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Gastric Adenocarcinoma

The document outlines the stages of stomach cancer development from initial risk factors through metastasis and symptoms. It begins with non-modifiable and modifiable risk factors such as age, sex, chronic gastritis, gastric polyps, diet, and smoking. It then describes the process of DNA damage and cell mutation leading to cancer cell growth, angiogenesis to supply blood to cancer cells, metastasis to nearby organs, and ultimately symptoms like pain, bleeding, fatigue, and nutritional imbalances.

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Jimel Vital Carreon
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677 views4 pages

Gastric Adenocarcinoma

The document outlines the stages of stomach cancer development from initial risk factors through metastasis and symptoms. It begins with non-modifiable and modifiable risk factors such as age, sex, chronic gastritis, gastric polyps, diet, and smoking. It then describes the process of DNA damage and cell mutation leading to cancer cell growth, angiogenesis to supply blood to cancer cells, metastasis to nearby organs, and ultimately symptoms like pain, bleeding, fatigue, and nutritional imbalances.

Uploaded by

Jimel Vital Carreon
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Non-modifiable risk factors: Age(40 y/o and above) Sex (male)

Modifiable risk factors: Chronic gastritis Gastric polyps Diet (smoked foods) Smoking

Damage to DNA Weakened immune system

Exposure to carcinogens

Mutation of cells into cancer cells

Exposure of mutated cells to promoters

Activation of cancer cells

Mutation of protooncogenes and tumor suppressor genes

Growth of cancer cells

Further growth of cancer cells

Formation of oncogenes and diasability of tumor suppressor genes Production of cancer cells

Formation of cancer cell colony

Metastasis to different parts of the body

Cancer cells will join the blood stream

Formation of new blood vessels towards cancer cells (angiogenesis)

Blood supply

The body will supply more blood to the cancer cells

Anemia

Further nourishment to the cancer cells

Further growth of cancer cells

Disruption of cell membrane

Metastasis to nearby organs

Stress to the stomach Gastric function

Formation of ulcer to gastric mucosa

Exposure of nerve endings

Pain

Bleeding will occur Indigestion Blood will go to the stool Lymphatic system will drain excess fluids Cancer cells will join Metastasis to different parts of the body (+) FOBT

Blood supply

Anemia

Oxygen and nutrients supply to the body

Fatigue

Appetite

Imbalanced nutrition

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