
ID
liquid-0.5ml
IM
Preschool-0.1ml
DPT (Diphtheria
Pertussis Tetanus)
DT- weakened toxin
P-killed bacteria
OPV (Oral Polio
Vaccine)
weakened virus
liquid-2drops
Oral
Hepatitis B
Plasma derivative
Liquid-0.5ml
IM
Measles
Weakened virus
Freeze dried- 0.5ml
Subcutaneous
Schedule of Vaccines
Vaccine Age at 1st dose
Interval
between dose
Protection
BCG
At birth
BCG is given at the earliest
possible age protects against the
possibility of TB infection from
the other family members
DPT
6 weeks
4 weeks
An early start with DPT reduces
the chance of severe pertussis
OPV
6weeks
4weeks
The extent of protection against
polio is increased the earlier
OPV is given.
Hepa B @ birth
@birth,6th
An early start of Hepatitis B
week,14th week reduces
the chance of being infected and
becoming a carrier.
Measles 9m0s.-11m0s.
At least 85% of measles can be
prevented by immunization at
this age.
6 months earliest dose of measles given in case of outbreak
9months-11months- regular schedule of measles vaccine
15 months- latest dose of measles given
4-5 years old- catch up dose
Fully Immunized Child (FIC)- less than 12 months old child with complete immunizations of DPT, OPV, BCG,
Anti Hepatitis, Anti measles.
Tetanus Toxiod Immunization
Schedule for Women
Vaccine
Minimum age
%
interval
protected
Duration of
Protection
TT1
As early as
possible
0%
TT2
4 weeks later
80%
3 years
TT3
6 months later
95%
5 years
TT4
1year later/during 99%
next pregnancy
10 years
TT5
1 year later/third
pregnancy
Lifetime
99%
There is no contraindication to immunization except when the child is immunosuppressed or is very, very ill (but
not slight fever or cold). Or if the child experienced convulsions after a DPT or measles vaccine, report such to the
doctor immediately.
Malnutrition is not a contraindication for immunizing children rather; it is an indication for immunization since
common childhood diseases are often severe to malnourished children.
Cold Chain under EPI
Cold Chain is a system used to maintain potency of a vaccine from that of manufacture to the time it is given to
child or pregnant woman.
The allowable timeframes for the storage of vaccines at different levels are:
o 6months- Regional Level
o 3months- Provincial Level/District Level
o 1month-main health centers-with ref.
o Not more than 5days- Health centers using transport boxes.
Most sensitive to heat: Freezer (-15 to -25 degrees C)
o OPV
o Measles
Sensitive to heat and freezing (body of ref. +2 to +8 degrees Celsius)
o BCG
o DPT
o Hepa B
o TT
Use those that will expire first, mark X/ exposure, 3rd- discard,
Transport-use cold bags let it stand in room temperature for a while before storing DPT.
Half life packs: 4hours-BCG, DPT, Polio, 8 hours-measles, TT, Hepa B.
FEFO (first expiry and first out) - vaccine is practiced to assure that all vaccines are utilized before the expiry
date. Proper arrangement of vaccines and/or labeling of vaccines expiry date are done to identify those near to
expire vaccines.