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Review
. 2018 Jul;28(7):2845-2855.
doi: 10.1007/s00330-017-5246-5. Epub 2018 Feb 9.

Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines

Aart J van der Molen  1 , Peter Reimer  2 , Ilona A Dekkers  1 , Georg Bongartz  3 , Marie-France Bellin  4 , Michele Bertolotto  5 , Olivier Clement  6 , Gertraud Heinz-Peer  7 , Fulvio Stacul  8 , Judith A W Webb  9 , Henrik S Thomsen  10
Affiliations
Review

Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines

Aart J van der Molen et al. Eur Radiol. 2018 Jul.

Abstract

Purpose: The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers. AREAS COVERED IN PART 1: Topics reviewed include the terminology used, the best way to measure eGFR, the definition of PC-AKI, and the risk factors for PC-AKI, including whether the risk with intravenous and intra-arterial contrast medium differs.

Key points: • PC-AKI is the preferred term for renal function deterioration after contrast medium. • PC-AKI has many possible causes. • The risk of AKI caused by intravascular contrast medium has been overstated. • Important patient risk factors for PC-AKI are CKD and dehydration.

Keywords: Acute kidney injury; Contrast media; Glomerular filtration rate; Practice guidelines as topic; Risk factors.

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Conflict of interest statement

Guarantor

The scientific guarantor of this publication is Prof. Henrik S. Thomsen.

Conflict of interest

Aart van der Molen has received incidental payments for lectures and chairmanships at scientific meetings for contrast agent safety related issues (contrast agent reactions, Gd-retention) from GE, Bayer, Bracco and Guerbet

Fulvio Stacul has received lecture fees from Bracco and Guerbet

Olivier Clément has received lecture fees from Bracco and Guerbet

The other authors of this manuscript declare no relationships with any companies whose products and services may be related to the subject matter of this article.

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